AGÕęČ˹ٷ½

STOCK TITAN

Creative Medical Technology Holdings Receives Notice of Allowance for ImmCelz� for Treatment of Heart Failure and/or Post Infarct Pathological Remodeling

Rhea-AI Impact
(Moderate)
Rhea-AI Sentiment
(Positive)
Tags

Creative Medical Technology (NASDAQ: CELZ) has received a Notice of Allowance from the USPTO for a patent application covering their ImmCelz� treatment for heart failure and post-infarct pathological remodeling. The patent, effective until at least 2040, will protect the company's proprietary treatment delivered through an ultra-minimally invasive outpatient procedure.

The potential market is significant, with over 5 million heart failure patients in the United States and an additional 6 million patients with chronic chest pain who could benefit from the treatment. The patent strengthens Creative Medical's intellectual property portfolio in regenerative medicine and cell-based therapies.

Creative Medical Technology (NASDAQ: CELZ) ha ricevuto un Avviso di Concessione dall'USPTO per una domanda di brevetto riguardante il loro trattamento ImmCelz� per l'insufficienza cardiaca e il rimodellamento patologico post-infartuale. Il brevetto, valido almeno fino al 2040, proteggerà il trattamento proprietario dell'azienda somministrato tramite una procedura ambulatoriale ultra-minimamente invasiva.

Il mercato potenziale ĆØ significativo, con oltre 5 milioni di pazienti con insufficienza cardiaca negli Stati Uniti e altri 6 milioni di pazienti con dolore toracico cronico che potrebbero beneficiare del trattamento. Il brevetto rafforza il portafoglio di proprietĆ  intellettuale di Creative Medical nella medicina rigenerativa e nelle terapie a base cellulare.

Creative Medical Technology (NASDAQ: CELZ) ha recibido un Aviso de Concesión por parte de la USPTO para una solicitud de patente que cubre su tratamiento ImmCelzā„� para insuficiencia cardĆ­aca y remodelación patológica post-infarto. La patente, vigente al menos hasta 2040, protegerĆ” el tratamiento exclusivo de la compaƱƭa administrado mediante un procedimiento ambulatorio ultra mĆ­nimamente invasivo.

El mercado potencial es significativo, con mÔs de 5 millones de pacientes con insuficiencia cardíaca en Estados Unidos y otros 6 millones de pacientes con dolor torÔcico crónico que podrían beneficiarse del tratamiento. La patente fortalece el portafolio de propiedad intelectual de Creative Medical en medicina regenerativa y terapias basadas en células.

Creative Medical Technology (NASDAQ: CELZ)ėŠ� 심부ģ � ė°� ģ‹¬ź·¼ź²½ģƒ‰ ķ›� 병적 ģž¬ķ˜•ģ„±ģ„ ģœ„ķ•œ ImmCelzā„� 치료ė²�ģ—� ėŒ€ķ•� ķŠ¹ķ—ˆ ģ¶œģ›ģ—� ėŒ€ķ•� USPTOė”œė¶€ķ„� ķ—ˆź°€ ķ†µģ§€ģ„œė„¼ ė°›ģ•˜ģŠµė‹ˆė‹�. ģ� ķŠ¹ķ—ˆėŠ� ģµœģ†Œ 2040ė…„ź¹Œģ§€ ģœ ķšØķ•˜ė©°, ķšŒģ‚¬ģ� ė…ģ  ģ¹˜ė£Œė²•ģ„ ģ“ˆģ†Œķ˜� ģµœģ†Œ 침습 ģ™øėž˜ ģ‹œģˆ ģ� 통핓 볓호ķ•� ź²ƒģž…ė‹ˆė‹¤.

미국 ė‚� 500ė§� ėŖ� ģ“ģƒģ� 심부ģ � ķ™˜ģžź³� ė§Œģ„± ķ‰ķ†µ ķ™˜ģž 600ė§� ėŖ�ģ� ģ� ģ¹˜ė£Œė²•ģ˜ ķ˜œķƒģ� ė°›ģ„ ģˆ� ģžˆģ–“ ģž ģž¬ ģ‹œģž„ģ� ķ½ė‹ˆė‹�. ģ� ķŠ¹ķ—ˆėŠ� ģž¬ģƒ ģ˜ķ•™ ė°� ģ„øķ¬ 기반 치료 ė¶„ģ•¼ģ—ģ„œ Creative Medicalģ� ģ§€ģ � ģž¬ģ‚° ķ¬ķŠøķ“ė¦¬ģ˜¤ė„¼ ź°•ķ™”ķ•©ė‹ˆė‹�.

Creative Medical Technology (NASDAQ : CELZ) a reƧu un Avis d'Acceptation de l'USPTO pour une demande de brevet couvrant leur traitement ImmCelzā„� pour l'insuffisance cardiaque et le remodelage pathologique post-infarctus. Le brevet, valable au moins jusqu'en 2040, protĆ©gera le traitement exclusif de l'entreprise administrĆ© par une procĆ©dure ambulatoire ultra-minimale invasive.

Le marchĆ© potentiel est important, avec plus de 5 millions de patients souffrant d'insuffisance cardiaque aux Ɖtats-Unis et 6 millions de patients supplĆ©mentaires souffrant de douleurs thoraciques chroniques qui pourraient bĆ©nĆ©ficier du traitement. Ce brevet renforce le portefeuille de propriĆ©tĆ© intellectuelle de Creative Medical dans la mĆ©decine rĆ©gĆ©nĆ©rative et les thĆ©rapies Ć  base de cellules.

Creative Medical Technology (NASDAQ: CELZ) hat von der USPTO eine Zulassungsmitteilung für eine Patentanmeldung erhalten, die ihre ImmCelzā„�-Behandlung für Herzinsuffizienz und postinfarktbedingtes pathologisches Remodeling abdeckt. Das Patent, das mindestens bis 2040 gültig ist, schützt die firmeneigene Behandlung, die durch ein ultra-minimalinvasives ambulantes Verfahren verabreicht wird.

Der potenzielle Markt ist erheblich, mit über 5 Millionen Herzinsuffizienzpatienten in den Vereinigten Staaten und weiteren 6 Millionen Patienten mit chronischen Brustschmerzen, die von der Behandlung profitieren könnten. Das Patent stärkt das geistige Eigentumsportfolio von Creative Medical im Bereich der regenerativen Medizin und zellbasierten Therapien.

Positive
  • Patent protection secured until at least 2040 for ImmCelz treatment
  • Large addressable market of over 11 million potential patients in the US
  • Treatment delivered through ultra-minimally invasive outpatient procedure
  • Strengthens company's intellectual property portfolio in regenerative medicine
Negative
  • Product still in clinical-stage, not yet FDA approved
  • No revenue generation from this treatment currently

PHOENIX, July 11, 2025 (GLOBE NEWSWIRE) -- Creative Medical Technology Holdings, Inc. (NASDAQ: CELZ) (ā€œCreative Medicalā€� or the ā€œCompanyā€�), a clinical-stage biotechnology company specializing in regenerative medicine, today announced that it has received a Notice of Allowance from the United States Patent and Trademark Office (USPTO) for a U.S. patent application titled, ā€�Treatment Of Heart Failure And/Or Post Infarct Pathological Remodeling By Ex Vivo Reprogrammed Immune Cells.ā€�

Once granted, the patent will be in effect until at least 2040.

The patent has broad claims to treat patients who are at risk of developing or who already have heart failure with the Company’s proprietary ImmCelz product.Ā  Some patients who experience a heart attack develop post-infarct pathological remodeling, which can lead to reduced heart function and potentially result in heart failure. The total treatable heart failure population in the United States is greater than five million patients. There are also over six million patients who have chronic chest pain (refractory angina) despite maximal medical and surgical therapy who may also benefit from the ImmCelz product. The ImmCelz product is delivered to the patient via an ultra-minimally invasive outpatient procedure.

"This Notice of Allowance further strengthens our already robust intellectual property portfolio and reflects the potential of our cell-based technology to develop therapies that support the reprogramming, regrowth, and repair of the body across multiple indications,ā€� said Timothy Warbington, CEO of Creative Medical. ā€œThis latest allowance adds further value to our franchise and will help to support the continuing growth and evolution of our regenerative medicine platform."

About ImmCelzTM
Creative Medical’s ImmCelz platform utilizes a patient’s own extracted immune cells that are then ā€œreprogrammed/superchargedā€� by culturing them outside the patient’s body with optimized cell-free factors. The immune cells are then re-injected into the patient from whom they were extracted. The Company believes that this process endows the immune cells with regenerative properties (or ā€œsuperchargesā€� them) on top of their original innate functions providing them with the ability to treat multiple indications.

About Creative Medical Technology Holdings
Creative Medical Technology Holdings, Inc. (NASDAQ: CELZ) is a clinical-stage biotechnology company pioneering regenerative medicine solutions for multiple indications, including pain management, neurology, and urology. The company leverages cutting-edge cell therapy technologies to develop transformative treatments aimed at improving patient outcomes.

For more information, visit .

Forward Looking Statements
This news release may contain forward-looking statements including, but not limited to, comments regarding the potential for the Company’s cell-based therapies and the strength of its intellectual property portfolio. Forward-looking statements address future events and conditions and, therefore, involve inherent risks and uncertainties. Actual results may differ materially from those currently anticipated in such statements. See the periodic and other reports filed by Creative Medical Technology Holdings, Inc. with the Securities and Exchange Commission and available on the Commission's website atĀ 

Contact:
Creative Medical Technology Holdings, Inc.
[email protected]

Investor Relations:
Devin Sullivan, Managing Director
The Equity Group Inc.

Conor Rodriguez
Associate


FAQ

What patent did Creative Medical Technology (CELZ) receive for ImmCelz treatment?

CELZ received a Notice of Allowance from the USPTO for a patent titled 'Treatment Of Heart Failure And/Or Post Infarct Pathological Remodeling By Ex Vivo Reprogrammed Immune Cells', effective until at least 2040.

How many potential patients could benefit from CELZ's ImmCelz treatment?

Over 11 million patients in the US could potentially benefit, including 5 million heart failure patients and 6 million patients with chronic chest pain (refractory angina).

How is the ImmCelz treatment administered to patients?

The ImmCelz product is administered through an ultra-minimally invasive outpatient procedure.

What medical conditions does the new CELZ patent cover for ImmCelz treatment?

The patent covers the treatment of heart failure and post-infarct pathological remodeling, including patients at risk of developing these conditions.

What is the current development stage of CELZ's ImmCelz treatment?

Creative Medical Technology is currently in the clinical-stage of development for the ImmCelz treatment.
Creative Med Technology Hldgs

NASDAQ:CELZ

CELZ Rankings

CELZ Latest News

CELZ Stock Data

6.89M
2.55M
2.02%
1.71%
10.58%
Biotechnology
Biological Products, (no Disgnostic Substances)
United States
PHOENIX