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OKYO Pharma Receives $1.9 Million in Non-Dilutive Funding to Accelerate Development of Urcosimod for Neuropathic Corneal Pain

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OKYO Pharma (NASDAQ: OKYO) has secured $1.9 million in non-dilutive funding to accelerate the development of urcosimod, its lead drug candidate for treating Neuropathic Corneal Pain (NCP). The funding will support ongoing R&D programs and advance clinical milestones without impacting existing shareholder equity.

NCP is a severely debilitating ocular condition characterized by chronic nerve-related pain that currently has no FDA-approved treatments. The company will use the funds to advance clinical development, expand R&D efforts, and progress urcosimod's regulatory pathway, demonstrating its commitment to fiscal responsibility while developing innovative therapies.

OKYO Pharma (NASDAQ: OKYO) ha ottenuto 1,9 milioni di dollari di finanziamenti non diluitivi per accelerare lo sviluppo di urcosimod, il suo farmaco principale per il trattamento del Dolore Corneale Neuropatico (NCP). Questi fondi sosterranno i programmi di ricerca e sviluppo in corso e permetteranno di raggiungere importanti traguardi clinici senza influire sull'equity degli azionisti attuali.

Il NCP è una condizione oculare gravemente debilitante, caratterizzata da un dolore cronico legato ai nervi, per la quale attualmente non esistono trattamenti approvati dalla FDA. L'azienda utilizzerà i fondi per far progredire lo sviluppo clinico, ampliare gli sforzi di ricerca e sviluppo e avanzare nel percorso regolatorio di urcosimod, dimostrando così il suo impegno nella responsabilità finanziaria mentre sviluppa terapie innovative.

OKYO Pharma (NASDAQ: OKYO) ha asegurado 1,9 millones de dólares en financiamiento no dilutivo para acelerar el desarrollo de urcosimod, su principal candidato a fármaco para tratar el Dolor Corneal Neuropático (NCP). Los fondos apoyarán los programas de I+D en curso y permitirán avanzar en hitos clínicos sin afectar el capital de los accionistas existentes.

El NCP es una condición ocular gravemente discapacitante, caracterizada por dolor crónico relacionado con los nervios, para la cual actualmente no existen tratamientos aprobados por la FDA. La compañía utilizará los fondos para avanzar en el desarrollo clínico, ampliar los esfuerzos de I+D y progresar en la vía regulatoria de urcosimod, demostrando su compromiso con la responsabilidad financiera mientras desarrolla terapias innovadoras.

OKYO Pharma (NASDAQ: OKYO)� 신경병성 각막통증(NCP) 치료� 위한 주력 약물 후보� 유코시모� 개발 가속화� 위해 희석되지 않는 190� 달러� 자금� 확보했습니다. � 자금은 현재 진행 중인 연구개발 프로그램� 지원하� 기존 주주 지분에 영향� 주지 않으면서 임상 단계� 진전� 도모� 것입니다.

NCP� 만성 신경 관� 통증� 특징� 심각� 안구 질환으로, 현재 FDA 승인 치료제가 전무� 상태입니�. 회사� � 자금� 임상 개발 촉진, 연구개발 확대, 유코시모드의 규제 절차 진행� 사용� 예정이며, 혁신적인 치료� 개발� 함께 재정 책임� 다하겠다� 의지� 보여줍니�.

OKYO Pharma (NASDAQ : OKYO) a obtenu 1,9 million de dollars de financement non dilutif afin d'accélérer le développement d'urcosimod, son principal candidat-médicament pour le traitement de la douleur cornéenne neuropathique (NCP). Ce financement soutiendra les programmes de R&D en cours et permettra de faire progresser les étapes cliniques sans affecter les actions des actionnaires actuels.

La NCP est une affection oculaire sévèrement invalidante, caractérisée par une douleur chronique liée aux nerfs, pour laquelle il n'existe actuellement aucun traitement approuvé par la FDA. L'entreprise utilisera ces fonds pour faire avancer le développement clinique, élargir les efforts de R&D et progresser dans la voie réglementaire d'urcosimod, démontrant ainsi son engagement envers la responsabilité financière tout en développant des thérapies innovantes.

OKYO Pharma (NASDAQ: OKYO) hat 1,9 Millionen US-Dollar an nicht verwässernden Finanzmitteln erhalten, um die Entwicklung von Urcosimod, ihrem führenden Arzneimittelkandidaten zur Behandlung von neuropathischem Hornhautschmerz (NCP), zu beschleunigen. Die Finanzierung wird laufende F&E-Programme unterstützen und klinische Meilensteine vorantreiben, ohne die bestehende Aktionärsbeteiligung zu verwässern.

NCP ist eine schwerwiegende, beeinträchtigende Augenerkrankung, die durch chronische nervenbedingte Schmerzen gekennzeichnet ist und derzeit keine von der FDA zugelassenen Behandlungen hat. Das Unternehmen wird die Mittel nutzen, um die klinische Entwicklung voranzutreiben, die F&E-Bemühungen auszuweiten und den regulatorischen Weg von Urcosimod zu fördern, wodurch es sein Engagement für finanzielle Verantwortung bei der Entwicklung innovativer Therapien unterstreicht.

Positive
  • Secured $1.9 million in non-dilutive funding preserving shareholder value
  • Targeting an unmet medical need with no FDA-approved treatments
  • Funding strengthens ability to advance clinical milestones and R&D efforts
Negative
  • Current development stage suggests revenue generation still far in the future
  • Funding amount relatively modest for clinical development needs

Insights

OKYO's $1.9M non-dilutive funding strengthens its financial position while advancing its lead candidate for an unmet medical need.

OKYO Pharma has secured $1.9 million in non-dilutive funding to accelerate the development of urcosimod, its lead drug candidate targeting Neuropathic Corneal Pain (NCP). This financing represents a meaningful development for a clinical-stage biotech company of OKYO's size. The non-dilutive nature of this capital is particularly significant as it allows the company to advance its clinical program without issuing additional shares that would dilute existing shareholders' ownership positions.

The funding strengthens OKYO's cash position at a critical juncture in urcosimod's development. NCP represents a substantial market opportunity as an underserved condition with no FDA-approved treatments. Patients suffering from this condition experience chronic and often severe nerve-related pain, creating a significant unmet medical need that urcosimod aims to address.

From a financial perspective, this capital infusion extends OKYO's operational runway and reduces near-term financing pressure. For clinical-stage biotechs without marketed products generating revenue, securing non-dilutive funding is exceptionally valuable. This $1.9 million will support specific R&D initiatives, including advancing clinical milestones and regulatory pathway development for urcosimod.

The company's focus on a condition lacking approved therapies positions it in a potentially advantageous regulatory environment, where treatments for unmet medical needs can sometimes benefit from accelerated review processes. This funding will help OKYO navigate the complex and costly clinical development landscape while maintaining its existing capital structure � a positive signal for current investors concerned about dilution.

LONDON and NEW YORK, July 17, 2025 (GLOBE NEWSWIRE) -- OKYO Pharma Limited (NASDAQ: ), an ophthalmology-focused bio-pharmaceutical company which is developing urcosimod to treat neuropathic corneal pain (NCP), an ocular condition associated with chronic and often severe nerve-related pain but without an FDA-approved therapy, today announced it has received $1.9 million in non-dilutive funding to support its ongoing research and development programs. The funding will specifically accelerate the clinical development of urcosimod, OKYO’s lead drug candidate for the treatment of Neuropathic Corneal Pain (NCP) � a severely debilitating ocular condition with no FDA-approved treatments.

This non-dilutive capital strengthens OKYO Pharma’s ability to execute on its development strategy without impacting existing shareholder equity. The funds will be used to advance key clinical milestones, expand R&D efforts, and build momentum behind urcosimod’s regulatory pathway.

“This non-dilutive funding is a significant milestone for OKYO Pharma and allows the company to drive innovation and accelerate solutions that could improve patient outcomes,� said Gary S. Jacob, PhD, CEO of OKYO Pharma. “Neuropathic Corneal Pain is a devastating and underdiagnosed condition with no approved therapies. These funds allow us to aggressively pursue our mission of bringing urcosimod to patients who desperately need relief, without diluting shareholder value. It’s an exciting step forward for our company and for the field of ocular pain treatment.�

The infusion of non-dilutive funding underscores OKYO Pharma’s commitment to maintaining fiscal responsibility while pursuing transformative therapies that address critical unmet medical needs.

About NCP
 is a condition that causes severe pain and sensitivity of the eyes, face, or head. The exact cause of neuropathic corneal pain is unknown but is thought to result from nerve damage to the  combined with . Neuropathic corneal pain, which can exhibit as a severe, chronic, debilitating condition in patients suffering from a host of ophthalmic conditions, is presently treated by various topical and systemic treatments in an off-label fashion. Notably, there is no FDA approved drug to treat this debilitating condition.

About Urcosimod (Formerly called OK-101)
Urcosimod is a lipid conjugated chemerin peptide agonist of the ChemR23 G-protein coupled receptor which is typically found on immune cells of the eye responsible for the inflammatory response, as well as on neurons and glial cells in the dorsal root ganglion. Urcosimod was developed using a membrane-anchored-peptide technology to produce a novel long-acting drug candidate for treating ocular diseases. Urcosimod has been shown to produce anti-inflammatory and pain-reducing activities in mouse models of dry eye disease and corneal neuropathic pain, respectively, and is designed to combat washout through the inclusion of the lipid anchor built into the drug molecule to potentially enhance the efficacy of urcosimod within the ocular environment. Urcosimod showed clear statistical significance in multiple endpoints in a 240-patient completed Phase 2, multi-center, double-masked, placebo-controlled trial to treat dry eye disease, and just completed a randomized, placebo-controlled, double-masked Phase 2 trial of urcosimod to treat neuropathic corneal pain.

About OKYO
OKYO Pharma Limited (NASDAQ: OKYO) is a clinical stage biopharmaceutical company developing innovative therapies for the treatment of neuropathic corneal pain and dry eye disease, with ordinary shares listed for trading on the NASDAQ Capital Market. OKYO is focused on the discovery and development of novel molecules to treat neuropathic corneal pain and dry eye disease. A Phase 2 trial of urcosimod to treat neuropathic corneal pain patients was just completed by OKYO.

For further information, please visit .

Inquiries:

OKYO Pharma LimitedGary S. Jacob, Chief Executive Officer917-497-7560
Business Development & Investor RelationsPaul Spencer+44 (0)20 7495 2379


FAQ

How much non-dilutive funding did OKYO Pharma (NASDAQ: OKYO) receive in July 2025?

OKYO Pharma received $1.9 million in non-dilutive funding to accelerate the development of urcosimod for Neuropathic Corneal Pain.

What is OKYO Pharma developing urcosimod for?

OKYO Pharma is developing urcosimod to treat Neuropathic Corneal Pain (NCP), a severely debilitating ocular condition with chronic nerve-related pain and no FDA-approved treatments.

How will OKYO use the $1.9 million funding?

The funding will be used to advance clinical milestones, expand R&D efforts, and build momentum behind urcosimod's regulatory pathway.

What is the current treatment landscape for Neuropathic Corneal Pain?

Currently, there are no FDA-approved treatments for Neuropathic Corneal Pain, making it an area of significant unmet medical need.

How does the funding impact OKYO Pharma shareholders?

The funding is non-dilutive, meaning it does not impact existing shareholder equity while strengthening the company's development capabilities.
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