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Viatris Announces Five Data Presentations on Novel Fast-Acting Meloxicam (MR-107A-02) at PAINWeek 2025 Conference

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Viatris (Nasdaq: VTRS) announced the presentation of five scientific abstracts at the upcoming PAINWeek 2025 conference, showcasing data from its Phase 3 program for a novel fast-acting meloxicam formulation (MR-107A-02) in treating moderate-to-severe acute surgical pain.

The presentations, scheduled for September 2-5, 2025, in Las Vegas, will feature results from two pivotal studies in herniorrhaphy and bunionectomy surgery models. The data includes pharmacokinetics, efficacy, safety, and opioid use reduction findings. Four abstracts will have live presentations on September 4, while one will be a poster-only presentation.

Viatris (Nasdaq: VTRS) ha annunciato la presentazione di cinque abstract scientifici al prossimo congresso PAINWeek 2025, mostrando dati dal suo programma di Fase 3 per una nuova formulazione di meloxicam ad azione rapida (MR-107A-02) nel trattamento del dolore chirurgico acuto da moderato a grave.

Le presentazioni, previste dal 2 al 5 settembre 2025 a Las Vegas, presenteranno i risultati di due studi fondamentali condotti su modelli chirurgici di ernioplastica e alluce valgo. I dati includono farmacocinetica, efficacia, sicurezza e riduzione dell'uso di oppioidi. Quattro abstract saranno presentati dal vivo il 4 settembre, mentre uno sarà disponibile solo in formato poster.

Viatris (Nasdaq: VTRS) anunció la presentación de cinco resúmenes científicos en la próxima conferencia PAINWeek 2025, mostrando datos de su programa de Fase 3 para una nueva formulación de meloxicam de acción rápida (MR-107A-02) en el tratamiento del dolor quirúrgico agudo moderado a severo.

Las presentaciones, programadas del 2 al 5 de septiembre de 2025 en Las Vegas, incluirán resultados de dos estudios clave en modelos quirúrgicos de herniorrafia y bunionectomía. Los datos abarcan farmacocinética, eficacia, seguridad y reducción en el uso de opioides. Cuatro resúmenes serán presentados en vivo el 4 de septiembre, mientras que uno será solo en formato póster.

Viatris (나스�: VTRS)� 다가오는 PAINWeek 2025 학회에서 5개의 과학 초록� 발표한다� 밝혔으며, 중등도에� 중증� 급성 수술 통증 치료� 위한 신속 작용 멜록시캄 제형(MR-107A-02)� 3� 프로그램 데이터를 선보� 예정입니�.

2025� 9� 2일부� 5일까지 라스베이거스에서 열리� 발표에서� 탈장 봉합술과 무지외반� 수술 모델� 대상으� � � 건의 주요 연구 결과가 포함됩니�. 데이터에� 약동�, 효능, 안전� � 오피오이� 사용 감소 결과가 포함됩니�. 4개의 초록은 9� 4� 라이� 발표� 진행되며, 1개는 포스� 발표로만 진행됩니�.

Viatris (Nasdaq : VTRS) a annoncé la présentation de cinq résumés scientifiques lors de la prochaine conférence PAINWeek 2025, mettant en avant des données issues de son programme de Phase 3 pour une nouvelle formulation de méloxicam à action rapide (MR-107A-02) dans le traitement de la douleur chirurgicale aiguë modérée à sévère.

Les présentations, prévues du 2 au 5 septembre 2025 à Las Vegas, présenteront les résultats de deux études clés sur des modèles chirurgicaux d’herniorraphie et de bunionectomie. Les données incluent la pharmacocinétique, l’efficacité, la sécurité et la réduction de l’utilisation des opioïdes. Quatre résumés seront présentés en direct le 4 septembre, tandis qu’un sera uniquement présenté sous forme de poster.

Viatris (Nasdaq: VTRS) gab die Präsentation von fünf wissenschaftlichen Abstracts auf der bevorstehenden PAINWeek 2025 Konferenz bekannt, bei der Daten aus dem Phase-3-Programm für eine neuartige schnellwirkende Meloxicam-Formulierung (MR-107A-02) zur Behandlung von mittelschweren bis schweren akuten Operationsschmerzen vorgestellt werden.

Die Präsentationen, die vom 2. bis 5. September 2025 in Las Vegas stattfinden, zeigen Ergebnisse aus zwei entscheidenden Studien an Herniorrhaphie- und Hallux-valgus-Operationsmodellen. Die Daten umfassen Pharmakokinetik, Wirksamkeit, Sicherheit und Reduktion des Opioidgebrauchs. Vier Abstracts werden am 4. September live präsentiert, eines wird ausschließlich als Poster gezeigt.

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Insights

Viatris' positive Phase 3 results for fast-acting meloxicam show promise for reducing opioid use in post-surgical pain management.

Viatris is advancing its novel fast-acting meloxicam formulation (MR-107A-02) with positive Phase 3 results to be presented at PAINWeek 2025. The data comes from two pivotal studies in herniorrhaphy (hernia repair) and bunionectomy surgical models, indicating the company has reached a significant clinical development milestone.

The presentation of five different abstracts demonstrates a comprehensive data package, covering efficacy, safety, pharmacokinetics, and importantly, opioid-sparing effects. This last point is particularly significant as finding effective non-opioid pain management options remains a major unmet need in addressing the ongoing opioid crisis.

Fast-acting NSAIDs like this meloxicam formulation represent an important advancement over traditional NSAIDs, which typically have slower onset of action. The pharmacokinetic data being presented will likely highlight how this formulation achieves more rapid absorption compared to standard meloxicam (Mobic®), potentially offering quicker pain relief in acute surgical settings.

The fact that Viatris specifically notes "positive results" suggests the drug met its primary endpoints in these trials, though specific efficacy metrics aren't disclosed in this announcement. The company's comprehensive approach to data presentation � spanning multiple posters addressing different aspects of the drug's profile � indicates confidence in the overall clinical package and suggests they're positioning this product for regulatory submission.

Presentations to include efficacy, safety and opioid use reduction data in two different surgery models as well as pharmacokinetics data

PITTSBURGH, Aug. 1, 2025 /PRNewswire/ -- (Nasdaq: VTRS), a global healthcare company, today announced that five abstracts from its Phase 3 program evaluating novel fast-acting formulation of meloxicam (MR-107A-02) in moderate-to-severe acute surgical pain models will be presented at the PAINWeek 2025 national conference in Las Vegas from September 2-5, 2025.

The presentations will include positive results from two previously announced pivotal studies in herniorrhaphy (NCT06215859) and bunionectomy (NCT06215820) surgery models. All accepted scientific abstracts are now available on the .

Full List of Viatris Presentations at PAINWeek 2025

Poster Title

Presentation Details

Poster #41

Pharmacokinetics study comparing MR-107A-02 (novel fast-acting

meloxicam formulation) 15mg tablet with meloxicam (Mobic®)

15mg in healthy adult male subjects.

Live Abstract Presentation

Thursday, Sept. 4

4:35 p.m. - 4:45 p.m. PDT

Poster #39

Efficacy and safety of MR-107A-02 (novel fast-acting meloxicam

formulation) for the treatment of acute moderate-to-severe pain

following bunionectomy

Live Abstract Presentation

Thursday, Sept. 4

4:50 p.m. - 5:00 p.m. PDT

Poster #38

Efficacy and safety of MR-107A-02 (novel meloxicam fast-acting

formulation) for the treatment of acute moderate-to-severe pain

following herniorrhaphy.

Live Abstract Presentation

Thursday, Sept. 4

5:05 p.m. - 5:15 p.m. PDT

Poster #40

Opioid sparing effect of MR-107A-02 (novel fast-acting meloxicam

formulation) for the treatment of acute moderate-to-severe pain

followingbunionectomy and herniorrhaphy.

Live Abstract Presentation

Thursday, Sept. 4

5:20 p.m. - 5:30 p.m. PDT

Poster #76

Efficacy and Safety of a Rapid-Absorption Formulation of

Meloxicam in the Treatment of Acute Postoperative Pain Following

Bunionectomy and Herniorrhaphy

Poster presentation only

AboutViatris
(Nasdaq: VTRS) is a global healthcare company uniquely positioned to bridge the traditional divide between generics and brands, combining the best of both to more holistically address healthcare needs globally. With a mission to empower people worldwide to live healthier at every stage of life, we provide access at scale, currently supplying high-quality medicines to approximately 1 billion patients around the world annually and touching all of life's moments, from birth to the end of life, acute conditions to chronic diseases. With our exceptionally extensive and diverse portfolio of medicines, a one-of-a-kind global supply chain designed to reach more people when and where they need them, and the scientific expertise to address some of the world's most enduring health challenges, access takes on deep meaning at Viatris. We are headquartered in the U.S., with global centers in Pittsburgh, Shanghai andHyderabad, India. Learn more at and, and connect with us on,,and.

Forward-Looking Statements
This press release includes statements that constitute "forward-looking statements." These statements are made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. Such forward-looking statements may include statements that about the results of clinical trials. Because forward-looking statements inherently involve risks and uncertainties, actual future results may differ materially from those expressed or implied by such forward-looking statements. Factors that could cause or contribute to such differences include, but are not limited to: the uncertainties inherent in research and development, including the outcomes of clinical trials; the ability to meet anticipated clinical endpoints; the possibility of unfavorable new clinical data and further analyses of existing clinical data; the risk that clinical trial data are subject to differing interpretations and assessments by regulatory authorities; whether regulatory authorities will be satisfied with the design of and results from clinical studies; actions and decisions of healthcare and pharmaceutical regulators; our ability to comply with applicable laws and regulations; changes in healthcare and pharmaceutical laws and regulations in the U.S. and abroad; any regulatory, legal or other impediments to Viatris' ability to bring new products to market; products in development and/or that receive regulatory approval may not achieve expected levels of market acceptance, efficacy or safety; longer review, response and approval times as a result of evolving regulatory priorities and reductions in personnel at health agencies; Viatris' or its partners' ability to develop, manufacture, and commercialize products; the scope, timing and outcome of any ongoing legal proceedings, and the impact of any such proceedings on Viatris; Viatris' failure to achieve expected or targeted future financial and operating performance and results; goodwill or impairment charges or other losses; any changes in or difficulties with the Company's manufacturing facilities; risks associated with international operations; changes in third-party relationships; the effect of any changes in Viatris' or its partners' customer and supplier relationships and customer purchasing patterns; the impacts of competition; changes in the economic and financial conditions of Viatris or its partners; uncertainties regarding future demand, pricing and reimbursement for the Company's products; uncertainties and matters beyond the control of management, including but not limited to general political and economic conditions, potential adverse impacts from future tariffs and trade restrictions, inflation rates and global exchange rates; and the other risks described in Viatris' filings with the Securities and Exchange Commission ("SEC"). Viatris routinely uses its website as a means of disclosing material information to the public in a broad, non-exclusionary manner for purposes of the SEC's Regulation Fair Disclosure (Reg FD). Viatris undertakes no obligation to update these statements for revisions or changes after the date of this press release other than as required by law.

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FAQ

When will Viatris (VTRS) present its meloxicam data at PAINWeek 2025?

Viatris will present four live abstracts on Thursday, September 4, 2025, between 4:35 PM and 5:30 PM PDT, plus one poster presentation at the PAINWeek 2025 conference in Las Vegas.

What clinical trials will Viatris present data from at PAINWeek 2025?

Viatris will present data from two pivotal Phase 3 studies: the herniorrhaphy trial (NCT06215859) and bunionectomy trial (NCT06215820), evaluating their novel fast-acting meloxicam formulation (MR-107A-02).

What types of data will be presented in Viatris's PAINWeek 2025 abstracts?

The presentations will cover pharmacokinetics, efficacy, safety, and opioid use reduction data for MR-107A-02 in treating moderate-to-severe acute surgical pain.

How many abstracts will Viatris present at PAINWeek 2025?

Viatris will present five total abstracts, including four live abstract presentations and one poster presentation.
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