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Arcturus Therapeutics Holdings Inc. (Nasdaq: ARCT) has furnished an 8-K under Item 7.01 to disclose positive interim Phase 2 results for its mRNA candidate ARCT-810, which is being developed to treat ornithine transcarbamylase (OTC) deficiency. The company states that the investigational therapy is designed to replace the OTC enzyme and restore urea-cycle function, thereby preventing hyperammonemia crises in affected patients.
- A press release detailing the data and a webcast presentation were released on 30 Jun 2025 and are attached as Exhibits 99.1 and 99.2.
- The disclosure is furnished�not filed—under Regulation FD; therefore, it carries no Section 18 liability and will not be incorporated by reference into future SEC filings.
- No financial statements, earnings figures, or transaction details are included.
The filing underscores continued progress in Arcturus’s rare-disease pipeline and may influence investor sentiment pending full Phase 2 data and eventual pivotal trials.