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Zentalis Pharmaceuticals, Inc. SEC Filings

ZNTL NASDAQ

Welcome to our dedicated page for Zentalis Pharmaceuticals SEC filings (Ticker: ZNTL), a comprehensive resource for investors and traders seeking official regulatory documents including 10-K annual reports, 10-Q quarterly earnings, 8-K material events, and insider trading forms.

Parsing Zentalis Pharmaceuticals� disclosures is no small task—each 10-K details years of oncology R&D on its lead WEE1 inhibitor, azenosertib, alongside complex milestone obligations and dilution risks. If you have ever tried to locate trial spend or option-exercise clauses buried in hundreds of pages, you know the challenge of Zentalis SEC filings explained simply.

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Rhea-AI Summary

Zentalis Pharmaceuticals (ZNTL) Director Luke Nathaniel Walker received a grant of 57,603 restricted stock units (RSUs) on June 17, 2025, as part of the company's Non-Employee Director Compensation Program. Following this transaction, Walker's direct ownership increased to 144,284 shares.

Key details of the RSU grant:

  • Each RSU represents a contingent right to receive one share of common stock
  • Vesting occurs at the earlier of June 17, 2026, or the next annual stockholder meeting
  • Vesting is contingent on continued service on the Board of Directors
  • The RSUs were granted at $0 cost to the director

The transaction was reported via Form 4 filing and was executed through an attorney-in-fact, Andrea Paul, on June 18, 2025. This equity grant aligns with standard director compensation practices and serves to strengthen the alignment between director and shareholder interests.

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Zentalis Pharmaceuticals (ZNTL) Director Jan Skvarka received a grant of 57,603 restricted stock units (RSUs) on June 17, 2025, as part of the company's Non-Employee Director Compensation Program. Following this transaction, Skvarka now beneficially owns 207,154 shares directly.

Key details of the RSU grant:

  • Each RSU represents a contingent right to receive one share of common stock
  • Vesting occurs at the earlier of June 17, 2026 or the next annual stockholder meeting
  • Vesting is contingent on continued service on the Board of Directors
  • The RSUs were granted at $0 exercise price

This Form 4 filing was submitted by Andrea Paul as attorney-in-fact for Jan Skvarka on June 18, 2025, in compliance with SEC insider trading reporting requirements.

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Zentalis Pharmaceuticals (ZNTL) Director David Michael Johnson reported acquiring 57,603 restricted stock units (RSUs) on June 17, 2025. The RSUs were granted under the company's Non-Employee Director Compensation Program at a price of $0.

Key details of the transaction:

  • Following the transaction, Johnson directly owns 250,421 shares
  • The RSUs will vest on the earlier of June 17, 2026 or the next annual stockholder meeting
  • Vesting is contingent on Johnson's continued service on the Board of Directors
  • Each RSU represents the right to receive one share of common stock upon vesting

The Form 4 was filed on June 28, 2025, with the signature executed by Andrea Paul as attorney-in-fact for David M. Johnson on June 18, 2025.

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Zentalis Pharmaceuticals (NASDAQ: ZNTL) held its 2025 Annual Meeting of Stockholders on June 17, with 80.9% of outstanding shares represented. Key voting results include:

  • Director Elections: Three Class II directors were elected to serve until 2028: - Scott Myers (43M votes for) - Karan Takhar (30.7M votes for) - Luke Walker, M.D. (36.6M votes for)
  • Auditor Ratification: Ernst & Young LLP appointment was approved with overwhelming support (58.1M votes for, representing 99.8% approval)
  • Executive Compensation: The "Say-on-Pay" vote passed but with significant opposition - 62.9% in favor (29.5M votes) versus 37.1% against (17.4M votes), indicating substantial shareholder concerns about executive compensation practices

The meeting results suggest strong shareholder engagement but reveal notable dissent regarding executive compensation and varying levels of support for board nominees, particularly for Karan Takhar who received the lowest approval rate among directors.

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FAQ

What is the current stock price of Zentalis Pharmaceuticals (ZNTL)?

The current stock price of Zentalis Pharmaceuticals (ZNTL) is $1.24 as of July 2, 2025.

What is the market cap of Zentalis Pharmaceuticals (ZNTL)?

The market cap of Zentalis Pharmaceuticals (ZNTL) is approximately 94.3M.

What is the primary focus of Zentalis Pharmaceuticals?

Zentalis Pharmaceuticals is concentrated on discovering and developing novel small molecule therapeutics targeting fundamental cancer pathways, particularly focusing on cell cycle and DNA repair mechanisms.

What role does the Integrated Discovery Engine play in their operations?

The Integrated Discovery Engine is central to Zentalis� strategy, enabling the identification of key therapeutic targets and the development of new chemical entities designed to exhibit differentiated profiles against cancer.

What is azenosertib and how is it significant?

Azenosertib is Zentalis� lead product candidate and a potent, selective WEE1 inhibitor that aims to exploit vulnerabilities in cancer cells by interfering with cell cycle checkpoints, and is being evaluated as both a monotherapy and in combination treatments.

Which types of cancers are being targeted by Zentalis� clinical programs?

Their clinical programs span a range of cancers, including advanced solid tumors, gynecological malignancies, and hematologic cancers, with tailored clinical trials to assess efficacy in these diverse settings.

How does the company utilize biomarker-enrichment strategies?

Zentalis employs biomarker-enrichment tactics, such as assessing Cyclin E1 expression, to identify patient subgroups most likely to respond to therapy, thereby enhancing the precision and impact of their clinical trials.

How does Zentalis differentiate itself in the competitive oncology landscape?

By leveraging its proprietary Integrated Discovery Engine and a focused research strategy on fundamental biological pathways, Zentalis differentiates itself through a deep understanding of cancer biology and targeted therapeutic development.

What are the key advantages of small molecule therapeutics developed by Zentalis?

Small molecule therapeutics offer the benefits of oral bioavailability, potential for precise targeting of oncogenic pathways, and a favorable safety profile, all of which are integral to Zentalis� development approach.

What insights can investors gain from Zentalis� clinical trial progress?

Investors can learn about the robustness of Zentalis� clinical programs, the scientific rationale behind their therapeutic candidates, and the company’s methodical approach to translating preclinical findings into potential patient benefits.
Zentalis Pharmaceuticals, Inc.

NASDAQ:ZNTL

ZNTL Rankings

ZNTL Stock Data

94.26M
61.83M
15.58%
93.52%
7.26%
Biotechnology
Pharmaceutical Preparations
United States
SAN DIEGO