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Hemogenyx Pharmaceuticals PLC Announces Placing to Raise £250,000 and Director's Dealing

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Hemogenyx Pharmaceuticals (OTC:HOPHF) has secured £250,000 through a strategic share placement, issuing 133,690 new ordinary shares at 187p per share, representing a premium to the current market price. The shares will be initially allotted to CEO Vladislav Sandler, who will then transfer them to a group of new investors.

The funding will support the continuation of the company's Phase I clinical trials for HG-CT-1, their Chimeric Antigen Receptor T-cell therapy targeting relapsed/refractory acute myeloid leukemia in adults. The company reports that the first two patients have completed four-week safety trials with encouraging early efficacy signs.

The deal includes one-for-one warrants exercisable at 187p for 36 months. Upon admission of the new shares, expected around August 7, 2025, the total number of issued shares will be 4,727,229.

Hemogenyx Pharmaceuticals (OTC:HOPHF) ha ottenuto £250.000 tramite un collocamento strategico di azioni, emettendo 133.690 nuove azioni ordinarie a 187p per azione, rappresentando un premio rispetto al prezzo di mercato attuale. Le azioni saranno inizialmente assegnate al CEO Vladislav Sandler, che poi le trasferirà a un gruppo di nuovi investitori.

I fondi sosterranno la prosecuzione degli studi clinici di Fase I per HG-CT-1, la loro terapia con cellule T a recettore antigene chimerico (CAR-T) rivolta alla leucemia mieloide acuta recidivante/refrattaria negli adulti. L'azienda riferisce che i primi due pazienti hanno completato le prove di sicurezza di quattro settimane con segnali iniziali di efficacia promettenti.

L'accordo include warrant uno a uno esercitabili a 187p per 36 mesi. Con l'ammissione delle nuove azioni, prevista intorno al 7 agosto 2025, il numero totale di azioni emesse sarà 4.727.229.

Hemogenyx Pharmaceuticals (OTC:HOPHF) ha asegurado £250,000 a través de una colocación estratégica de acciones, emitiendo 133,690 nuevas acciones ordinarias a 187p por acción, lo que representa una prima sobre el precio actual de mercado. Las acciones serán inicialmente asignadas al CEO Vladislav Sandler, quien luego las transferirá a un grupo de nuevos inversores.

Los fondos apoyarán la continuación de los ensayos clínicos de Fase I para HG-CT-1, su terapia con células T de receptor de antígeno quimérico dirigida a la leucemia mieloide aguda recidivante/refractaria en adultos. La compañía informa que los primeros dos pacientes han completado ensayos de seguridad de cuatro semanas con señales tempranas alentadoras de eficacia.

El acuerdo incluye warrants uno a uno ejercitables a 187p por 36 meses. Tras la admisión de las nuevas acciones, prevista alrededor del 7 de agosto de 2025, el número total de acciones emitidas será de 4,727,229.

Hemogenyx Pharmaceuticals (OTC:HOPHF)� 전략� 주식 배정� 통해 25� 파운드를 확보했으�, 주당 187펜스� 133,690주의 보통주를 신규 발행했습니다. 이는 현재 시장 가격에 대� 프리미엄� 의미합니�. 주식은 최초� CEO 블라디슬라브 샌들러에� 배정되며, 이후 그는 이를 신규 투자� 그룹� 이전� 예정입니�.

이번 자금은 성인 재발/불응� 급성 골수� 백혈병을 표적으로 하는 키메� 항원 수용� T세포 치료제인 HG-CT-1� 1� 임상 시험 지속을 지원할 것입니다. 회사� � � 환자가 4주간� 안전� 시험� 마쳤으며 초기 효능 징후가 고무적이라고 보고했습니다.

이번 거래에는 36개월 동안 행사 가능한 주당 187펜스� 1대1 워런트가 포함되어 있습니다. 신규 주식 상장은 2025� 8� 7일경으로 예상되며, � 발행 주식 수는 4,727,229�가 � 것입니다.

Hemogenyx Pharmaceuticals (OTC:HOPHF) a levé 250 000 £ via un placement stratégique d'actions, émettant 133 690 nouvelles actions ordinaires à 187p par action, représentant une prime par rapport au cours actuel du marché. Les actions seront initialement attribuées au PDG Vladislav Sandler, qui les transférera ensuite à un groupe de nouveaux investisseurs.

Ce financement soutiendra la poursuite des essais cliniques de phase I pour HG-CT-1, leur thérapie par cellules T à récepteur antigénique chimérique ciblant la leucémie myéloïde aiguë récidivante/réfractaire chez l'adulte. La société rapporte que les deux premiers patients ont terminé les essais de sécurité de quatre semaines avec des signes précoces d'efficacité encourageants.

L'accord comprend des bons de souscription un pour un exerçables à 187p pendant 36 mois. Lors de l'admission des nouvelles actions, prévue aux alentours du 7 août 2025, le nombre total d'actions émises sera de 4 727 229.

Hemogenyx Pharmaceuticals (OTC:HOPHF) hat durch eine strategische Aktienplatzierung 250.000 £ eingenommen und dabei 133.690 neue Stammaktien zu je 187 Pence ausgegeben, was einen Aufschlag auf den aktuellen Marktpreis darstellt. Die Aktien werden zunächst dem CEO Vladislav Sandler zugeteilt, der sie anschließend an eine Gruppe neuer Investoren übertragen wird.

Die Finanzierung unterstützt die Fortsetzung der Phase-I-Studien für HG-CT-1, ihre chimäre Antigenrezeptor-T-Zelltherapie zur Behandlung von rezidivierender/refraktärer akuter myeloischer Leukämie bei Erwachsenen. Das Unternehmen berichtet, dass die ersten beiden Patienten die vierwöchigen Sicherheitstests abgeschlossen haben und ermutigende erste Anzeichen für Wirksamkeit gezeigt wurden.

Der Deal umfasst Ein-zu-eins-Warrants, die zu 187 Pence für 36 Monate ausübbar sind. Mit der Zulassung der neuen Aktien, die voraussichtlich um den 7. August 2025 erfolgt, wird die Gesamtzahl der ausgegebenen Aktien 4.727.229 betragen.

Positive
  • Successful fundraising of £250,000 at a premium to market price
  • Positive early efficacy signs from first two patients in Phase I trials
  • Successful completion of four-week safety trials for HG-CT-1
  • Additional potential funding through warrant exercise at 187p per share
Negative
  • Small fundraising amount may require additional capital raises
  • Complex share issuance structure required due to prospectus regulations
  • Warrant exercise price reset clause could lead to potential dilution

THIS ANNOUNCEMENT CONTAINS INSIDE INFORMATION AS STIPULATED UNDER THE UK VERSION OF THE MARKET ABUSE REGULATION NO 596/2014 WHICH IS PART OF ENGLISH LAW BY VIRTUE OF THE EUROPEAN (WITHDRAWAL) ACT 2018, AS AMENDED. ON PUBLICATION OF THIS ANNOUNCEMENT VIA A REGULATORY INFORMATION SERVICE, THIS INFORMATION IS CONSIDERED TO BE IN THE PUBLIC DOMAIN.

Hemogenyx Secures £250,000 to continue its Phase 1 Clinical Trials And Director's Dealing

LONDON, UK / / July 29, 2025 /

Introduction

Hemogenyx Pharmaceuticals plc (LSE:HEMO) is pleased to announce that it has raised gross proceeds of £250,000 via an allotment to Vladislav Sandler of 133,690 new ordinary shares of £0.01 each ("New Ordinary Shares") at an issue price of 187p, representing a premium to the present market price (the "Issue Price").

The net proceeds of this fundraise will be dedicated to the continuation of the Phase I clinical trials for the Company's Chimeric Antigen Receptor T-cell therapy ("HG-CT-1"), aimed at treating relapsed/refractory acute myeloid leukemia in adults ("R/R AML"). As shareholders will be aware, the first two patients have now been treated with HG-CT-1 with the four-week safety trials successfully completed and with encouraging early signs of efficacity.

Issuance of the New Ordinary Shares

The Company is currently unable to issue and admit New Ordinary Shares without either the publication of an FCA approved prospectus or relying upon an exemption to the requirement to issue a prospectus.

Consequently, this fundraise involves the agreement by Vladislav Sandler, CEO and director of the Company, to subscribe for the New Ordinary Shares at the Issue Price pursuant to the employee offer exemption under Article 1(4)(i) and 1(5) (h) of the UK Prospectus Regulation.

Following allotment of the New Ordinary Shares, Vladislav Sandler has agreed to direct their issue to a small group of individual investors who made an approach wishing to make a new investment in the Company; they will acquire the Subscription Shares from Mr Sandler at the price of 187p per share.

Warrants

Concurrent with the purchase of the New Ordinary Shares, the new investor group will receive warrants from the Company on a one-for-one basis. These warrants will be exercisable for a period of 36 months at an exercise price of 187p ("Exercise Price"), subject to adjustment in certain circumstances as set out in the warrant instrument including a reset of the Exercise Price if the Company completes a share issuance (or other transaction granting rights to subscribe for equity securities) during the Exercise Period at a price lower than the Exercise Price.

Total Voting Rights

Application will be made for the 133,690 New Ordinary Shares, which will rank pari passu in all respects with the existing Ordinary Shares of the Company, to be admitted to theFCA official list and to trading on the equity shares (transition) category of the Official List maintained by the FCA and to trading on the main market for listed securities of the LSE, which is expected to occur on or around 8.00 a.m. on 7 August 2025 ("Admission").

Upon Admission, the total number of issued shares and the total number of voting rights in the Company will be 4,727,229.

​The above figure of 4,727,229 should be used by shareholders in the Company as the denominator for the calculations by which they will determine if they are required to notify their interest in, or a change to their interest in, the share capital of the Company under the Financial Conduct Authority's Disclosure Guidance and Transparency Rules.

The Company will keep the market informed of future developments as trials proceed.

Dr Vladislav Sandler, CEO & Co-Founder of Hemogenyx Pharmaceuticals, commented:
"We are pleased to have attracted funding from this group of investors at a premium to the current price - this reflects their confidence in the progress made by the Company to date and in the long-term prospects of Hemogenyx. The fact that the raise was completed at a premium to the market price demonstrates this confidence and shows that they see considerable upside potential in our share price as we advance HG-CT-1 through clinical development. ."


UK Market Abuse Regulation (UK MAR) Disclosure

Certain information contained in this announcement would have been inside information for the purposes of Article 7 of Regulation No 596/2014 (as it forms part of UK domestic law by virtue of the European Union (Withdrawal) Act 2018) until the release of this announcement. The person responsible for arranging for the release of this announcement on behalf of Hemogenyx Pharmaceuticals plc is Dr Vladislav Sandler, Chief Executive Officer & Co-Founder.

Director's Dealing Notification

1.

Details of the person discharging managerial responsibilities / person closely associated

a)

Name

Vladislav Sandler

2.

Reason for the Notification

a)

Position/status

PDMR

b)

Initial notification / Amendment

Initial notification

3.

Details of the issuer, emission allowance market participant, auction platform, auctioneer or auction monitor

a)

Name

Hemogenyx Pharmaceuticals plc

b)

LEI

2138008L93GYU5GN6179

4.

Details of the transaction(s): section to be repeated for (i) each type of instrument; (ii) each type of transaction; (iii) each date; and (iv) each place where transactions have been conducted

a)

Description of the Financial instrument, type of instrument

Ordinary Shares of £0.01

Identification Code

GB00BQVXM815

b)

Nature of the transaction

Off Market Allotment

c)

Price(s) and volume(s)

Price(s)

Volume(s)

187 pence per Ordinary Share

133,690 Ordinary Shares

d)

Aggregated information:

Aggregated volume

Price

133,690 Ordinary Shares

187 pence per Ordinary Share

e)

Date of the transaction

29 July 2025

f)

Place of the transaction

London

Enquiries:

Hemogenyx Pharmaceuticals plc

Dr Vladislav Sandler, Chief Executive Officer & Co-Founder

[email protected]

Peter Redmond, Director

[email protected]

SP Angel Corporate Finance LLP

Tel: +44 (0)20 3470 0470

Matthew Johnson, Vadim Alexandre, Adam Cowl

Peterhouse Capital Limited

Tel: +44 (0)20 7469 0930

Lucy Williams, Duncan Vasey, Charles Goodfellow

About Hemogenyx Pharmaceuticals plc

Hemogenyx Pharmaceuticals is a publicly traded company (LSE: HEMO) headquartered in London, with its US operating subsidiaries, Hemogenyx Pharmaceuticals LLC and Immugenyx LLC, located in New York City .

The Company is a clinical stage biopharmaceutical group developing new medicines and treatments to treat blood and autoimmune diseases. Hemogenyx Pharmaceuticals is developing several distinct and complementary product candidates, as well as platform technologies that it uses as engines for novel product development.

This information is provided by RNS, the news service of the London Stock Exchange. RNS is approved by the Financial Conduct Authority to act as a Primary Information Provider in the United Kingdom. Terms and conditions relating to the use and distribution of this information may apply. For further information, please contact [email protected] or visit .

SOURCE: Hemogenyx Pharmaceuticals PLC



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FAQ

How much did Hemogenyx Pharmaceuticals (HOPHF) raise in the July 2025 placement?

Hemogenyx raised £250,000 through the issuance of 133,690 new ordinary shares at 187p per share, at a premium to the market price.

What is the current status of Hemogenyx's HG-CT-1 clinical trials?

The Phase I clinical trials have shown encouraging early efficacy signs, with the first two patients successfully completing their four-week safety trials.

What are the terms of the warrants issued with Hemogenyx's July 2025 placement?

The warrants are issued on a one-for-one basis, exercisable for 36 months at 187p per share, with a price reset provision if the company issues shares at a lower price during the exercise period.

How many shares will Hemogenyx Pharmaceuticals have outstanding after the July 2025 placement?

Following the admission of the new shares, Hemogenyx will have 4,727,229 total outstanding shares.

What will Hemogenyx use the proceeds from the July 2025 placement for?

The proceeds will be used to continue Phase I clinical trials for HG-CT-1, their CAR-T cell therapy targeting relapsed/refractory acute myeloid leukemia in adults.
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