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LakeShore Biopharma Announces Fiscal Year 2025 Financial Results

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LakeShore Biopharma (NASDAQ:LSB) reported its FY2025 financial results, showing mixed performance with improvements in profitability despite missing guidance targets. Total revenue increased 7.2% to RMB615.0 million, while gross profit rose 11.3% to RMB507.2 million with improved margins of 82.5%.

The company significantly narrowed its net loss to RMB100.0 million from RMB433.5 million in FY2024, while operating expenses decreased by 34.2%. Their flagship product, YSJATM rabies vaccine, has been administered in approximately 110 million doses and distributed to 1,911 county-level CDCs in China. The company is advancing a Phase III trial for a simplified four-dose regimen, targeting market approval by Q4 2026.

For FY2026, LSB projects revenue between RMB550-650 million, while facing challenges including intensified competition, pricing pressures, and ongoing litigation with their former Chairman affecting credit access.

LakeShore Biopharma (NASDAQ:LSB) ha comunicato i risultati finanziari per l'anno fiscale 2025, mostrando una performance mista con miglioramenti nella redditività nonostante non abbia raggiunto gli obiettivi di guidance. Il fatturato totale è aumentato del 7,2% raggiungendo 615,0 milioni di RMB, mentre il profitto lordo è cresciuto dell'11,3% arrivando a 507,2 milioni di RMB con margini migliorati all'82,5%.

L'azienda ha ridotto significativamente la perdita netta a 100,0 milioni di RMB rispetto ai 433,5 milioni di RMB dell'anno fiscale 2024, mentre le spese operative sono diminuite del 34,2%. Il prodotto di punta, il vaccino antirabbico YSJA�, è stato somministrato in circa 110 milioni di dosi e distribuito a 1.911 CDC a livello di contea in Cina. L'azienda sta portando avanti una sperimentazione di Fase III per un regime semplificato di quattro dosi, con l'obiettivo di ottenere l'approvazione di mercato entro il quarto trimestre del 2026.

Per l'anno fiscale 2026, LSB prevede un fatturato compreso tra 550 e 650 milioni di RMB, affrontando però sfide quali una concorrenza più intensa, pressioni sui prezzi e contenziosi in corso con l'ex Presidente, che influenzano l'accesso al credito.

LakeShore Biopharma (NASDAQ:LSB) reportó sus resultados financieros del año fiscal 2025, mostrando un desempeño mixto con mejoras en la rentabilidad a pesar de no alcanzar las metas de guía. Los ingresos totales aumentaron un 7,2% hasta 615,0 millones de RMB, mientras que la ganancia bruta subió un 11,3% a 507,2 millones de RMB con márgenes mejorados del 82,5%.

La compañía redujo significativamente su pérdida neta a 100,0 millones de RMB desde 433,5 millones de RMB en el año fiscal 2024, mientras que los gastos operativos disminuyeron un 34,2%. Su producto estrella, la vacuna contra la rabia YSJA�, ha sido administrada en aproximadamente 110 millones de dosis y distribuida a 1.911 CDC a nivel de condado en China. La empresa avanza en un ensayo de Fase III para un régimen simplificado de cuatro dosis, con la meta de obtener la aprobación del mercado para el cuarto trimestre de 2026.

Para el año fiscal 2026, LSB proyecta ingresos entre 550 y 650 millones de RMB, enfrentando desafíos como una competencia intensificada, presiones en los precios y litigios en curso con su ex presidente que afectan el acceso al crédito.

LakeShore Biopharma (NASDAQ:LSB)� 2025 회계연도 재무 실적� 발표했으�, 가이던� 목표에는 미치지 못했지� 수익성은 개선� 혼재� 성과� 보였습니�. � 매출은 7.2% 증가� 6� 1,500� 위안� 기록했고, 총이익은 11.3% 증가� 5� 720� 위안으로 마진� 82.5%� 향상되었습니�.

회사� 2024 회계연도� 4� 3,350� 위안 순손실에� 1� 위안으로 순손실을 크게 줄였으며, 영업비용은 34.2% 감소했습니다. 주력 제품� YSJA� 광견� 백신은 � 1� 1천만 도즈가 투여되었� 중국 � 1,911� � CDC� 배포되었습니�. 회사� 간소화된 4� 접종 요법� 대� 3� 임상� 진행 중이�, 2026� 4분기 시장 허가� 목표� 하고 있습니다.

2026 회계연도에는 LSB가 5� 5,000만~6� 5,000� 위안� 매출� 예상하고 있으�, 경쟁 심화, 가� 압박, � 회장과의 지� 중인 소송으로 인한 신용 접근� 문제 � 여러 도전� 직면� 있습니다.

LakeShore Biopharma (NASDAQ:LSB) a publié ses résultats financiers pour l'exercice 2025, affichant une performance mitigée avec des améliorations de la rentabilité malgré un non-respect des objectifs prévus. Le chiffre d'affaires total a augmenté de 7,2 % pour atteindre 615,0 millions de RMB, tandis que le bénéfice brut a progressé de 11,3 % à 507,2 millions de RMB avec une marge améliorée de 82,5 %.

L'entreprise a considérablement réduit sa perte nette à 100,0 millions de RMB contre 433,5 millions de RMB en 2024, tandis que les charges d'exploitation ont diminué de 34,2 %. Leur produit phare, le vaccin antirabique YSJA�, a été administré à environ 110 millions de doses et distribué à 1 911 CDC au niveau des comtés en Chine. La société fait progresser un essai de phase III pour un schéma simplifié en quatre doses, visant une approbation du marché d'ici le quatrième trimestre 2026.

Pour l'exercice 2026, LSB prévoit un chiffre d'affaires compris entre 550 et 650 millions de RMB, tout en faisant face à des défis tels qu'une concurrence accrue, des pressions sur les prix et des litiges en cours avec leur ancien président, affectant l'accès au crédit.

LakeShore Biopharma (NASDAQ:LSB) veröffentlichte seine Finanzergebnisse für das Geschäftsjahr 2025 und zeigte eine gemischte Leistung mit Verbesserungen in der Rentabilität, obwohl die Prognoseziele verfehlt wurden. Der Gesamtumsatz stieg um 7,2 % auf 615,0 Millionen RMB, während der Bruttogewinn um 11,3 % auf 507,2 Millionen RMB mit verbesserten Margen von 82,5 % zunahm.

Das Unternehmen verringerte seinen Nettoverlust deutlich auf 100,0 Millionen RMB von 433,5 Millionen RMB im Geschäftsjahr 2024, während die Betriebskosten um 34,2 % sanken. Ihr Flaggschiffprodukt, der YSJA� Tollwutimpfstoff, wurde in etwa 110 Millionen Dosen verabreicht und an 1.911 CDC auf Kreisebene in China verteilt. Das Unternehmen führt eine Phase-III-Studie für ein vereinfachtes Vier-Dosen-Regime durch und strebt eine Marktzulassung bis zum vierten Quartal 2026 an.

Für das Geschäftsjahr 2026 prognostiziert LSB einen Umsatz zwischen 550 und 650 Millionen RMB, sieht sich jedoch Herausforderungen wie verstärktem Wettbewerb, Preisdruck und laufenden Rechtsstreitigkeiten mit dem ehemaligen Vorsitzenden gegenüber, welche den Zugang zu Krediten beeinträchtigen.

Positive
  • Net loss significantly narrowed by 77% year-over-year to RMB100.0 million
  • Gross margin improved to 82.5% from 79.5% in previous year
  • Total operating expenses decreased 34.2% year-over-year
  • YSJATM rabies vaccine achieved 67.7% coverage across Chinese CDCs
  • R&D expenses decreased significantly due to completed trials and cost optimization
Negative
  • Failed to meet revenue guidance of RMB665-700 million
  • Missed adjusted EBITDA guidance range of RMB76-89 million
  • Cash and equivalents decreased to RMB107.5M from RMB246.6M year-over-year
  • Short-term loans increased to RMB390.4M from RMB318.5M
  • Ongoing litigation with former Chairman limiting access to new credit lines

Insights

LakeShore Biopharma shows significant financial improvement with narrowing losses despite missing guidance targets.

LakeShore Biopharma's FY2025 results present a company making substantial progress toward profitability despite falling short of guidance targets. The 7.2% revenue growth to RMB615.0 million and more impressive 11.3% increase in gross profit to RMB507.2 million demonstrate strengthening core business performance. Most notable is the 77% reduction in net loss year-over-year, shrinking from RMB433.5 million to RMB100.0 million.

The improved gross margin of 82.5% (up from 79.5%) reveals effective pricing strategy and cost management. The company has made remarkable progress on expense control, with total operating expenses decreasing by 34.2% year-over-year to RMB593.5 million. This disciplined approach spans across departments: S&M expenses down 6.6%, G&A expenses reduced by 7.9%, and R&D costs cut by over half.

However, investors should note the company missed both revenue and adjusted EBITDA guidance. The company cited increased competition in the rabies vaccine market, pricing pressures, distribution channel limitations, and ongoing cash constraints due to litigation with its former Chairman as contributing factors.

The balance sheet shows declining cash reserves of RMB107.5 million (down from RMB246.6 million) and increased short-term borrowings at RMB390.4 million (up from RMB318.5 million), indicating potential liquidity challenges ahead. The FY2026 revenue guidance of RMB550-650 million suggests uncertainty, with the low end representing a potential revenue decline.

While the company's YSJATM rabies vaccine maintains strong market presence with distribution to 67.7% of county-level CDCs in China, future growth heavily depends on obtaining approval for the simplified four-dose regimen in late 2026 and executing the five-point strategy outlined by management to maintain market share amidst increasing competition.

  • Total revenue reached RMB615.0 million, representing 7.2% year-over-year growth
  • Gross profit rose to RMB507.2 million, up 11.3% year-over-year
  • Gross margin improved to 82.5% from 79.5% in Fiscal Year 2024
  • Total operating expenses decreased 34.2% year-over-year to RMB593.5 million
  • EBITDA[1] and Adjusted EBITDA[2] were RMB(48.5 million) and RMB0.6 million, respectively, compared to RMB(368.7 million) and RMB(236.4 million) in Fiscal Year 2024
  • Net loss narrowed to RMB100.0 million, with an adjusted net loss[3] of RMB40.0 million, compared to RMB433.5 million and RMB266.3 million, respectively, in Fiscal Year 2024

BEIJING, July 31, 2025 /PRNewswire/ -- LakeShore Biopharma Co., Ltd (Nasdaq: LSB) ("LakeShore Biopharma" or the "Company"), a global biopharmaceutical company dedicated to discovering, developing, manufacturing, and delivering new generations of vaccines and therapeutic biologics for infectious diseases and cancer, today announced its financial results for the Fiscal Year ended March 31, 2025 ("FY2025").

"We are pleased to announce LakeShore Biopharma's FY2025 financial results with a 7.2% year-over-year growth in revenues and an 11.3% year-over-year growth in gross profits. Our net loss narrowed by 77% year-over-year", stated Xu Wang, Director and Chief Executive Officer. "While we didn't meet the revenue guidance of RMB665-700 million and our adjusted EBITDA guidance range of RMB76-89 million, we have achieved significantly improved results compared to last year, despite substantial challenges. These include intensified competition in the rabies vaccine industry market, particularly in the second half of Fiscal Year 2025, pricing pressures in certain regions, limited capacity of major vaccine distribution channels to absorb new inventories, and ongoing cash constraints stemming from our inability to secure new bank credit lines due to the ongoing litigation with former Chairman, Mr. Yi Zhang.

Mr. Xu Wang further commented: "Looking forward, we will strategically allocate our resources to maximize the commercial value of our flagship product, YSJATM rabies vaccine. Specifically, we will strive to maintain and grow our market share through the following measures: 1) expanding our coverage regions; 2) retaining and attracting high-performing CSOs; 3) driving end-market demand through collaboration with hospitals and clinics; 4) continuing to train and recruit new commercial talents; and 5) advancing the Phase III trial of the simplified four-dose regimen for the YSJATM rabies vaccine at full speed, with the goal of securing the market approval by the fourth quarter of 2026. Additionally, we will continue to enhance operational efficiency, reinforce cost control measures, and strengthen internal corporate governance."

Business Updates

YSJATM Rabies Vaccine

LakeShore Biopharma's YSJATM rabies vaccine is China's first aluminum-free lyophilized rabies vaccine (Vero cell) and has been in clinical use for over 22 years. As of March 31, 2025, approximately 110 million doses have been administered for post-exposure protection against rabies. Leveraging LakeShore Biopharma's successful commercialization capabilities, the YSJATM rabies vaccine has demonstrated strong production scalability and broad market acceptance. Since launching in October 2020, LakeShore Biopharma has distributed over 35.3 million doses to 1,911 county-level CDCs in China, representing 67.7% of coverage.

Clinical Pipeline

Progress of Phase III Clinical Trial on simplified four-dose regimen for YSJATM rabies vaccine

In October 2024, the NMPA approved LakeShore Biopharma to initiate a Phase III clinical trial evaluating a simplified four-dose regimen for YSJATM, including the Zagreb (2-1-1) and Modified Essen (1-1-1-1) regimens.

LakeShore Biopharma commenced this clinical trial in December 2024 and successfully completed the 90-day subject follow-up in July 2025. The Company expects to finish the interim analysis in the fourth quarter of 2025 and obtain the market approval in the fourth quarter of 2026.

The study aims to strengthen the competitiveness of the YSJATM rabies vaccine in the rapidly growing rabies vaccine market, demonstrate its clinical superiority, and garner broader recognition and support from hospitals, academic institutions, and industry stakeholders in China and globally.

Fiscal Year 2025Financial Results

Total Revenue

Total revenue rose by 7.2%, from RMB573.4 million in FY2024 to RMB615.0 million in FY2025. This growth was primarily driven by steady recovery of the domestic economy following the end of the COVID-19 emergency, with improved production and operations.

Gross Profit

Gross profit rose by 11.3%, from RMB455.7 million in FY2024 to RMB507.2 million in FY2025. This increase was primarily driven by higher sales volume. The gross profit margin also improved, from 79.5% in FY 2024 to 82.5% in FY 2025. The margin expansion was due to higher average unit prices and lower unit costs.

Selling and Marketing Expenses

Selling and marketing ("S&M") expenses decreased by 6.6%, from RMB301.3 million in FY2024 to RMB281.4 million in FY2025. This decline was mainly attributed to higher S&M spending in FY2024, driven by increased market promotion to strengthen market position and brand recognition, and to address intensified competition following additional approvals for human rabies vaccines in China.

General and Administrative Expenses

General and administrative expenses decreased by 7.9%, from RMB140.1 million in FY2024 to RMB129.0 million in FY2025. This reduction was primarily due to ongoing improvements in our cost control framework, achieved through systematic implementation of cost-saving and efficiency initiatives. These include optimization of management processes, tightening control over non-core spending, and improving resource utilization.

Research and Development Expenses

Research and development ("R&D")expenses in FY 2025 were RMB146.4 million, down from RMB302.8 million in FY2024, mainly due to: 1) the termination of COVID-19 vaccine commercialization, which led to reduced related testing and clinical costs; and 2) lower R&D spending on the PIKA rabies vaccine as the trial progressed to a later stage, follow-ups completed and focus shifted to lower cost data analysis.

Impairment Loss on Inventory, Property, Plant and Equipment, and Other Assets

Impairment loss on inventory, property, plant and equipment, and other assets decreased by 76.7%, from RMB157.4 million in FY2024 to RMB36.7 million in FY2025. This decrease was mainly attributed to the smaller reduction in PP&E impairment of equipment related to COVID-19 vaccines recognized in the current Fiscal Year compared to FY2024.

EBITDA and Adjusted EBITDA

EBITDA[1] and Adjusted EBITDA[2] were RMB(48.5 million) and RMB0.6 million, compared to RMB(368.7 million) and RMB(236.4 million) respectively, in FY2024.

Loss from Operations

Operating loss was RMB86.3 million, significantly lower than an operating loss of RMB445.8 million in FY2024.

Net Loss and Adjusted Net Loss

Net loss was RMB100.0 million, and adjusted net loss[3] was RMB40.0 million, in contrast to net loss of RMB433.5 million and adjusted net loss[3] of RMB266.3 million, respectively, in FY2024.

Balance Sheet

As of March 31, 2025, the Company had cash and cash equivalents of RMB107.5 million, compared to RMB246.6 million as of March 31, 2024. Our short-term loan and borrowings reached RMB390.4 million, compared to RMB318.5 million as of March 31, 2024.

Business Outlook

The Company anticipates total revenue in FY2026 to be between approximately RMB550 million and RMB650 million.

The above outlook is based on the information available as of the date of this press release and reflects the Company's current and preliminary expectations regarding its business situation and market conditions. The outlook is subject to changes, especially given uncertainties and situations related to market competitive dynamics, regulatory policies and other factors beyond its control.

[1]EBITDA is a non-GAAP financial measure, which is defined as net income (loss) before income tax benefit (expense), financial expenses and depreciation and amortization. See "Use of Non-GAAP Financial Measures" below

[2]Adjusted EBITDA is a non-GAAP financial measure, which is defined as net income(loss) before income tax benefit (expense), financial expenses, and depreciation and amortization ("EBITDA") adjusted to exclude share-based compensation expenses, impairment loss on inventory, property, plant and equipment and other assets, late fees related to social security insurance, other income (expense), fair value changes of warrant liability, and government grants. See "Use of Non-GAAP Financial Measures" below

[3]Adjusted net income (loss) is a non-GAAP financial measure, which is defined as net income (loss) excluding share-based compensation expenses, impairment loss on inventory, property, plant and equipment and other assets, and loss on disposal of property, plant and equipment. See "Use of Non-GAAP Financial Measures" below.

About LakeShore Biopharma

LakeShore Biopharma, previously known as YS Biopharma, is a global biopharmaceutical company dedicated to discovering, developing, manufacturing, and delivering new generations of vaccines and therapeutic biologics for infectious diseases and cancer. It has developed a proprietary PIKA®immunomodulating technology platform and a new generation of preventive and therapeutic biologics targeting Rabies, Hepatitis B, Influenza, and other virus infections. The Company operates in China, Singapore, and the Philippines, and is led by a management team that combines rich local expertise and global experience in the biopharmaceutical industry. For more information, please visit

Use of Non-GAAP Financial Measures

In evaluating the business, the Company considers and uses certain non-GAAP measures, including Adjusted EBITDA and adjusted net income (loss), as supplemental measures to review and assess its operating performance. The presentation of the non-GAAP financial measure is not intended to be considered in isolation or as a substitute for the financial information prepared and presented in accordance with U.S. GAAP. The Company defines Adjusted EBITDA as net income (loss) before income tax benefit (expense), financial expenses, and depreciation and amortization ("EBITDA") adjusted to exclude share-based compensation expenses, impairment loss on inventory, property, plant and equipment and other assets, late fees related to social security insurance, other income (expense), fair value changes of warrant liability, and government grants. The Company defines adjusted net income (loss) as net income (loss) excluding share-based compensation expenses, impairment loss on inventory, property, plant and equipment and other assets, and loss on disposal of property, plant and equipment. The Company presents the non-GAAP financial measures because they are used by the management to evaluate the operating performance and formulate business plans. The Company also believes that the use of the non-GAAP measures facilitates investors' assessment of its operating performance as this measure excludes certain finance or non-cash items that the Company does not believe directly reflect its core operations. The Company believes that excluding these items enables us to evaluate our performance period-over-period more effectively and relative to our competitors.

The non-GAAP financial measures are not defined under U.S. GAAP and are not presented in accordance with U.S. GAAP. The non-GAAP financial measures have limitations as analytical tools. One of the key limitations of using Adjusted EBITDA is that it does not reflect all items of income and expenses that affect the Company's operations. Share-based compensation, impairment loss on inventory, property, plant and equipment and other assets, Loss on disposal of Property, plant and equipment have been and may continue to be incurred in the business. Further, the non-GAAP measures may differ from the non-GAAP information used by other companies, including peer companies, and therefore their comparability may be limited.

The Company compensates for these limitations by reconciling the non-GAAP financial measure to the nearest U.S. GAAP performance measure, all of which should be considered when evaluating the Company's performance. The Company encourages you to review its financial information in its entirety and not rely on a single financial measure.

Reconciliations of LakeShore Biopharma's non-GAAP financial measures to the most comparable U.S. GAAP measure are included at the end of this press release.

Exchange Rate Information

This announcement contains translations of certain RMB amounts into U.S. dollars at a specified rate solely for the convenience of the reader. Unless otherwise noted, all translations from RMB to U.S. dollars are made at a rate of RMB7.1782 to US$1.00, the exchange rate set forth in the central parity rate release of the People's Bank of China on March 31, 2025.

Cautionary Statement Regarding Forward-Looking Statements

This press release contains "forward-looking statements" within the meaning of Section 27A of the Securities Act of 1933, as amended, Section 21E of the Securities Exchange Act of 1934, as amended, and the Private Securities Litigation Reform Act of 1995. All statements other than statements of historical or current fact included in this press release are forward-looking statements, including but not limited to statements regarding the expected growth and business outlook of LakeShore Biopharma, the development progress of all product candidates, the progress and results of all clinical trials, LakeShore Biopharma's ability to source and retain talent, and the cash position of LakeShore Biopharma. Forward-looking statements may be identified by the use of words such as "estimate," "plan," "project," "potential," "forecast," "intend," "will," "expect," "anticipate," "believe," "goal," "seek," "target" or other similar expressions that predict or indicate future events or trends or that are not statements of historical matters. These statements are based on various assumptions, whether identified in this press release, and on the current expectations of LakeShore Biopharma's management and are not predictions of actual performance.

LakeShore Biopharma cannot assure you the forward-looking statements in this press release will be accurate. These forward-looking statements are subject to a number of risks and uncertainties, including those included under the heading "Risk Factors" in the company's Annual Report on Form 20-F filed with the Securities and Exchange Commission, or SEC, and other risks described in documents subsequently filed by the company from time to time with the SEC. There may be additional risks that LakeShore Biopharma does not presently know or that LakeShore Biopharma currently believes are immaterial that could also cause actual results to differ from those contained in the forward-looking statements. In light of the significant uncertainties in these forward-looking statements, nothing in this press release should be regarded as a representation by any person that the forward-looking statements set forth herein will be achieved or that any of the contemplated results of such forward-looking statements will be achieved. The forward-looking statements in this press release represent the views of LakeShore Biopharma as of the date of this press release. Subsequent events and developments may cause those views to change. However, while LakeShore Biopharma may update these forward-looking statements in the future, there is no current intention to do so, except to the extent required by applicable law. You should, therefore, not rely on these forward-looking statements as representing the views of LakeShore Biopharma as of any date subsequent to the date of this press release. Except as may be required by law, LakeShore Biopharma does not undertake any duty to update these forward-looking statements.

LAKESHORE BIOPHARMA CO., LTD AND SUBSIDIARIES

CONSOLIDATED BALANCE SHEET (AUDITED)




As of March 31,




2024



2025



2025




(RMB)



(RMB)



(US$)


ASSETS










Current assets










Cash



246,351,231




28,083,556



$

3,912,340


Restricted cash



200,000




79,401,410




11,061,465


Accounts receivable



444,161,291




500,916,815




69,783,067


Advance to suppliers



1,662,739




1,687,964




235,151


Inventories



203,422,602




227,591,892




31,705,984


Prepaid expenses and other current assets



7,370,089




4,536,363




631,964


Total current assets



903,167,952




842,218,000




117,329,971


Non-current assets













Property, plant and equipment



473,348,006




413,501,445




57,605,172


Operating lease right-of-use assets



7,275,367




847,331




118,042


Deferred tax assets



23,634,189




27,946,500




3,893,247


Intangible assets



71,245,336




72,854,656




10,149,432


Other non-current assets



34,356,506




10,295,279




1,434,242


Total non-current assets



609,859,404




525,445,211




73,200,135


Total assets



1,513,027,356




1,367,663,211



$

190,530,106















LIABILITIES AND SHAREHOLDERS'
(DEFICIT)/EQUITY













Current liabilities













Bank loans and other borrowings



318,540,732




390,440,095



$

54,392,479


Accounts payable



67,774,798




49,551,779




6,903,093


Accrued expenses and other liabilities



408,737,969




382,847,958




53,334,812


Operating lease liabilities



5,156,540




457,012




63,667


Deferred government grants



2,015,693




1,455,678




202,792


Total current liabilities



802,225,732




824,752,522




114,896,843















Non-current liabilities













Bank loans and other borrowings



98,983,780




23,503,471




3,274,285


Operating lease liabilities



1,783,593




-




-


Deferred government grants



20,279,945




16,207,745




2,257,912


Warrants liability



4,548,004




3,444,842




479,903


Total non-current liabilities



125,595,322




43,156,058




6,012,100


Total liabilities



927,821,054




867,908,580




120,908,943















Shareholders'(deficit)/equity













Ordinary shares, par value US$0.0002 per share; 250,000,000
shares authorized; 19,022,795 and 20,766,531 shares issued
and outstanding as of March 31, 2024 and 2025, respectively *



26,105




28,603




3,985


Additional paid-in capital



2,950,862,914




2,964,482,986




412,984,172


Accumulated deficit



(2,307,502,836)




(2,407,485,287)




(335,388,438)


Accumulated other comprehensive loss



(58,179,881)




(57,271,671)




(7,978,556)


Total shareholders' equity



585,206,302




499,754,631




69,621,163


Total liabilities and shareholders' equity



1,513,027,356




1,367,663,211



$

190,530,106


*

Gives retroactive effect to the Share Consolidation in October 2024.

LAKESHORE BIOPHARMA CO., LTD AND SUBSIDIARIES

CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS (AUDITED)




Years Ended March 31,




2023



2024



2025



2025




(RMB)



(RMB)



(RMB)



(US$)


Revenues



687,201,070




573,418,256




614,961,584



$

85,670,723


Cost of revenues



153,360,262




117,688,301




107,772,147




15,013,812


Gross profit



533,840,808




455,729,955




507,189,437




70,656,911



















Operating expenses:

















Selling and marketing



272,927,356




301,259,528




281,429,426




39,206,128


General and administrative



72,939,790




140,086,062




128,967,761




17,966,588


Impairment loss on inventory, property, plant and
equipment and other assets



8,655,487




157,415,875




36,715,041




5,114,798


Research and development



318,700,526




302,800,992




146,369,093




20,390,779


Total operating expenses



673,223,159




901,562,457




593,481,321




82,678,293



















Loss from operations



(139,382,351)




(445,832,502)




(86,291,884)




(12,021,382)



















Other income (expenses):

















Late fees for taxes other than income tax



(3,603)




-




-




-


Late fees for social security insurance



(747,609)




(756,201)




(454,863)




(63,367)


Government grants



26,072,517




20,708,778




5,125,566




714,046


Financial expenses



(30,857,673)




(44,344,808)




(15,739,410)




(2,192,668)


Fair value changes of warrant liability



21,358




4,458,844




1,149,792




160,178


Other income(expense)



551,760




10,572,411




(4,718,525)




(657,341)


Total other income (expense)



(4,963,250)




(9,360,976)




(14,637,440)




(2,039,152)



















Loss before income taxes



(144,345,601)




(455,193,478)




(100,929,324)




(14,060,534)



















Income tax benefit(expense)



(1,133,504)




21,728,607




946,873




131,910



















Net loss



(145,479,105)




(433,464,871)




(99,982,451)




(13,928,624)


Accretion to redemption value of convertible
redeemable preferred shares



(137,991,697)




-




-




-


Net loss attributable to LakeShore Group



(283,470,802)




(433,464,871)




(99,982,451)



$

(13,928,624)



















Net loss



(145,479,105)




(433,464,871)




(99,982,451)



$

(13,928,624)


Other comprehensive income (loss), net of tax:
Foreign currency translation adjustment



(137,500,063)




(3,767,798)




908,210




126,523


Total comprehensive loss



(282,979,168)




(437,232,669)




(99,074,241)



$

(13,802,101)



















Loss per share*:

















� Basic and Diluted



(23.55)




(40.54)




(5.22)



$

(0.73)


Weighted average number of ordinary shares
outstanding*:

















� Basic and Diluted



6,178,547




10,692,312




19,158,907




19,158,907


*

Gives retroactive effect to the Share Consolidation in October 2024.

Lakeshore Biopharma Co., Ltd

Unaudited Reconciliations of GAAP And Non-GAAP Results


Years Ended March 31,



2024


2025


2025



RMB


RMB


US$








Net income (loss)


(433,464,871)


(99,982,451)

$

(13,928,624)

Add: income tax benefit (expense)


(21,728,607)


(946,873)


(131,910)

Add: financial expenses


44,344,808


15,739,410


2,192,668

Add: depreciation and amortization


42,185,383


36,651,608


5,105,961

EBITDA


(368,663,287)


(48,538,306)


(6,761,905)

Add: share-based compensation expenses


9,789,686


13,557,214


1,888,665

Add: impairment loss on inventory, property,
plant and equipment and other assets


157,415,875


36,715,041


5,114,798

late fees related to social security insurance


756,201


454,863


63,367

Add: other income (expense)


(10,572,411)


4,718,525


657,341

Add: fair value changes of warrant liability


(4,458,844)


(1,149,792)


(160,178)

Add: government grants


(20,708,778)


(5,125,566)


(714,046)

Adjusted EBITDA


(236,441,558)


631,979

$

88,041









Years Ended March 31,



2024


2025


2025



RMB


RMB


US$








Net income (loss)


(433,464,871)


(99,982,451)

$

(13,928,624)

Add: share-based compensation expenses


9,789,686


13,557,214


1,888,665

Add: impairment loss on inventory, property,
plant and equipment and other assets


157,415,875


36,715,041


5,114,798

Add: loss on disposal of property, plant and
equipment


13,135


9,777,030


1,362,045

Adjusted net income (loss)


(266,259,310)


(39,933,166)

$

(5,563,117)

Cision View original content:

SOURCE LakeShore Biopharma Co., Ltd.

FAQ

What were LakeShore Biopharma's (LSB) key financial results for FY2025?

LSB reported revenue of RMB615.0 million (7.2% YoY growth), gross profit of RMB507.2 million (11.3% YoY growth), and narrowed net loss to RMB100.0 million from RMB433.5 million in FY2024.

How many doses of YSJATM rabies vaccine has LakeShore Biopharma distributed in China?

Since October 2020, LSB has distributed over 35.3 million doses to 1,911 county-level CDCs in China, achieving 67.7% coverage.

What is LSB's revenue guidance for Fiscal Year 2026?

LakeShore Biopharma projects FY2026 revenue to be between RMB550 million and RMB650 million.

When does LakeShore Biopharma expect to receive market approval for its simplified four-dose YSJATM regimen?

LSB expects to complete interim analysis in Q4 2025 and aims to obtain market approval by the fourth quarter of 2026.

What are the main challenges facing LakeShore Biopharma in 2025?

LSB faces intensified competition in the rabies vaccine market, pricing pressures, limited distribution channel capacity, and cash constraints due to litigation with former Chairman affecting credit access.
LakeShore Biopharma Co., Ltd

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