[SCHEDULE 13G/A] Aprea Therapeutics, Inc. Common stock SEC Filing
Sio Capital Management, LLC reports beneficial ownership of 279,369 shares of Aprea Therapeutics common stock, representing 5.05% of the class as of June 30, 2025. The position is held for affiliated funds for which Sio is the registered investment adviser; Sio reports 0 sole voting or dispositive power and 279,369 shared voting and dispositive power.
The 5.05% figure is calculated using 5,525,172 shares outstanding as of April 22, 2025. The filing notes that the general partner and Michael Castor may be deemed to have influence over the accounts that own the shares, while expressly disclaiming beneficial ownership; the filer certifies the shares are held in the ordinary course of business and not to change or influence control.
Sio Capital Management, LLC comunica una partecipazione beneficiaria di 279,369 azioni ordinarie di Aprea Therapeutics, corrispondenti al 5,05% della classe al 30 giugno 2025. La posizione 猫 detenuta per fondi affiliati per i quali Sio 猫 il consulente d'investimento registrato; Sio dichiara di avere 0 poteri di voto o dispositivi esclusivi e 279,369 poteri di voto e dispositivi condivisi.
La percentuale del 5,05% 猫 calcolata usando 5,525,172 azioni in circolazione al 22 aprile 2025. Il deposito segnala che il general partner e Michael Castor possono essere ritenuti influenti sugli account che possiedono le azioni, pur rinunciando espressamente alla titolarit脿 beneficiaria; il dichiarante certifica che le azioni sono detenute nell'ordinaria gestione dell'attivit脿 e non per modificare o influenzare il controllo.
Sio Capital Management, LLC informa la propiedad beneficiaria de 279,369 acciones ordinarias de Aprea Therapeutics, que representan el 5,05% de la categor铆a a fecha del 30 de junio de 2025. La posici贸n est谩 mantenida para fondos afiliados de los que Sio es el asesor de inversi贸n registrado; Sio declara tener 0 poder de voto o disposici贸n en exclusiva y 279,369 poder de voto y disposici贸n compartida.
La cifra del 5,05% se calcula usando 5,525,172 acciones en circulaci贸n al 22 de abril de 2025. La presentaci贸n indica que el socio general y Michael Castor podr铆an considerarse con influencia sobre las cuentas que poseen las acciones, si bien renuncian expresamente a la propiedad beneficiaria; el declarante certifica que las acciones se mantienen en el curso ordinario del negocio y no para cambiar o influir en el control.
Sio Capital Management, LLC電� Aprea Therapeutics 氤错喌欤� 279,369欤茧ゼ 鞁れ鞝� 靻岇湢搿� 氤搓碃頃橂┌, 鞚措姅 2025雲� 6鞗� 30鞚� 旮办 頃措嫻 韥措灅鞀れ潣 5.05%鞐� 頃措嫻頃╇媹雼�. 頃措嫻 韽靺橃潃 Sio臧� 霌彪 韴瀽鞛愲靷 鞛堧姅 瓿勳棿 韼�霌滊摛鞚� 鞙勴暣 氤挫湢頃橁碃 鞛堨溂氅�, Sio電� 雼弲 鞚橁舶甓� 霕愲姅 觳橂秳甓岇潉 0鞙茧 氤搓碃頃橁碃 瓿惦彊 鞚橁舶甓� 氚� 觳橂秳甓岇潃 279,369搿� 氤搓碃頃╇媹雼�.
5.05% 靾橃箻電� 2025雲� 4鞗� 22鞚� 旮办 鞙犿喌欤检嫕靾� 5,525,172欤茧ゼ 靷毄頃� 瓿勳偘霅橃棃鞀惦媹雼�. 鞝滌稖靹滊鞐愲姅 鞚茧皹 韺岉姼雱堨檧 Michael Castor臧� 欤检嫕鞚� 氤挫湢頃� 瓿勳爼鞐� 雽�頃� 鞓來枼霠レ潉 頄夓偓頃� 靾� 鞛堧嫟瓿� 氤� 靾� 鞛堨溂雮� 鞁れ鞝� 靻岇湢毳� 氇呾嫓鞝侅溂搿� 攵�鞚疙暅雼り碃 旮办灛霅橃柎 鞛堨溂氅�, 鞝滌稖鞚胳潃 欤检嫕鞚� 鞓侅梾靸侅潣 韱奠儊鞝侅澑 瓯半灅 瓿检爼鞐愳劀 氤挫湢霅� 瓴冹澊氅� 歆�氚瓣秾鞚� 氤�瓴巾晿瓯半倶 頄夓偓頃橂牑電� 氇╈爜鞚� 鞎勲嫎鞚� 鞚胳頃╇媹雼�.
Sio Capital Management, LLC d茅clare 锚tre b茅n茅ficiaire de 279,369 actions ordinaires d'Aprea Therapeutics, repr茅sentant 5,05% de la cat茅gorie au 30 juin 2025. La position est d茅tenue pour des fonds affili茅s pour lesquels Sio est le conseiller en investissement enregistr茅 ; Sio indique disposer de 0 pouvoir de vote ou de disposition exclusif et de 279,369 pouvoirs de vote et de disposition partag茅s.
Le pourcentage de 5,05% est calcul茅 en utilisant 5,525,172 actions en circulation au 22 avril 2025. Le d茅p么t pr茅cise que le commandit茅 et Michael Castor peuvent 锚tre consid茅r茅s comme ayant une influence sur les comptes d茅tenant les actions, tout en d茅clinant express茅ment la qualit茅 de b茅n茅ficiaire ; le d茅clarant certifie que les actions sont d茅tenues dans le cours normal des affaires et non dans le but de modifier ou d'influencer le contr么le.
Sio Capital Management, LLC meldet eine wirtschaftliche Eigent眉merschaft von 279,369 Aktien der Stammaktien von Aprea Therapeutics, was 5,05% der Klasse zum 30. Juni 2025 entspricht. Die Position wird f眉r verbundene Fonds gehalten, f眉r die Sio als registrierter Anlageberater fungiert; Sio gibt 0 alleiniges Stimm- oder Verf眉gungsrecht und 279,369 gemeinsames Stimm- und Verf眉gungsrecht an.
Die Zahl von 5,05% wurde unter Verwendung von 5,525,172 ausstehenden Aktien zum 22. April 2025 berechnet. Die Meldung weist darauf hin, dass der Generalpartner und Michael Castor als einflussreich auf die Konten, die die Aktien halten, angesehen werden k枚nnten, w盲hrend sie ausdr眉cklich eine wirtschaftliche Eigent眉merschaft verneinen; der Meldende best盲tigt, dass die Aktien im normalen Gesch盲ftsablauf gehalten werden und nicht dazu dienen, die Kontrolle zu 盲ndern oder zu beeinflussen.
- Beneficial ownership disclosed: Sio reports ownership of 279,369 shares, equal to 5.05% of the class.
- Registered investment adviser status: Sio holds the shares for affiliated funds, clarifying the capacity in which the position is held.
- Transparency on intent: The filer certifies the securities are held in the ordinary course of business and not to influence control.
- No sole voting or dispositive power: Sio reports 0 sole voting and dispositive power, indicating no direct control over the shares.
- Attribution caveat: The filing notes the GP and Michael Castor may be deemed to have influence, which creates ambiguity about ultimate beneficial ownership despite the disclaimer.
Insights
TL;DR: Sio holds a disclosed 5.05% stake (279,369 shares) via advisory clients; material to the ownership register but does not indicate sole control.
Sio's reported 279,369 shares represent a meaningful, though non-controlling, stake in Aprea given the >5% disclosure threshold. The entire position is recorded as shared voting and dispositive power, with no sole powers, which implies influence through managed accounts rather than direct control. The percentage uses the issuer's reported outstanding share count of 5,525,172 as of April 22, 2025, providing a clear basis for the calculation. This filing updates public ownership information but contains no indication of an activist intent or change-of-control transaction.
TL;DR: Disclosure shows adviser-held shares with attribution language for the GP and Michael Castor, creating some ownership attribution ambiguity.
The filing clarifies that Sio acts as an investment adviser to funds that are the record owners and reports shared voting and dispositive power over the 279,369 shares. The statement that the GP and Michael Castor "may be deemed" to control voting or dispositive decisions introduces attribution caveats typical in adviser/GP structures and is expressly disclaimed. From a governance perspective, the disclosure is material for shareholder registry and proxy considerations but does not, by itself, signal a governance change or control contest.
Sio Capital Management, LLC comunica una partecipazione beneficiaria di 279,369 azioni ordinarie di Aprea Therapeutics, corrispondenti al 5,05% della classe al 30 giugno 2025. La posizione 猫 detenuta per fondi affiliati per i quali Sio 猫 il consulente d'investimento registrato; Sio dichiara di avere 0 poteri di voto o dispositivi esclusivi e 279,369 poteri di voto e dispositivi condivisi.
La percentuale del 5,05% 猫 calcolata usando 5,525,172 azioni in circolazione al 22 aprile 2025. Il deposito segnala che il general partner e Michael Castor possono essere ritenuti influenti sugli account che possiedono le azioni, pur rinunciando espressamente alla titolarit脿 beneficiaria; il dichiarante certifica che le azioni sono detenute nell'ordinaria gestione dell'attivit脿 e non per modificare o influenzare il controllo.
Sio Capital Management, LLC informa la propiedad beneficiaria de 279,369 acciones ordinarias de Aprea Therapeutics, que representan el 5,05% de la categor铆a a fecha del 30 de junio de 2025. La posici贸n est谩 mantenida para fondos afiliados de los que Sio es el asesor de inversi贸n registrado; Sio declara tener 0 poder de voto o disposici贸n en exclusiva y 279,369 poder de voto y disposici贸n compartida.
La cifra del 5,05% se calcula usando 5,525,172 acciones en circulaci贸n al 22 de abril de 2025. La presentaci贸n indica que el socio general y Michael Castor podr铆an considerarse con influencia sobre las cuentas que poseen las acciones, si bien renuncian expresamente a la propiedad beneficiaria; el declarante certifica que las acciones se mantienen en el curso ordinario del negocio y no para cambiar o influir en el control.
Sio Capital Management, LLC電� Aprea Therapeutics 氤错喌欤� 279,369欤茧ゼ 鞁れ鞝� 靻岇湢搿� 氤搓碃頃橂┌, 鞚措姅 2025雲� 6鞗� 30鞚� 旮办 頃措嫻 韥措灅鞀れ潣 5.05%鞐� 頃措嫻頃╇媹雼�. 頃措嫻 韽靺橃潃 Sio臧� 霌彪 韴瀽鞛愲靷 鞛堧姅 瓿勳棿 韼�霌滊摛鞚� 鞙勴暣 氤挫湢頃橁碃 鞛堨溂氅�, Sio電� 雼弲 鞚橁舶甓� 霕愲姅 觳橂秳甓岇潉 0鞙茧 氤搓碃頃橁碃 瓿惦彊 鞚橁舶甓� 氚� 觳橂秳甓岇潃 279,369搿� 氤搓碃頃╇媹雼�.
5.05% 靾橃箻電� 2025雲� 4鞗� 22鞚� 旮办 鞙犿喌欤检嫕靾� 5,525,172欤茧ゼ 靷毄頃� 瓿勳偘霅橃棃鞀惦媹雼�. 鞝滌稖靹滊鞐愲姅 鞚茧皹 韺岉姼雱堨檧 Michael Castor臧� 欤检嫕鞚� 氤挫湢頃� 瓿勳爼鞐� 雽�頃� 鞓來枼霠レ潉 頄夓偓頃� 靾� 鞛堧嫟瓿� 氤� 靾� 鞛堨溂雮� 鞁れ鞝� 靻岇湢毳� 氇呾嫓鞝侅溂搿� 攵�鞚疙暅雼り碃 旮办灛霅橃柎 鞛堨溂氅�, 鞝滌稖鞚胳潃 欤检嫕鞚� 鞓侅梾靸侅潣 韱奠儊鞝侅澑 瓯半灅 瓿检爼鞐愳劀 氤挫湢霅� 瓴冹澊氅� 歆�氚瓣秾鞚� 氤�瓴巾晿瓯半倶 頄夓偓頃橂牑電� 氇╈爜鞚� 鞎勲嫎鞚� 鞚胳頃╇媹雼�.
Sio Capital Management, LLC d茅clare 锚tre b茅n茅ficiaire de 279,369 actions ordinaires d'Aprea Therapeutics, repr茅sentant 5,05% de la cat茅gorie au 30 juin 2025. La position est d茅tenue pour des fonds affili茅s pour lesquels Sio est le conseiller en investissement enregistr茅 ; Sio indique disposer de 0 pouvoir de vote ou de disposition exclusif et de 279,369 pouvoirs de vote et de disposition partag茅s.
Le pourcentage de 5,05% est calcul茅 en utilisant 5,525,172 actions en circulation au 22 avril 2025. Le d茅p么t pr茅cise que le commandit茅 et Michael Castor peuvent 锚tre consid茅r茅s comme ayant une influence sur les comptes d茅tenant les actions, tout en d茅clinant express茅ment la qualit茅 de b茅n茅ficiaire ; le d茅clarant certifie que les actions sont d茅tenues dans le cours normal des affaires et non dans le but de modifier ou d'influencer le contr么le.
Sio Capital Management, LLC meldet eine wirtschaftliche Eigent眉merschaft von 279,369 Aktien der Stammaktien von Aprea Therapeutics, was 5,05% der Klasse zum 30. Juni 2025 entspricht. Die Position wird f眉r verbundene Fonds gehalten, f眉r die Sio als registrierter Anlageberater fungiert; Sio gibt 0 alleiniges Stimm- oder Verf眉gungsrecht und 279,369 gemeinsames Stimm- und Verf眉gungsrecht an.
Die Zahl von 5,05% wurde unter Verwendung von 5,525,172 ausstehenden Aktien zum 22. April 2025 berechnet. Die Meldung weist darauf hin, dass der Generalpartner und Michael Castor als einflussreich auf die Konten, die die Aktien halten, angesehen werden k枚nnten, w盲hrend sie ausdr眉cklich eine wirtschaftliche Eigent眉merschaft verneinen; der Meldende best盲tigt, dass die Aktien im normalen Gesch盲ftsablauf gehalten werden und nicht dazu dienen, die Kontrolle zu 盲ndern oder zu beeinflussen.
FAQ
How many APRE shares does Sio Capital own?
What percent of APRE does Sio Capital's holding represent?
As of what date is the reported ownership measured?
On what shares-out figure is the 5.05% based?
Does Sio have sole voting power over the APRE shares?
Was the stake acquired to influence control of the company?
