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[424B3] Kazia Therapeutics Limited American Prospectus Filed Pursuant to Rule 424(b)(3)

Filing Impact
(Low)
Filing Sentiment
(Neutral)
Form Type
424B3
Rhea-AI Filing Summary

Ryde Group Ltd (NYSE American: RYDE) has filed a Form F-3 shelf registration to give itself maximum flexibility to raise capital over the next three years.

  • Primary shelf: up to US$100 million in Class A ordinary shares, debt securities, warrants, rights or units that may be sold directly, or through underwriters, dealers or agents.
  • Rule 415 eligibility: the company’s public float is only US$4.768 million (14.9 million non-affiliate shares at US$0.32 on 7 Jul 2025). Under Instruction I.B.5, Ryde cannot sell more than one-third of that float (≈US$1.6 million) in any 12-month period until its market value exceeds US$75 million.
  • Carry-over securities: (i) 5.3 million Class A shares issuable on exercise of warrants sold in the Sept 2024 follow-on offering; (ii) conversion of the prior Form F-1 registration (File No. 333-282076) into the new shelf.
  • Resale component: 8.03 million Class A shares held by Octava Fund Ltd may be offered for secondary sale. Ryde will receive no proceeds.

The filing refreshes capital-raising capacity after a series of corporate actions:

  • US$12 million IPO (Mar 2024) and US$4.5 million follow-on (Sept 2024).
  • Secondary listings on Frankfurt and Stuttgart (Jun 2024) and several new subsidiaries (BVI and Singapore) to support expansion.
  • 40 % stake in Atoll Discovery (Jun 2025) paid with 4.85 million Ryde shares.

Business snapshot. Ryde is a Cayman Islands holding company whose operating subsidiaries in Singapore run a “super mobility app� offering car-pooling, ride-hailing (RydeX, RydeXL, RydeLUXE, RydePET, RydeTAXI) and quick-commerce parcel delivery (RydeSEND). Key strengths cited include dual-segment platform, scalable technology and experienced management.

Key risks spelled out in the prospectus:

  • Early-stage growth and continuing losses; profitability hinges on reducing driver/consumer incentives.
  • Intense competition from Grab, Gojek, ComfortDelGro, Lalamove and others.
  • Regulatory overhang (Platform Workers Act 2024, driver classification, data privacy, AML, LTA licensing).
  • Micro-cap status (US$0.32 share price), potential NYSE American listing compliance challenges and dilution from warrants, resale shares and future offerings.
  • Technology, cybersecurity and brand-reputation risks inherent in ride-hailing and delivery models.

Use of proceeds will be detailed in future prospectus supplements, but typical purposes include working capital, technology investments and potential acquisitions. The company’s ability to tap the full US$100 million depends on a significant improvement in market capitalization or uplisting.

Overall, the F-3 positions Ryde to raise incremental capital quickly, continue warrant coverage and permit shareholder liquidity, while highlighting substantial competitive, operational and regulatory headwinds that investors must weigh.

Ryde Group Ltd (NYSE American: RYDE) ha depositato una registrazione shelf di tipo Form F-3 per garantirsi la massima flessibilità nel raccogliere capitale nei prossimi tre anni.

  • Shelf principale: fino a 100 milioni di dollari USA in azioni ordinarie di Classe A, titoli di debito, warrant, diritti o unità che possono essere venduti direttamente o tramite sottoscrittori, dealer o agenti.
  • Idoneità alla Regola 415: il flottante pubblico della società è solo di 4,768 milioni di dollari USA (14,9 milioni di azioni non affiliate a 0,32 USD al 7 luglio 2025). Secondo l'Istruzione I.B.5, Ryde non può vendere più di un terzo di questo flottante (circa 1,6 milioni di dollari) in un periodo di 12 mesi finché il valore di mercato non supera i 75 milioni di dollari.
  • Titoli da riportare: (i) 5,3 milioni di azioni di Classe A emettibili tramite esercizio di warrant venduti nell’offerta di follow-on di settembre 2024; (ii) conversione della precedente registrazione Form F-1 (File No. 333-282076) nel nuovo shelf.
  • Componente di rivendita: 8,03 milioni di azioni di Classe A detenute da Octava Fund Ltd possono essere offerte per vendita secondaria. Ryde non riceverà proventi da questa operazione.

La registrazione aggiorna la capacità di raccolta dopo una serie di azioni societarie:

  • IPO da 12 milioni di dollari (marzo 2024) e follow-on da 4,5 milioni di dollari (settembre 2024).
  • Quotazioni secondarie a Francoforte e Stoccarda (giugno 2024) e diverse nuove controllate (BVI e Singapore) per supportare l’espansione.
  • Partecipazione del 40% in Atoll Discovery (giugno 2025) pagata con 4,85 milioni di azioni Ryde.

Profilo aziendale. Ryde è una holding con sede nelle Isole Cayman le cui controllate operative a Singapore gestiscono un “super app di mobilità� che offre car-pooling, ride-hailing (RydeX, RydeXL, RydeLUXE, RydePET, RydeTAXI) e consegne rapide di pacchi (RydeSEND). I punti di forza citati includono una piattaforma a doppio segmento, tecnologia scalabile e management esperto.

Principali rischi evidenziati nel prospetto:

  • Crescita in fase iniziale e perdite continue; la redditività dipende dalla riduzione degli incentivi per autisti e consumatori.
  • Concorrenza intensa da parte di Grab, Gojek, ComfortDelGro, Lalamove e altri.
  • Incertezze normative (Platform Workers Act 2024, classificazione degli autisti, privacy dei dati, AML, licenze LTA).
  • Status micro-cap (0,32 USD per azione), potenziali sfide di conformità alla quotazione NYSE American e diluizione da warrant, azioni di rivendita e future offerte.
  • Rischi tecnologici, di cybersecurity e reputazionali inerenti ai modelli di ride-hailing e consegna.

Utilizzo dei proventi sarà dettagliato in supplementi prospettici futuri, ma gli scopi tipici includono capitale circolante, investimenti tecnologici e potenziali acquisizioni. La capacità di raccogliere l’intero importo di 100 milioni di dollari dipende da un significativo miglioramento della capitalizzazione di mercato o da un uplisting.

In sintesi, il Form F-3 consente a Ryde di raccogliere capitale aggiuntivo rapidamente, mantenere la copertura dei warrant e permettere liquidità agli azionisti, evidenziando al contempo importanti sfide competitive, operative e regolamentari che gli investitori devono considerare.

Ryde Group Ltd (NYSE American: RYDE) ha presentado una registración shelf Form F-3 para otorgarse máxima flexibilidad para recaudar capital durante los próximos tres años.

  • Shelf primario: hasta 100 millones de dólares estadounidenses en acciones ordinarias Clase A, valores de deuda, warrants, derechos o unidades que pueden venderse directamente o a través de suscriptores, distribuidores o agentes.
  • Elegibilidad bajo la Regla 415: el flotante público de la empresa es solo de 4.768 millones de dólares (14.9 millones de acciones no afiliadas a 0.32 USD al 7 de julio de 2025). Según la Instrucción I.B.5, Ryde no puede vender más de un tercio de ese flotante (�1.6 millones de dólares) en cualquier período de 12 meses hasta que su valor de mercado supere los 75 millones de dólares.
  • Valores trasladados: (i) 5.3 millones de acciones Clase A emitibles mediante el ejercicio de warrants vendidos en la oferta follow-on de septiembre 2024; (ii) conversión del registro previo Form F-1 (Archivo No. 333-282076) al nuevo shelf.
  • Componente de reventa: 8.03 millones de acciones Clase A en posesión de Octava Fund Ltd pueden ofrecerse para venta secundaria. Ryde no recibirá ingresos por esta operación.

La presentación actualiza la capacidad de recaudación tras una serie de acciones corporativas:

  • IPO de 12 millones de dólares (marzo 2024) y follow-on de 4.5 millones de dólares (septiembre 2024).
  • Listados secundarios en Frankfurt y Stuttgart (junio 2024) y varias nuevas subsidiarias (BVI y Singapur) para apoyar la expansión.
  • Participación del 40% en Atoll Discovery (junio 2025) pagada con 4.85 millones de acciones Ryde.

Resumen del negocio. Ryde es una compañía holding de las Islas Caimán cuyas subsidiarias operativas en Singapur gestionan una “super app de movilidad� que ofrece carpooling, ride-hailing (RydeX, RydeXL, RydeLUXE, RydePET, RydeTAXI) y entrega rápida de paquetes (RydeSEND). Las fortalezas clave incluyen plataforma de doble segmento, tecnología escalable y gestión experimentada.

Riesgos clave destacados en el prospecto:

  • Crecimiento en etapa temprana y pérdidas continuas; la rentabilidad depende de reducir incentivos para conductores y consumidores.
  • Competencia intensa de Grab, Gojek, ComfortDelGro, Lalamove y otros.
  • Incógnitas regulatorias (Ley de Trabajadores de Plataforma 2024, clasificación de conductores, privacidad de datos, AML, licencias LTA).
  • Estado micro-cap (0.32 USD por acción), posibles desafíos de cumplimiento en NYSE American y dilución por warrants, acciones en reventa y futuras ofertas.
  • Riesgos tecnológicos, de ciberseguridad y reputación inherentes a los modelos de ride-hailing y entrega.

Uso de los fondos se detallará en suplementos futuros del prospecto, pero los propósitos típicos incluyen capital de trabajo, inversiones tecnológicas y adquisiciones potenciales. La capacidad de utilizar la totalidad de los 100 millones de dólares depende de una mejora significativa en la capitalización de mercado o un uplisting.

En conjunto, el Form F-3 posiciona a Ryde para recaudar capital incremental rápidamente, mantener la cobertura de warrants y permitir liquidez a los accionistas, mientras resalta importantes desafíos competitivos, operativos y regulatorios que los inversores deben considerar.

Ryde Group Ltd (NYSE American: RYDE)� 향후 3년간 자본 조달� 최대 유연성을 확보하기 위해 Form F-3 선반 등록� 제출했습니다.

  • 주요 선반: 클래� A 보통�, 채무 증권, 워런�, 권리 또는 단위� 최대 1� 달러까지 직접 판매하거� 인수�, 딜러 또는 대리인� 통해 판매� � 있습니다.
  • 규칙 415 적격�: 회사� 공개 유통 주식 가치는 단지 476.8� 달러(2025� 7� 7� 기준 비계� 주식 1,490� �, 주당 0.32달러)입니�. 지� I.B.5� 따라 Ryde� 시장 가치가 7,500� 달러� 초과� 때까지 12개월 동안 � 유통 주식� 3분의 1(� 160� 달러) 이상� 판매� � 없습니다.
  • 이월 증권: (i) 2024� 9� 후속 공모에서 판매� 워런� 행사� 발행 가능한 530� 클래� A 주식; (ii) 이전 Form F-1 등록(File No. 333-282076)� 새로� 선반으로� 전환.
  • 재판� 구성 요소: Octava Fund Ltd가 보유� 803� 클래� A 주식� 2� 판매용으� 제공� � 있으�, Ryde� 수익� 받지 않습니다.

이번 제출은 일련� 기업 활동 이후 자본 조달 능력� 갱신합니�:

  • 1,200� 달러 IPO(2024� 3�) � 450� 달러 후속 공모(2024� 9�).
  • 프랑크푸르트 � 슈투트가르트에서� 2� 상장(2024� 6�) � 확장� 지원하� 위한 여러 신규 자회�(BVI � 싱가포르).
  • Atoll Discovery 지� 40%(2025� 6�), 485� Ryde 주식으로 지�.

사업 개요. Ryde� 케이맨 제도� 본사� � 지주회사로 싱가포르� 있는 운영 자회사가 카풀, 라이드헤일링(RydeX, RydeXL, RydeLUXE, RydePET, RydeTAXI) � 빠른 배송(RydeSEND)� 제공하는 “슈� 모빌리티 앱”을 운영합니�. 주요 강점으로� 이중 세그먼트 플랫�, 확장 가능한 기술 � 경험 많은 경영진이 언급되었습니�.

투자설명서에 명시� 주요 위험:

  • 초기 성장 단계 � 지속적� 손실; 수익성은 운전� � 소비� 인센티브 축소� 달려 있음.
  • Grab, Gojek, ComfortDelGro, Lalamove 등과� 치열� 경쟁.
  • 규제 불확실성(2024� 플랫� 근로자법, 운전� 분류, 데이� 프라이버�, 자금세탁방지, LTA 라이선스).
  • 마이크로� 상태(주당 0.32달러), NYSE American 상장 규정 준� 문제 가능성 � 워런�, 재판� 주식, 미래 공모� 따른 희석 위험.
  • 라이드헤일링 � 배송 모델� 내재� 기술, 사이� 보안 � 브랜� 평판 위험.

자금 사용은 향후 증보� 설명서에� 자세� 다루겠지�, 일반적으� 운전자본, 기술 투자 � 잠재� 인수� 사용� 예정입니�. 1� 달러 전액 조달은 시가총액� 상당� 개선 또는 상위시장 이전� 달려 있습니다.

전반적으� Form F-3� Ryde가 추가 자본� 신속� 조달하고 워런� 커버리지� 유지하며 주주 유동성을 허용하는 동시� 투자자가 신중� 고려해야 � 상당� 경쟁, 운영 � 규제 위험� 부각합니다.

Ryde Group Ltd (NYSE American : RYDE) a déposé un enregistrement shelf Form F-3 afin de se donner une flexibilité maximale pour lever des capitaux au cours des trois prochaines années.

  • Shelf principal : ܲ'à 100 millions de dollars US en actions ordinaires de classe A, titres de dette, bons de souscription, droits ou unités pouvant être vendus directement ou par l'intermédiaire de souscripteurs, courtiers ou agents.
  • Éligibilité à la règle 415 : le flottant public de la société est seulement de 4,768 millions de dollars US (14,9 millions d’actions non affiliées à 0,32 USD au 7 juillet 2025). Selon l’Instruction I.B.5, Ryde ne peut pas vendre plus d’un tiers de ce flottant (�1,6 million de dollars) sur une période de 12 mois tant que sa capitalisation boursière ne dépasse pas 75 millions de dollars.
  • Titres reportés : (i) 5,3 millions d’actions de classe A pouvant être émises à l’exercice de bons de souscription vendus lors de l’offre de suivi de septembre 2024 ; (ii) conversion de l’enregistrement Form F-1 antérieur (dossier n° 333-282076) dans le nouveau shelf.
  • Composante de revente : 8,03 millions d’actions de classe A détenues par Octava Fund Ltd peuvent être proposées à la vente secondaire. Ryde ne recevra aucun produit de cette opération.

Le dépôt actualise la capacité de levée de fonds après une série d’actions corporatives :

  • IPO de 12 millions de dollars US (mars 2024) et offre de suivi de 4,5 millions de dollars US (septembre 2024).
  • Cotations secondaires à Francfort et Stuttgart (juin 2024) et plusieurs nouvelles filiales (BVI et Singapour) pour soutenir l’expansion.
  • Participation de 40 % dans Atoll Discovery (juin 2025) payée avec 4,85 millions d’actions Ryde.

Présentation de l’entreprise. Ryde est une société holding des îles Caïmans dont les filiales opérationnelles à Singapour gèrent une « super application de mobilité » offrant covoiturage, ride-hailing (RydeX, RydeXL, RydeLUXE, RydePET, RydeTAXI) et livraison rapide de colis (RydeSEND). Les points forts cités incluent une plateforme à double segment, une technologie évolutive et une direction expérimentée.

Principaux risques mentionnés dans le prospectus :

  • Croissance en phase initiale et pertes continues ; la rentabilité dépend de la réduction des incitations aux conducteurs et aux consommateurs.
  • Concurrence intense de la part de Grab, Gojek, ComfortDelGro, Lalamove et autres.
  • Incertitudes réglementaires (Platform Workers Act 2024, classification des conducteurs, confidentialité des données, AML, licences LTA).
  • Statut micro-cap (0,32 USD par action), défis potentiels de conformité à la cotation NYSE American et dilution due aux bons de souscription, actions revendues et futures émissions.
  • Risques technologiques, cybersécurité et réputation de marque inhérents aux modèles de ride-hailing et de livraison.

Utilisation des fonds sera détaillée dans de futurs suppléments au prospectus, mais les usages typiques incluent le fonds de roulement, les investissements technologiques et les acquisitions potentielles. La capacité de lever l’intégralité des 100 millions de dollars dépend d’une amélioration significative de la capitalisation boursière ou d’un passage à un marché supérieur.

Dans l’ensemble, le Form F-3 positionne Ryde pour lever rapidement des capitaux supplémentaires, maintenir la couverture des bons de souscription et permettre la liquidité des actionnaires, tout en soulignant des vents contraires importants sur le plan concurrentiel, opérationnel et réglementaire que les investisseurs doivent prendre en compte.

Ryde Group Ltd (NYSE American: RYDE) hat eine Form F-3 Shelf-Registrierung eingereicht, um sich maximale Flexibilität für die Kapitalaufnahme in den nächsten drei Jahren zu sichern.

  • Primärer Shelf: Bis zu 100 Millionen US-Dollar in Stammaktien der Klasse A, Schuldverschreibungen, Warrants, Bezugsrechten oder Einheiten, die direkt oder über Underwriter, Händler oder Agenten verkauft werden können.
  • Regel 415-Eignung: Der öffentliche Streubesitz des Unternehmens beträgt nur 4,768 Millionen US-Dollar (14,9 Millionen nicht verbundene Aktien zu 0,32 USD am 7. Juli 2025). Nach Instruktion I.B.5 darf Ryde nicht mehr als ein Drittel dieses Streubesitzes (�1,6 Millionen USD) innerhalb von 12 Monaten verkaufen, bis der Marktwert 75 Millionen USD übersteigt.
  • Übertragene Wertpapiere: (i) 5,3 Millionen Klasse-A-Aktien, die durch Ausübung von Warrants aus dem Folgeangebot im September 2024 ausgegeben werden können; (ii) Umwandlung der vorherigen Form F-1-Registrierung (Datei Nr. 333-282076) in den neuen Shelf.
  • Wiederverkaufskomponente: 8,03 Millionen Klasse-A-Aktien, die von Octava Fund Ltd gehalten werden, können zum Sekundärverkauf angeboten werden. Ryde erhält keine Erlöse daraus.

Die Einreichung erneuert die Kapitalaufnahmefähigkeit nach einer Reihe von Unternehmensmaßnahmen:

  • 12 Millionen USD IPO (März 2024) und 4,5 Millionen USD Folgeangebot (September 2024).
  • Sekundärnotierungen in Frankfurt und Stuttgart (Juni 2024) sowie mehrere neue Tochtergesellschaften (BVI und Singapur) zur Unterstützung der Expansion.
  • 40 % Beteiligung an Atoll Discovery (Juni 2025), bezahlt mit 4,85 Millionen Ryde-Aktien.

ұäڳٲü. Ryde ist eine Holdinggesellschaft auf den Cayman Islands, deren operative Tochtergesellschaften in Singapur eine „Super-Mobilitäts-App� betreiben, die Carpooling, Ride-Hailing (RydeX, RydeXL, RydeLUXE, RydePET, RydeTAXI) und schnelle Paketzustellung (RydeSEND) anbietet. Zu den wichtigsten Stärken zählen eine Dual-Segment-Plattform, skalierbare Technologie und erfahrenes Management.

Wesentliche Risiken im Prospekt:

  • Frühe Wachstumsphase und anhaltende Verluste; Profitabilität hängt von der Reduzierung von Anreizen für Fahrer und Verbraucher ab.
  • Intensiver Wettbewerb durch Grab, Gojek, ComfortDelGro, Lalamove und andere.
  • Regulatorische Unsicherheiten (Platform Workers Act 2024, Fahrerklassifizierung, Datenschutz, AML, LTA-Lizenzen).
  • Micro-Cap-Status (0,32 USD Aktienkurs), potenzielle NYSE American-Listing-Compliance-Herausforderungen und Verwässerung durch Warrants, Wiederverkaufsaktien und zukünftige Angebote.
  • Technologie-, Cybersecurity- und Markenreputationsrisiken, die in Ride-Hailing- und Zustellmodellen inhärent sind.

Verwendung der Erlöse wird in zukünftigen Prospektergänzungen detailliert, typische Zwecke sind jedoch Betriebskapital, Technologieinvestitionen und potenzielle Akquisitionen. Die Fähigkeit des Unternehmens, die vollen 100 Millionen USD zu nutzen, hängt von einer deutlichen Verbesserung der Marktkapitalisierung oder einem Uplisting ab.

Insgesamt positioniert das F-3 Ryde, um schnell zusätzliches Kapital zu beschaffen, die Warrant-Abdeckung fortzusetzen und Aktionärsliquidität zu ermöglichen, während erhebliche wettbewerbliche, operative und regulatorische Herausforderungen hervorgehoben werden, die Investoren abwägen müssen.

Positive
  • US$100 million shelf registration provides flexible, low-cost access to capital markets for future growth.
  • Combines prior F-1 warrants into the shelf, maintaining registration efficiency and avoiding duplicate fees.
  • Secondary listing in Germany expands investor base and potential liquidity.
  • Recent acquisitions and new subsidiaries demonstrate active expansion strategy beyond core ride-hailing.
Negative
  • Micro-cap status (US$4.768 million float) severely limits near-term primary issuance to ≈US$1.6 million.
  • Significant potential dilution: 5.3 million warrant shares plus 8.03 million resale shares atop any new issuance.
  • Competitive pressure from larger regional players (Grab, Gojek) may force continued incentive spend and delay profitability.
  • Regulatory uncertainties—new Platform Workers Act, data-privacy and LTA licensing—could raise costs or constrain the model.

Insights

TL;DR � Shelf unlocks flexible capital but dilution risk looms for tiny float.

The F-3 transforms Ryde’s capital stack by rolling warrants and a US$100 million shelf into one vehicle. Near-term primary issuance, however, is effectively capped at ~US$1.6 million under I.B.5 because the public float is just US$4.8 million. That means the filing is more about readiness than immediate cash. For a micro-cap in a cash-intensive ride-hailing model, the extra financing option is positive, but investors should expect incremental raises and dilution rather than a single large deal. Secondary resale of 8 million shares (�37 % of current Class A count) could add to selling pressure. Credit metrics are not disclosed here; absent earnings visibility, Ryde may rely on equity. Net impact: strategically useful, financially neutral until the market cap grows.

TL;DR � Extensive risk factors underscore execution, regulatory and listing vulnerabilities.

Ryde’s prospectus lists over 40 specific risks, many structural: regulatory flux (Platform Workers Act, gig-economy rules), possible driver re-classification, cyber breaches, and a sub-US$1 share price bordering on NYSE American deficiency. The company’s reliance on incentives to stimulate usage collides with its need to conserve cash. A US$100 million shelf signals ambition but could overwhelm the float, especially with 5.3 million warrant shares and 8.03 million resale shares pending. For a business operating in one city, concentration risk is high. Until Ryde demonstrates sustained revenue growth and lower cash burn, the filing is more defensive than catalytic.

Ryde Group Ltd (NYSE American: RYDE) ha depositato una registrazione shelf di tipo Form F-3 per garantirsi la massima flessibilità nel raccogliere capitale nei prossimi tre anni.

  • Shelf principale: fino a 100 milioni di dollari USA in azioni ordinarie di Classe A, titoli di debito, warrant, diritti o unità che possono essere venduti direttamente o tramite sottoscrittori, dealer o agenti.
  • Idoneità alla Regola 415: il flottante pubblico della società è solo di 4,768 milioni di dollari USA (14,9 milioni di azioni non affiliate a 0,32 USD al 7 luglio 2025). Secondo l'Istruzione I.B.5, Ryde non può vendere più di un terzo di questo flottante (circa 1,6 milioni di dollari) in un periodo di 12 mesi finché il valore di mercato non supera i 75 milioni di dollari.
  • Titoli da riportare: (i) 5,3 milioni di azioni di Classe A emettibili tramite esercizio di warrant venduti nell’offerta di follow-on di settembre 2024; (ii) conversione della precedente registrazione Form F-1 (File No. 333-282076) nel nuovo shelf.
  • Componente di rivendita: 8,03 milioni di azioni di Classe A detenute da Octava Fund Ltd possono essere offerte per vendita secondaria. Ryde non riceverà proventi da questa operazione.

La registrazione aggiorna la capacità di raccolta dopo una serie di azioni societarie:

  • IPO da 12 milioni di dollari (marzo 2024) e follow-on da 4,5 milioni di dollari (settembre 2024).
  • Quotazioni secondarie a Francoforte e Stoccarda (giugno 2024) e diverse nuove controllate (BVI e Singapore) per supportare l’espansione.
  • Partecipazione del 40% in Atoll Discovery (giugno 2025) pagata con 4,85 milioni di azioni Ryde.

Profilo aziendale. Ryde è una holding con sede nelle Isole Cayman le cui controllate operative a Singapore gestiscono un “super app di mobilità� che offre car-pooling, ride-hailing (RydeX, RydeXL, RydeLUXE, RydePET, RydeTAXI) e consegne rapide di pacchi (RydeSEND). I punti di forza citati includono una piattaforma a doppio segmento, tecnologia scalabile e management esperto.

Principali rischi evidenziati nel prospetto:

  • Crescita in fase iniziale e perdite continue; la redditività dipende dalla riduzione degli incentivi per autisti e consumatori.
  • Concorrenza intensa da parte di Grab, Gojek, ComfortDelGro, Lalamove e altri.
  • Incertezze normative (Platform Workers Act 2024, classificazione degli autisti, privacy dei dati, AML, licenze LTA).
  • Status micro-cap (0,32 USD per azione), potenziali sfide di conformità alla quotazione NYSE American e diluizione da warrant, azioni di rivendita e future offerte.
  • Rischi tecnologici, di cybersecurity e reputazionali inerenti ai modelli di ride-hailing e consegna.

Utilizzo dei proventi sarà dettagliato in supplementi prospettici futuri, ma gli scopi tipici includono capitale circolante, investimenti tecnologici e potenziali acquisizioni. La capacità di raccogliere l’intero importo di 100 milioni di dollari dipende da un significativo miglioramento della capitalizzazione di mercato o da un uplisting.

In sintesi, il Form F-3 consente a Ryde di raccogliere capitale aggiuntivo rapidamente, mantenere la copertura dei warrant e permettere liquidità agli azionisti, evidenziando al contempo importanti sfide competitive, operative e regolamentari che gli investitori devono considerare.

Ryde Group Ltd (NYSE American: RYDE) ha presentado una registración shelf Form F-3 para otorgarse máxima flexibilidad para recaudar capital durante los próximos tres años.

  • Shelf primario: hasta 100 millones de dólares estadounidenses en acciones ordinarias Clase A, valores de deuda, warrants, derechos o unidades que pueden venderse directamente o a través de suscriptores, distribuidores o agentes.
  • Elegibilidad bajo la Regla 415: el flotante público de la empresa es solo de 4.768 millones de dólares (14.9 millones de acciones no afiliadas a 0.32 USD al 7 de julio de 2025). Según la Instrucción I.B.5, Ryde no puede vender más de un tercio de ese flotante (�1.6 millones de dólares) en cualquier período de 12 meses hasta que su valor de mercado supere los 75 millones de dólares.
  • Valores trasladados: (i) 5.3 millones de acciones Clase A emitibles mediante el ejercicio de warrants vendidos en la oferta follow-on de septiembre 2024; (ii) conversión del registro previo Form F-1 (Archivo No. 333-282076) al nuevo shelf.
  • Componente de reventa: 8.03 millones de acciones Clase A en posesión de Octava Fund Ltd pueden ofrecerse para venta secundaria. Ryde no recibirá ingresos por esta operación.

La presentación actualiza la capacidad de recaudación tras una serie de acciones corporativas:

  • IPO de 12 millones de dólares (marzo 2024) y follow-on de 4.5 millones de dólares (septiembre 2024).
  • Listados secundarios en Frankfurt y Stuttgart (junio 2024) y varias nuevas subsidiarias (BVI y Singapur) para apoyar la expansión.
  • Participación del 40% en Atoll Discovery (junio 2025) pagada con 4.85 millones de acciones Ryde.

Resumen del negocio. Ryde es una compañía holding de las Islas Caimán cuyas subsidiarias operativas en Singapur gestionan una “super app de movilidad� que ofrece carpooling, ride-hailing (RydeX, RydeXL, RydeLUXE, RydePET, RydeTAXI) y entrega rápida de paquetes (RydeSEND). Las fortalezas clave incluyen plataforma de doble segmento, tecnología escalable y gestión experimentada.

Riesgos clave destacados en el prospecto:

  • Crecimiento en etapa temprana y pérdidas continuas; la rentabilidad depende de reducir incentivos para conductores y consumidores.
  • Competencia intensa de Grab, Gojek, ComfortDelGro, Lalamove y otros.
  • Incógnitas regulatorias (Ley de Trabajadores de Plataforma 2024, clasificación de conductores, privacidad de datos, AML, licencias LTA).
  • Estado micro-cap (0.32 USD por acción), posibles desafíos de cumplimiento en NYSE American y dilución por warrants, acciones en reventa y futuras ofertas.
  • Riesgos tecnológicos, de ciberseguridad y reputación inherentes a los modelos de ride-hailing y entrega.

Uso de los fondos se detallará en suplementos futuros del prospecto, pero los propósitos típicos incluyen capital de trabajo, inversiones tecnológicas y adquisiciones potenciales. La capacidad de utilizar la totalidad de los 100 millones de dólares depende de una mejora significativa en la capitalización de mercado o un uplisting.

En conjunto, el Form F-3 posiciona a Ryde para recaudar capital incremental rápidamente, mantener la cobertura de warrants y permitir liquidez a los accionistas, mientras resalta importantes desafíos competitivos, operativos y regulatorios que los inversores deben considerar.

Ryde Group Ltd (NYSE American: RYDE)� 향후 3년간 자본 조달� 최대 유연성을 확보하기 위해 Form F-3 선반 등록� 제출했습니다.

  • 주요 선반: 클래� A 보통�, 채무 증권, 워런�, 권리 또는 단위� 최대 1� 달러까지 직접 판매하거� 인수�, 딜러 또는 대리인� 통해 판매� � 있습니다.
  • 규칙 415 적격�: 회사� 공개 유통 주식 가치는 단지 476.8� 달러(2025� 7� 7� 기준 비계� 주식 1,490� �, 주당 0.32달러)입니�. 지� I.B.5� 따라 Ryde� 시장 가치가 7,500� 달러� 초과� 때까지 12개월 동안 � 유통 주식� 3분의 1(� 160� 달러) 이상� 판매� � 없습니다.
  • 이월 증권: (i) 2024� 9� 후속 공모에서 판매� 워런� 행사� 발행 가능한 530� 클래� A 주식; (ii) 이전 Form F-1 등록(File No. 333-282076)� 새로� 선반으로� 전환.
  • 재판� 구성 요소: Octava Fund Ltd가 보유� 803� 클래� A 주식� 2� 판매용으� 제공� � 있으�, Ryde� 수익� 받지 않습니다.

이번 제출은 일련� 기업 활동 이후 자본 조달 능력� 갱신합니�:

  • 1,200� 달러 IPO(2024� 3�) � 450� 달러 후속 공모(2024� 9�).
  • 프랑크푸르트 � 슈투트가르트에서� 2� 상장(2024� 6�) � 확장� 지원하� 위한 여러 신규 자회�(BVI � 싱가포르).
  • Atoll Discovery 지� 40%(2025� 6�), 485� Ryde 주식으로 지�.

사업 개요. Ryde� 케이맨 제도� 본사� � 지주회사로 싱가포르� 있는 운영 자회사가 카풀, 라이드헤일링(RydeX, RydeXL, RydeLUXE, RydePET, RydeTAXI) � 빠른 배송(RydeSEND)� 제공하는 “슈� 모빌리티 앱”을 운영합니�. 주요 강점으로� 이중 세그먼트 플랫�, 확장 가능한 기술 � 경험 많은 경영진이 언급되었습니�.

투자설명서에 명시� 주요 위험:

  • 초기 성장 단계 � 지속적� 손실; 수익성은 운전� � 소비� 인센티브 축소� 달려 있음.
  • Grab, Gojek, ComfortDelGro, Lalamove 등과� 치열� 경쟁.
  • 규제 불확실성(2024� 플랫� 근로자법, 운전� 분류, 데이� 프라이버�, 자금세탁방지, LTA 라이선스).
  • 마이크로� 상태(주당 0.32달러), NYSE American 상장 규정 준� 문제 가능성 � 워런�, 재판� 주식, 미래 공모� 따른 희석 위험.
  • 라이드헤일링 � 배송 모델� 내재� 기술, 사이� 보안 � 브랜� 평판 위험.

자금 사용은 향후 증보� 설명서에� 자세� 다루겠지�, 일반적으� 운전자본, 기술 투자 � 잠재� 인수� 사용� 예정입니�. 1� 달러 전액 조달은 시가총액� 상당� 개선 또는 상위시장 이전� 달려 있습니다.

전반적으� Form F-3� Ryde가 추가 자본� 신속� 조달하고 워런� 커버리지� 유지하며 주주 유동성을 허용하는 동시� 투자자가 신중� 고려해야 � 상당� 경쟁, 운영 � 규제 위험� 부각합니다.

Ryde Group Ltd (NYSE American : RYDE) a déposé un enregistrement shelf Form F-3 afin de se donner une flexibilité maximale pour lever des capitaux au cours des trois prochaines années.

  • Shelf principal : ܲ'à 100 millions de dollars US en actions ordinaires de classe A, titres de dette, bons de souscription, droits ou unités pouvant être vendus directement ou par l'intermédiaire de souscripteurs, courtiers ou agents.
  • Éligibilité à la règle 415 : le flottant public de la société est seulement de 4,768 millions de dollars US (14,9 millions d’actions non affiliées à 0,32 USD au 7 juillet 2025). Selon l’Instruction I.B.5, Ryde ne peut pas vendre plus d’un tiers de ce flottant (�1,6 million de dollars) sur une période de 12 mois tant que sa capitalisation boursière ne dépasse pas 75 millions de dollars.
  • Titres reportés : (i) 5,3 millions d’actions de classe A pouvant être émises à l’exercice de bons de souscription vendus lors de l’offre de suivi de septembre 2024 ; (ii) conversion de l’enregistrement Form F-1 antérieur (dossier n° 333-282076) dans le nouveau shelf.
  • Composante de revente : 8,03 millions d’actions de classe A détenues par Octava Fund Ltd peuvent être proposées à la vente secondaire. Ryde ne recevra aucun produit de cette opération.

Le dépôt actualise la capacité de levée de fonds après une série d’actions corporatives :

  • IPO de 12 millions de dollars US (mars 2024) et offre de suivi de 4,5 millions de dollars US (septembre 2024).
  • Cotations secondaires à Francfort et Stuttgart (juin 2024) et plusieurs nouvelles filiales (BVI et Singapour) pour soutenir l’expansion.
  • Participation de 40 % dans Atoll Discovery (juin 2025) payée avec 4,85 millions d’actions Ryde.

Présentation de l’entreprise. Ryde est une société holding des îles Caïmans dont les filiales opérationnelles à Singapour gèrent une « super application de mobilité » offrant covoiturage, ride-hailing (RydeX, RydeXL, RydeLUXE, RydePET, RydeTAXI) et livraison rapide de colis (RydeSEND). Les points forts cités incluent une plateforme à double segment, une technologie évolutive et une direction expérimentée.

Principaux risques mentionnés dans le prospectus :

  • Croissance en phase initiale et pertes continues ; la rentabilité dépend de la réduction des incitations aux conducteurs et aux consommateurs.
  • Concurrence intense de la part de Grab, Gojek, ComfortDelGro, Lalamove et autres.
  • Incertitudes réglementaires (Platform Workers Act 2024, classification des conducteurs, confidentialité des données, AML, licences LTA).
  • Statut micro-cap (0,32 USD par action), défis potentiels de conformité à la cotation NYSE American et dilution due aux bons de souscription, actions revendues et futures émissions.
  • Risques technologiques, cybersécurité et réputation de marque inhérents aux modèles de ride-hailing et de livraison.

Utilisation des fonds sera détaillée dans de futurs suppléments au prospectus, mais les usages typiques incluent le fonds de roulement, les investissements technologiques et les acquisitions potentielles. La capacité de lever l’intégralité des 100 millions de dollars dépend d’une amélioration significative de la capitalisation boursière ou d’un passage à un marché supérieur.

Dans l’ensemble, le Form F-3 positionne Ryde pour lever rapidement des capitaux supplémentaires, maintenir la couverture des bons de souscription et permettre la liquidité des actionnaires, tout en soulignant des vents contraires importants sur le plan concurrentiel, opérationnel et réglementaire que les investisseurs doivent prendre en compte.

Ryde Group Ltd (NYSE American: RYDE) hat eine Form F-3 Shelf-Registrierung eingereicht, um sich maximale Flexibilität für die Kapitalaufnahme in den nächsten drei Jahren zu sichern.

  • Primärer Shelf: Bis zu 100 Millionen US-Dollar in Stammaktien der Klasse A, Schuldverschreibungen, Warrants, Bezugsrechten oder Einheiten, die direkt oder über Underwriter, Händler oder Agenten verkauft werden können.
  • Regel 415-Eignung: Der öffentliche Streubesitz des Unternehmens beträgt nur 4,768 Millionen US-Dollar (14,9 Millionen nicht verbundene Aktien zu 0,32 USD am 7. Juli 2025). Nach Instruktion I.B.5 darf Ryde nicht mehr als ein Drittel dieses Streubesitzes (�1,6 Millionen USD) innerhalb von 12 Monaten verkaufen, bis der Marktwert 75 Millionen USD übersteigt.
  • Übertragene Wertpapiere: (i) 5,3 Millionen Klasse-A-Aktien, die durch Ausübung von Warrants aus dem Folgeangebot im September 2024 ausgegeben werden können; (ii) Umwandlung der vorherigen Form F-1-Registrierung (Datei Nr. 333-282076) in den neuen Shelf.
  • Wiederverkaufskomponente: 8,03 Millionen Klasse-A-Aktien, die von Octava Fund Ltd gehalten werden, können zum Sekundärverkauf angeboten werden. Ryde erhält keine Erlöse daraus.

Die Einreichung erneuert die Kapitalaufnahmefähigkeit nach einer Reihe von Unternehmensmaßnahmen:

  • 12 Millionen USD IPO (März 2024) und 4,5 Millionen USD Folgeangebot (September 2024).
  • Sekundärnotierungen in Frankfurt und Stuttgart (Juni 2024) sowie mehrere neue Tochtergesellschaften (BVI und Singapur) zur Unterstützung der Expansion.
  • 40 % Beteiligung an Atoll Discovery (Juni 2025), bezahlt mit 4,85 Millionen Ryde-Aktien.

ұäڳٲü. Ryde ist eine Holdinggesellschaft auf den Cayman Islands, deren operative Tochtergesellschaften in Singapur eine „Super-Mobilitäts-App� betreiben, die Carpooling, Ride-Hailing (RydeX, RydeXL, RydeLUXE, RydePET, RydeTAXI) und schnelle Paketzustellung (RydeSEND) anbietet. Zu den wichtigsten Stärken zählen eine Dual-Segment-Plattform, skalierbare Technologie und erfahrenes Management.

Wesentliche Risiken im Prospekt:

  • Frühe Wachstumsphase und anhaltende Verluste; Profitabilität hängt von der Reduzierung von Anreizen für Fahrer und Verbraucher ab.
  • Intensiver Wettbewerb durch Grab, Gojek, ComfortDelGro, Lalamove und andere.
  • Regulatorische Unsicherheiten (Platform Workers Act 2024, Fahrerklassifizierung, Datenschutz, AML, LTA-Lizenzen).
  • Micro-Cap-Status (0,32 USD Aktienkurs), potenzielle NYSE American-Listing-Compliance-Herausforderungen und Verwässerung durch Warrants, Wiederverkaufsaktien und zukünftige Angebote.
  • Technologie-, Cybersecurity- und Markenreputationsrisiken, die in Ride-Hailing- und Zustellmodellen inhärent sind.

Verwendung der Erlöse wird in zukünftigen Prospektergänzungen detailliert, typische Zwecke sind jedoch Betriebskapital, Technologieinvestitionen und potenzielle Akquisitionen. Die Fähigkeit des Unternehmens, die vollen 100 Millionen USD zu nutzen, hängt von einer deutlichen Verbesserung der Marktkapitalisierung oder einem Uplisting ab.

Insgesamt positioniert das F-3 Ryde, um schnell zusätzliches Kapital zu beschaffen, die Warrant-Abdeckung fortzusetzen und Aktionärsliquidität zu ermöglichen, während erhebliche wettbewerbliche, operative und regulatorische Herausforderungen hervorgehoben werden, die Investoren abwägen müssen.

Filed Pursuant to Rule 424(b)(3)

Registration No. 333-284606

PROSPECTUS SUPPLEMENT

(to Prospectus dated February 5, 2025)

274,666 American Depositary Shares representing

137,333,300

Ordinary Shares

 

LOGO

Kazia Therapeutics Limited

 

 

This prospectus supplement is being filed to update and supplement the information contained in the prospectus dated February 5, 2025 (the “Prospectus”), which forms a part of our Registration Statement on Form F-1 (Registration No. 333-284606), with the information contained in our current report on Form 6-K, furnished to the Securities and Exchange Commission on July 9, 2025 (the “July 9, 2025 Form 6-K”). Accordingly, we have attached the July 9, 2025 Form 6-K to this prospectus supplement.

This prospectus supplement updates and supplements the information in the Prospectus and is not complete without, and may not be delivered or utilized except in combination with, the Prospectus, including any amendments or supplements thereto. This prospectus supplement should be read in conjunction with the Prospectus and if there is any inconsistency between the information in the Prospectus and this prospectus supplement, you should rely on the information in this prospectus supplement.

The ADSs are listed on The Nasdaq Capital Market (“Nasdaq”) under the symbol “KZIA.” On July 8, 2025, the last reported sale price of the ADSs on Nasdaq was $6.825 per ADS.

 

 

Investing in our securities involves a high degree of risk. See “Risk Factors” beginning on page 9 of the Prospectus and the “Risk Factors” in “Item 3. Key Information—D. Risk Factors” of our most recent Annual Report on Form 20-F, which is incorporated by reference in the Prospectus, as well as in any other recently filed reports and, if any, in any applicable prospectus supplement.

Neither the Securities and Exchange Commission nor any state securities commission has approved or disapproved of these securities or passed upon the adequacy or accuracy of the Prospectus or this prospectus supplement. Any representation to the contrary is a criminal offense.

 

 

The date of this prospectus supplement is July 9, 2025


 
 

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

 

 

Form 6-K

 

 

REPORT OF FOREIGN PRIVATE ISSUER

PURSUANT TO RULE 13a-16 OR 15d-16

UNDER THE SECURITIES EXCHANGE ACT OF 1934

For the month of July, 2025

Commission File Number 000-29962

 

 

Kazia Therapeutics Limited

(Translation of registrant’s name into English)

 

 

Three International Towers Level 24 300 Barangaroo Avenue Sydney NSW 2000

(Address of principal executive office)

 

 

Indicate by check mark whether the registrant files or will file annual reports under cover of Form 20-F or Form 40-F.

Form 20-F ☒   Form 40-F ☐

Indicate by check mark if the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule 101(b)(1): ☐

Indicate by check mark if the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule 101(b)(7): ☐

 

 
 


INFORMATION CONTAINED IN THIS FORM 6-K REPORT

On July 9, 2025, Kazia Therapeutics Limited (the “Company”) issued a press release titled “Kazia Therapeutics Reports Early Efficacy Data from First Triple-Negative Breast Cancer Patient Receiving Paxalisib Combination Regimen achieving >50% Reduction in Circulating Tumor Cells in Phase 1b Trial”. A copy of this release is attached hereto as Exhibit 99.1 and is incorporated herein by reference.

The Company hereby incorporates by reference the information contained herein, including Exhibit 99.1, except for the quote of Dr. John Friend, Chief Executive Officer of the Company, contained in Exhibit 99.1, into the Company’s registration statements on Form F-3 (File No. 333-276091 and 333-281937).

EXHIBIT LIST

 

Exhibit    Description
99.1    Press Release of Kazia Therapeutics Limited dated July 9, 2025


SIGNATURE

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

 

Kazia Therapeutics Limited (Registrant)

/s/ John Friend

John Friend
Chief Executive Officer
Date: 9 July 2025


Exhibit 99.1

Kazia Therapeutics Reports Early Efficacy Data from First Triple-Negative Breast Cancer Patient Receiving Paxalisib Combination Regimen achieving >50% Reduction in Circulating Tumor Cells in Phase 1b Trial

Kazia Therapeutics (NASDAQ: KZIA) is pleased to announce preliminary results from the first patient in its Phase 1b trial evaluating a combination regimen of Paxalisib, pembrolizumab (Keytruda®), and standard chemotherapy after completing Cycle 1 (21 days) of dosing. The patient, a 61-year-old woman with metastatic triple-negative breast cancer localized to the left upper lobe of the lung, has shown highly encouraging preliminary results at 21 days, with a >50% reduction in circulating tumor cells (CTCs) and a notable decrease in CTC clusters.

The early data in this first patient closely mirror the mechanistic preclinical findings published in Molecular Cancer Therapeutics (https://aacrjournals.org/mct/article/doi/10.1158/1535-7163.MCT-24-0693/762979/Depleting-the-Action-of-EZH2-through-PI3K-mTOR), which highlight that Paxalisib, when combined with immunotherapy, significantly disrupted both single CTCs and multicellular clusters in preclinical models.

Key Highlights

- Patient Profile: 61-year-old female, metastatic triple-negative breast cancer (lung metastasis).

- Investigational Regimen: Paxalisib, pembrolizumab, and chemotherapy.

- Results at Day 21 (End-of-Cycle 1):

 

   

>50% reduction in total CTC count.

 

   

Comparable reduction in CTC clusters—these aggregates are associated with heightened metastatic potential.

 

   

Reduction in the mesenchymal phenotype of the remaining CTCs; this phenotype is one of the hallmarks of aggressive metastatic seeding cancer cells.

 

   

First-in-human data support potential for potent CTC mobilization suppression by this combination.


Clinical Significance of Patient Data

CTC clusters have long been recognized as critical mediators of metastasis and markers of poor prognosis. They are known to resist apoptosis, evade immune detection, and seed new tumor sites with exceptional efficiency. Notably, standard chemotherapy has been shown in some studies to transiently increase CTC and cluster counts within the first cycle, with levels sometimes doubling before normalizing after cycle two. In contrast, immunotherapy alone has demonstrated variable impact, often showing delayed or modest effects on CTCs, likely due to immune-mediated mechanisms over weeks to months.

In this case, the combination regimen of Paxalisib and immunotherapy achieved a rapid reduction in both CTC numbers and clusters as well as a reduction in the mesenchymal phenotype—an outcome not typically seen with chemotherapy or immunotherapy alone after only 21 days of treatment. This early clinical data reflects mechanistic synergy consistent with the preclinical data described in the MCT manuscript.

Dr. John Friend, MD, Chief Executive Officer of Kazia Therapeutics, said “It is very exciting to see our extensive preclinical research translate into such positive early data in this first patient receiving a combination of Paxalisib and immunotherapy. The degree of reduction in tumor cell dissemination markers in just 21 days gives us strong reason for optimism as we continue this clinical trial.”

Dr. Friend continued “CTC clusters are emerging as key drivers of metastatic spread—they’re 20–100X more efficient at seeding than single CTCs—and the sharp decline we’re seeing is truly encouraging. We believe this combination may offer a meaningful early intervention against systemic disease progression.”

Next Steps

- Explore potential relationship between CTC kinetics and radiographic responses

- Enrollment continues in the Phase Ib study, expanding cohort size to assess safety, tolerability, and pharmacodynamics

- Planned comprehensive analysis of immune microenvironment and CTC kinetics across all patients through serial monitoring

- Longer-term follow-up will include imaging, progression-free survival, and assessment of correlation with molecular biomarkers

For investor and media, please contact Alex Star, Managing Director LifeSci Advisors LLC, [email protected], +1-201-786-8795.

About Kazia Therapeutics Limited

Kazia Therapeutics Limited (NASDAQ: KZIA) is an oncology-focused drug development company, based in Sydney, Australia. Our lead program is paxalisib, an investigational


brain penetrant inhibitor of the PI3K / Akt / mTOR pathway, which is being developed to treat multiple forms of cancer. Licensed from Genentech in late 2016, paxalisib is or has been the subject of ten clinical trials in this disease. A completed Phase 2/3 study in glioblastoma (GBM-Agile) was reported in 2024 and discussions are ongoing for designing and executing a pivotal registrational study in pursuit of a standard approval. Other clinical trials involving paxalisib are ongoing in advanced breast cancer, brain metastases, diffuse midline gliomas, and primary CNS lymphoma, with several of these trials having reported encouraging interim data. Paxalisib was granted Orphan Drug Designation for glioblastoma by the FDA in February 2018, and Fast Track Designation (FTD) for glioblastoma by the FDA in August 2020. Paxalisib was also granted FTD in July 2023 for the treatment of solid tumour brain metastases harboring PI3K pathway mutations in combination with radiation therapy. In addition, paxalisib was granted Rare Pediatric Disease Designation and Orphan Drug Designation by the FDA for diffuse intrinsic pontine glioma in August 2020, and for atypical teratoid / rhabdoid tumours in June 2022 and July 2022, respectively. Kazia is also developing EVT801, a small molecule inhibitor of VEGFR3, which was licensed from Evotec SE in April 2021. Preclinical data has shown EVT801 to be active against a broad range of tumour types and has provided evidence of synergy with immuno-oncology agents. A Phase I study has been completed and preliminary data was presented at 15th Biennial Ovarian Cancer Research Symposium in September 2024. For more information, please visit www.kaziatherapeutics.com or follow us on X @KaziaTx.

Forward-Looking Statements

This announcement may contain forward-looking statements, which can generally be identified as such by the use of words such as “may,” “will,” “estimate,” “future,” “forward,” “anticipate,” or other similar words. Any statement describing Kazia’s future plans, strategies, intentions, expectations, objectives, goals or prospects, and other statements that are not historical facts, are also forward looking statements, including, but not limited to, statements regarding: the timing for results and data related to Kazia’s clinical and preclinical trials, Kazia’s strategy and plans with respect to its paxalisib program, the potential results of its Phase 1b clinical trial evaluating paxalisib in combination with olaparib or pembrolizumab for patients with advanced breast cancer, the potential benefits of paxalisib as an investigational PI3K/mTOR inhibitor, timing for any regulatory submissions or discussions with regulatory agencies, the potential market opportunity for paxalisib and Kazia’s intent and efforts to regain and/or maintain compliance with the applicable Nasdaq continued listing requirements and standards. Such statements are based on Kazia’s current expectations and projections about future events and future trends affecting its business and are subject to certain risks and uncertainties that could cause actual results to differ materially from those anticipated in the forward-looking statements, including risks and uncertainties associated with clinical and preclinical trials and product development, including the risk that interim or early data may not be consistent with final data, risks related to regulatory approvals, risks related to the impact


of global economic conditions, and risks related to Kazia’s ability to regain and/or maintain compliance with the applicable Nasdaq continued listing requirements and standards. These and other risks and uncertainties are described more fully in Kazia’s Annual Report, filed on form 20-F with the SEC, and in subsequent filings with the United States Securities and Exchange Commission. Kazia undertakes no obligation to publicly update any forward-looking statement, whether as a result of new information, future events, or otherwise, except as required under applicable law. You should not place undue reliance on these forward-looking statements, which apply only as of the date of this announcement.

This announcement was authorized for release by Dr John Friend, CEO

FAQ

What is Ryde Group’s (RYDE) shelf registration size?

The Form F-3 allows Ryde to issue up to US$100 million in securities over time.

How many shares could be sold by the existing shareholder?

Octava Fund Ltd may resell up to 8,030,738 Class A ordinary shares under the prospectus.

What is the public float limitation on new primary sales?

Because Ryde’s public float is only US$4.768 million, SEC Rule I.B.5 caps new primary sales to about US$1.6 million in any 12-month period.

How many shares are underlying outstanding warrants?

There are 5.3 million Class A shares issuable upon exercise of public warrants sold in Sept 2024.

Will Ryde receive proceeds from the resale shares?

No. The company will not receive any proceeds from Octava Fund’s resale, though it will bear certain registration expenses.

Where does Ryde conduct its core operations?

Operations are run by subsidiaries in Singapore; Ryde Group Ltd is a Cayman holding company.

Why is the filing important for investors?

It signals Ryde’s intent to raise additional capital, but also highlights dilution risk and extensive regulatory and competitive challenges.
Kazia Therapeuti

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Biotechnology
Pharmaceutical Preparations
Australia
NEW SOUTH WALES 2113