Other Events
On June 18, 2025, NuCana plc (the “Company”) received a written notification (the “Notice”) from the Listing Qualifications Department
of The Nasdaq Stock Market, LLC (“Nasdaq”) notifying the Company that, for the preceding 30 consecutive trading days, the closing bid price of its American Depositary Shares (“ADSs”) was below the $1.00 per share minimum bid
price requirement for continued inclusion on The Nasdaq Capital Market pursuant to Nasdaq Listing Rule 5550(a)(2) (the “Bid Price Requirement”). This Notice has no immediate effect on the listing of the Company’s ADSs, which continue
to trade on The Nasdaq Capital Market under the symbol “NCNA”.
In accordance with Nasdaq Listing Rule 5810(c)(3)(A), the Company has until
December 15, 2025 (the “Compliance Date”) to regain compliance with the Bid Price Requirement. According to the Notice, if the closing bid price of the Company’s ADSs is least $1.00 per share for a minimum of 10 consecutive
business days before the Compliance Date, Nasdaq will provide written notification that the Company has achieved compliance with the Bid Price Requirement and its ADSs will continue to be eligible for listing on The Nasdaq Capital Market.
If the Company is not able to cure the deficiency within the 180-day compliance period, or any extension that
Nasdaq may grant in its sole discretion, Nasdaq will provide notice that the Company’s ADSs will be subject to delisting. The Company would then be entitled to appeal that determination to a Nasdaq Listing Qualifications Panel (the
“Panel”). However, there can be no assurance that, if the Company receives a delisting notice and appeals the delisting determination by Nasdaq to the Panel, such appeal would be successful.
The Company intends to actively monitor the closing bid price of its ADSs and may, if appropriate, consider implementing available options to regain
compliance with the Bid Price Requirement under the Nasdaq Listing Rules.
The information in this Form 6-K shall
be deemed to be incorporated by reference into the registration statements on Form F-3, as amended (File Number 333-281576) and Form
S-8 (File Number 333-223476 and File Number 333-248135), and related prospectuses, as such registration statements and
prospectuses may be amended from time to time, and to be a part thereof from the date on which this report is filed, to the extent not superseded by documents or reports subsequently filed or furnished.
