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Protagonist Ther SEC Filings

PTGX NASDAQ

Welcome to our dedicated page for Protagonist Ther SEC filings (Ticker: PTGX), a comprehensive resource for investors and traders seeking official regulatory documents including 10-K annual reports, 10-Q quarterly earnings, 8-K material events, and insider trading forms.

Decoding Protagonist Therapeutics� (PTGX) filings—rich with peptide-science jargon, cash-runway disclosures, and collaboration milestones—can be overwhelming. Whether you’re scanning a sudden 8-K or tracing capital raises, the information you need hides in technical detail. That’s why investors search for “understanding Protagonist Therapeutics SEC documents with AI� and “Protagonist Therapeutics SEC filings explained simply.�

Stock Titan turns that challenge into clarity. Our platform delivers AI-powered summaries that highlight trial updates, partnership economics, and risk factors inside every Protagonist Therapeutics annual report 10-K simplified, each Protagonist Therapeutics quarterly earnings report 10-Q filing, and even the briefest Protagonist Therapeutics 8-K material events explained. AGÕæÈ˹ٷ½-time alerts flag Protagonist Therapeutics Form 4 insider transactions real-time, so you never miss new Protagonist Therapeutics executive stock transactions Form 4. Need detail? Click into a filing and our expert notes walk you straight to cash-position tables, IL-23 program costs, or board-level pay disclosures from the Protagonist Therapeutics proxy statement executive compensation section.

Use these insights to act faster: compare revenue from milestone payments with R&D burn in our Protagonist Therapeutics earnings report filing analysis; monitor Protagonist Therapeutics insider trading Form 4 transactions ahead of data readouts; or archive every disclosure for audits. With comprehensive coverage of all forms�10-K, 10-Q, 8-K, S-3, Schedule 13G—and continuous EDGAR updates, Stock Titan equips you to follow this clinical-stage biotech’s journey from lab bench to commercial launch, without wading through hundreds of pages on your own.

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Protagonist Therapeutics (PTGX) Form 4: President & CEO Dr. Dinesh V. Patel settled 25,000 performance stock units on 07/21/25 at a cost basis of $0 after the company met pre-set corporate objectives.

To cover related tax obligations, 12,859 shares were immediately sold at a weighted-average price of $54.86. Additional discretionary sales followed: 22,065 shares on 07/22/25 at $55.05 and 17,520 shares on 07/23/25 at $54.79. In total, 52,444 shares were sold for gross proceeds of roughly $2.9 million, trimming Patel’s direct ownership from 583,462 to 531,018 shares—a reduction of about 9%.

No derivative transactions were reported. While the PSU vesting signals successful execution of 2021-vintage performance goals, the scale of secondary sales may draw investor attention to potential insider-sentiment shifts. Patel remains both a director and the largest named executive insider holder.

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Protagonist Therapeutics, Inc. (PTGX) filed a Form 144 indicating an intended sale of 50,000 common shares through J.P. Morgan Securities on or after 22 Jul 2025. The shares were acquired via six option exercises between Feb 2020 and Mar 2024 and represent roughly 0.08 % of the 61.98 million shares outstanding. The planned transaction carries an aggregate market value of about $2.76 million based on the filing’s reference price. No prior sales were reported in the past three months, and the filer affirmed awareness of no undisclosed material adverse information. While Form 144 only signals intent—not certainty—of sale, it provides investors with advance notice of potential insider liquidity activity.

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Protagonist Therapeutics (NASDAQ:PTGX) filed an 8-K reporting the final voting results of its 2025 Annual Meeting held on June 20, 2025.

  • Directors elected: Harold E. Selick, Ph.D. (44.8 M for / 9.2 M withheld) and Bryan Giraudo (42.5 M for / 11.5 M withheld) to serve until 2028.
  • Say-on-Pay: Executive compensation approved with 50.8 M votes for (92.6% of votes cast).
  • Auditor ratification: Ernst & Young LLP confirmed with 55.5 M votes for (99.1%).

No other matters were brought before shareholders, and the meeting produced routine outcomes with no material corporate changes.

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FAQ

What is the current stock price of Protagonist Ther (PTGX)?

The current stock price of Protagonist Ther (PTGX) is $55.15 as of July 25, 2025.

What is the market cap of Protagonist Ther (PTGX)?

The market cap of Protagonist Ther (PTGX) is approximately 3.4B.

What is the core focus of Protagonist Therapeutics?

Protagonist Therapeutics is dedicated to discovering and developing novel, peptide-based therapeutics that address unmet medical needs, particularly for inflammatory, autoimmune, and hematologic disorders.

What differentiates their approach to drug development?

Their proprietary constrained peptide platform enables the design of stable, oral drug candidates that mimic the efficacy of injectable antibodies while offering the convenience and potential safety benefits of oral administration.

Which key therapeutic candidates are in their pipeline?

The company’s pipeline includes icotrokinra, an oral IL-23 receptor antagonist targeting inflammatory diseases like psoriasis and ulcerative colitis, and rusfertide, a hepcidin mimetic aimed at treating polycythemia vera.

How does Protagonist generate revenue?

Revenue is generated through strategic collaborations and licensing agreements with major pharmaceutical companies, which include milestone payments and shared development costs in advancing their clinical candidates.

What are the strategic collaborations that support its development efforts?

The company collaborates with industry leaders such as Takeda Pharmaceuticals and Johnson & Johnson, which provide vital resources and expertise to further clinical development and market penetration of its drug candidates.

How does the company's technology platform enhance its drug candidates?

The platform allows for the rapid discovery and optimization of constrained peptides, yielding drug candidates with improved bioavailability, stability, and targeted action that can potentially transform treatment paradigms.

What clinical conditions are being targeted by its products?

Protagonist focuses on conditions such as moderate-to-severe plaque psoriasis, ulcerative colitis, and polycythemia vera, leveraging its oral peptide approach to address these complex clinical challenges.

How does Protagonist position itself in the competitive biopharmaceutical landscape?

By combining innovative oral peptide technology with strong strategic partnerships, the company carves out a unique niche that contrasts with traditional injectable therapies, positioning itself as an emerging player in next-generation therapeutics.
Protagonist Ther

NASDAQ:PTGX

PTGX Rankings

PTGX Stock Data

3.36B
60.15M
1.38%
105.26%
7.93%
Biotechnology
Pharmaceutical Preparations
United States
NEWARK