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[Form 4] Septerna, Inc. Insider Trading Activity

Filing Impact
(Low)
Filing Sentiment
(Neutral)
Form Type
4
Rhea-AI Filing Summary

Septerna, Inc. insider Daniel D. Long, the company's SVP of Drug Discovery, received a grant of stock options allowing him to purchase 30,000 shares of Septerna common stock at an exercise price of $11.70 per share.

The option award was recorded with a transaction date of 08/07/2025, carries an expiration date of 08/06/2035, and vests in monthly installments equal to 1/48th of the total award beginning August 1, 2025, subject to continued service. The filing shows the reporting person holds 30,000 options following the transaction and lists the ownership form as direct.

Septerna, Inc. il dirigente interno Daniel D. Long, vicepresidente senior per la scoperta di farmaci (SVP), ha ricevuto un'assegnazione di opzioni su azioni che gli consente di acquistare 30,000 azioni ordinarie di Septerna al prezzo di esercizio di $11.70 per azione.

L'assegnazione delle opzioni è registrata con data di operazione 08/07/2025, ha scadenza il 08/06/2035 e matura in rate mensili pari a 1/48 del totale a partire dal 1 agosto 2025, subordinata alla continuazione del servizio. Il deposito indica che la persona segnalante detiene 30,000 opzioni dopo l'operazione e dichiara la forma di proprietà come diretta.

Septerna, Inc. el directivo interno Daniel D. Long, vicepresidente senior de Drug Discovery, recibió una concesión de opciones sobre acciones que le permiten comprar 30,000 acciones ordinarias de Septerna a un precio de ejercicio de $11.70 por acción.

La adjudicación figura con fecha de operación 08/07/2025, vence el 08/06/2035 y se consolida en cuotas mensuales iguales a 1/48 del total a partir del 1 de agosto de 2025, sujeto a la continuidad del servicio. La presentación muestra que la persona informante posee 30,000 opciones tras la transacción y registra la forma de propiedad como directa.

Septerna, Inc. ë‚´ë¶€ìž� Daniel D. Long(신약 발굴 ë¶€ë¬� SVP)ì€ 30,000주를 주당 행사 ê°€ê²� $11.70ì—� 매수í•� ìˆ� 있는 스톡 옵션ì� 부여받았습니다.

옵션 부여는 거래ì¼ì„ 08/07/2025ë¡� 기재했으ë©� 만료ì¼ì€ 08/06/2035ì´ê³ , 2025ë…� 8ì›� 1ì�ë¶€í„� ì „ì²´ì� 1/48ì”� 매월 베스팅ë˜ë©� ê³„ì† ê·¼ë¬´ê°€ 조건입니ë‹�. 제출서류ì—� 따르ë©� ë³´ê³ ì¸ì€ 거래 í›� 30,000ê°œì˜ ì˜µì…˜ì� 보유하고 있으ë©� 소유 형태ëŠ� ì§ì ‘ 보유ë¡� 기재ë˜ì–´ 있습니다.

Septerna, Inc. l'initié Daniel D. Long, vice‑président senior en Drug Discovery, a reçu une attribution d'options sur actions lui permettant d'acheter 30,000 actions ordinaires de Septerna au prix d'exercice de $11.70 par action.

L'attribution est enregistrée avec une date de transaction du 08/07/2025, expire le 08/06/2035 et se acquiert par mensualités égales à 1/48 du total à partir du 1er août 2025, sous réserve de la poursuite du service. Le dépôt indique que la personne déclarante détient 30,000 options après la transaction et précise que la forme de propriété est directe.

Septerna, Inc.-Insider Daniel D. Long, Senior Vice President für Drug Discovery, erhielt eine Gewährung von Aktienoptionen, die ihm den Kauf von 30,000 Septerna-Stammaktien zum Ausübungspreis von $11.70 je Aktie ermöglichen.

Die Optionszuteilung ist mit dem Transaktionsdatum 08/07/2025 erfasst, läuft am 08/06/2035 ab und wird in monatlichen Raten fällig, die jeweils 1/48 des Gesamtbetrags entsprechen, beginnend am 1. August 2025, vorbehaltlich fortgesetzter Dienstzeit. Die Meldung zeigt, dass die meldepflichtige Person nach der Transaktion 30,000 Optionen hält und die Eigentumsform als direkt angibt.

Positive
  • Clear, time-based vesting schedule: 1/48th monthly vesting beginning 08/01/2025 supports retention incentives
  • Ten-year term to expiration: expiration date 08/06/2035 aligns with long-term alignment between executive and shareholders
  • Exercise price disclosed: exercise price is explicitly listed as $11.70, providing transparency on strike terms
Negative
  • None.

Insights

TL;DR: Routine officer option grant; limited immediate market impact but aligns executive incentives long-term.

The Form 4 documents a standard option grant to an executive: 30,000 options at a $11.70 exercise price with a 10-year contractual horizon to 08/06/2035 and a time-based vesting schedule of 1/48th monthly beginning 08/01/2025. From a securities perspective, this is a compensation-related issuance that typically dilutes over time as vested options are exercised; however, the filing alone does not quantify any immediate dilution relative to outstanding share count or indicate material change to financials.

TL;DR: Governance-wise this is a standard retention-style grant with clear vesting; no red flags in the disclosure itself.

The disclosure identifies the reporting person as an officer (SVP, Drug Discovery) and specifies a monthly vesting cadence (1/48th) tied to continued service, which is consistent with long-term incentive practices. The terms shown—exercise price of $11.70, 30,000 option quantity, and expiration in 2035—are explicit. The filing does not show any acceleration clauses or unusual transfer/indirect ownership arrangements.

Septerna, Inc. il dirigente interno Daniel D. Long, vicepresidente senior per la scoperta di farmaci (SVP), ha ricevuto un'assegnazione di opzioni su azioni che gli consente di acquistare 30,000 azioni ordinarie di Septerna al prezzo di esercizio di $11.70 per azione.

L'assegnazione delle opzioni è registrata con data di operazione 08/07/2025, ha scadenza il 08/06/2035 e matura in rate mensili pari a 1/48 del totale a partire dal 1 agosto 2025, subordinata alla continuazione del servizio. Il deposito indica che la persona segnalante detiene 30,000 opzioni dopo l'operazione e dichiara la forma di proprietà come diretta.

Septerna, Inc. el directivo interno Daniel D. Long, vicepresidente senior de Drug Discovery, recibió una concesión de opciones sobre acciones que le permiten comprar 30,000 acciones ordinarias de Septerna a un precio de ejercicio de $11.70 por acción.

La adjudicación figura con fecha de operación 08/07/2025, vence el 08/06/2035 y se consolida en cuotas mensuales iguales a 1/48 del total a partir del 1 de agosto de 2025, sujeto a la continuidad del servicio. La presentación muestra que la persona informante posee 30,000 opciones tras la transacción y registra la forma de propiedad como directa.

Septerna, Inc. ë‚´ë¶€ìž� Daniel D. Long(신약 발굴 ë¶€ë¬� SVP)ì€ 30,000주를 주당 행사 ê°€ê²� $11.70ì—� 매수í•� ìˆ� 있는 스톡 옵션ì� 부여받았습니다.

옵션 부여는 거래ì¼ì„ 08/07/2025ë¡� 기재했으ë©� 만료ì¼ì€ 08/06/2035ì´ê³ , 2025ë…� 8ì›� 1ì�ë¶€í„� ì „ì²´ì� 1/48ì”� 매월 베스팅ë˜ë©� ê³„ì† ê·¼ë¬´ê°€ 조건입니ë‹�. 제출서류ì—� 따르ë©� ë³´ê³ ì¸ì€ 거래 í›� 30,000ê°œì˜ ì˜µì…˜ì� 보유하고 있으ë©� 소유 형태ëŠ� ì§ì ‘ 보유ë¡� 기재ë˜ì–´ 있습니다.

Septerna, Inc. l'initié Daniel D. Long, vice‑président senior en Drug Discovery, a reçu une attribution d'options sur actions lui permettant d'acheter 30,000 actions ordinaires de Septerna au prix d'exercice de $11.70 par action.

L'attribution est enregistrée avec une date de transaction du 08/07/2025, expire le 08/06/2035 et se acquiert par mensualités égales à 1/48 du total à partir du 1er août 2025, sous réserve de la poursuite du service. Le dépôt indique que la personne déclarante détient 30,000 options après la transaction et précise que la forme de propriété est directe.

Septerna, Inc.-Insider Daniel D. Long, Senior Vice President für Drug Discovery, erhielt eine Gewährung von Aktienoptionen, die ihm den Kauf von 30,000 Septerna-Stammaktien zum Ausübungspreis von $11.70 je Aktie ermöglichen.

Die Optionszuteilung ist mit dem Transaktionsdatum 08/07/2025 erfasst, läuft am 08/06/2035 ab und wird in monatlichen Raten fällig, die jeweils 1/48 des Gesamtbetrags entsprechen, beginnend am 1. August 2025, vorbehaltlich fortgesetzter Dienstzeit. Die Meldung zeigt, dass die meldepflichtige Person nach der Transaktion 30,000 Optionen hält und die Eigentumsform als direkt angibt.

SEC Form 4
FORM 4 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number: 3235-0287
Estimated average burden
hours per response: 0.5
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.
1. Name and Address of Reporting Person*
Long Daniel D.

(Last) (First) (Middle)
C/O SEPTERNA, INC.
250 EAST GRAND AVENUE

(Street)
SOUTH SAN FRANCISCO CA 94080

(City) (State) (Zip)
2. Issuer Name and Ticker or Trading Symbol
Septerna, Inc. [ SEPN ]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
Director 10% Owner
X Officer (give title below) Other (specify below)
SVP, Drug Discovery
3. Date of Earliest Transaction (Month/Day/Year)
08/07/2025
4. If Amendment, Date of Original Filed (Month/Day/Year)
6. Individual or Joint/Group Filing (Check Applicable Line)
X Form filed by One Reporting Person
Form filed by More than One Reporting Person
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year) 7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Stock Option (Right to Buy) $11.7 08/07/2025 A 30,000 (1) 08/06/2035 Common Stock 30,000 $0 30,000 D
Explanation of Responses:
1. 1/48th of the shares subject to such option shall vest and become exercisable in substantially equal monthly installments on each monthly anniversary of August 1, 2025, subject to the Reporting Person's continuous service to the Issuer on each such date.
/s/ Ran Xiao, Attorney-in-Fact 08/11/2025
** Signature of Reporting Person Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.

FAQ

What transaction is reported in the Septerna (SEPN) Form 4?

The Form 4 reports an option grant: 30,000 stock options to purchase common stock at an exercise price of $11.70.

Who is the reporting person on the Form 4 for SEPN?

The reporting person is Daniel D. Long, identified as SVP, Drug Discovery at Septerna.

When does the option vest and when does it expire?

Vesting is 1/48th of the award monthly beginning August 1, 2025, and the options expire on August 6, 2035.

How many derivative securities does Daniel Long beneficially own after the transaction?

The filing shows 30,000 derivative securities (options) beneficially owned following the reported transaction, held in a direct ownership form.

What was the transaction date reported on the Form 4?

The transaction date listed in the filing is 08/07/2025.
Septerna, Inc.

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Biotechnology
Pharmaceutical Preparations
United States
SOUTH SAN FRANCISCO