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[SCHEDULE 13G/A] Entrada Therapeutics, Inc. SEC Filing

Filing Impact
(Low)
Filing Sentiment
(Neutral)
Form Type
SCHEDULE 13G/A
Rhea-AI Filing Summary

Janus Henderson Group plc reports beneficial ownership of 1,521,281 shares of Entrada Therapeutics common stock, representing 4.0% of the class. The filing states Janus Henderson has no sole voting or dispositive power and shared voting and dispositive power over all reported shares.

The filing identifies certain indirect subsidiaries (including JHIUS, JHIUKL and JHIAIFML) as registered investment advisers furnishing advice to Managed Portfolios and includes a certification that the securities are held in the ordinary course of business and not for the purpose of changing or influencing control of the issuer.

Janus Henderson Group plc dichiara la titolarità beneficiaria di 1,521,281 azioni ordinarie di Entrada Therapeutics, pari al 4.0% della classe. La comunicazione indica che Janus Henderson non ha potere di voto né di disposizione in via esclusiva e detiene poteri di voto e di disposizione condivisi su tutte le azioni segnalate.

La pratica identifica alcune controllate indirette (tra cui JHIUS, JHIUKL e JHIAIFML) come consulenti di investimento registrati che forniscono indicazioni ai Portafogli Gestiti e include una certificazione che i titoli sono detenuti nell'ordinario corso dell'attività e non allo scopo di modificare o influenzare il controllo dell'emittente.

Janus Henderson Group plc informa la propiedad beneficiaria de 1,521,281 acciones ordinarias de Entrada Therapeutics, que representan el 4.0% de la clase. La presentación indica que Janus Henderson no tiene poder de voto ni de disposición exclusivo y posee poderes de voto y de disposición compartidos sobre todas las acciones declaradas.

La presentación identifica determinadas filiales indirectas (incluidas JHIUS, JHIUKL y JHIAIFML) como asesores de inversión registrados que prestan asesoramiento a Carteras Gestionadas e incluye una certificación de que los valores se mantienen en el curso ordinario del negocio y no con el propósito de cambiar o influir en el control del emisor.

Janus Henderson Group plcëŠ� Entrada Therapeuticsì� 보통ì£� 1,521,281주를 실소유하ê³� 있으ë©�, ì´ëŠ” í´ëž˜ìŠ¤ì˜ 4.0%ì—� 해당한다ê³� 보고했습니다. 제출서류ì—는 Janus Hendersonì� 단ë…으로 ì˜ê²°ê¶� ë˜ëŠ” ì²˜ë¶„ê¶Œì„ í–‰ì‚¬í•˜ëŠ” 권한ì� 없다ê³� 기재ë˜ì–´ 있으ë©�, ë³´ê³ ë� 모든 주ì‹ì—� 대í•� ì˜ê²°ê¶� ë°� ì²˜ë¶„ê¶Œì„ ê³µë™ìœ¼ë¡œ 보유하고 있다ê³� 명시ë˜ì–´ 있습니다.

서류ëŠ� 특정 ê°„ì ‘ ìžíšŒì‚�(ì˜�: JHIUS, JHIUKL ë°� JHIAIFML)ë¥� ê´€ë¦� í¬íЏí´ë¦¬ì˜¤ì— ìžë¬¸ì� 제공하는 ë“±ë¡ íˆ¬ìžìžë¬¸ì‚¬ë¡œ ì‹ë³„하고 있으ë©�, 해당 ì¦ê¶Œì� 통ìƒì ì¸ ì˜ì—… 과정ì—서 보유ë˜ê³  있으ë©� 발행ì¸ì˜ 지배권ì� 변경하거나 ì˜í–¥ë ¥ì„ 행사하기 위한 목ì ì� 아님ì� ì¸ì¦í•˜ëŠ” ë‚´ìš©ì� í¬í•¨í•˜ê³  있습니다.

Janus Henderson Group plc déclare détenir la propriété bénéficiaire de 1,521,281 actions ordinaires d'Entrada Therapeutics, représentant 4.0% de la catégorie. Le dépôt indique que Janus Henderson n'a aucun pouvoir de vote ou de disposition exclusif et qu'il exerce des pouvoirs de vote et de disposition ±è²¹°ù³Ù²¹²µÃ©²õ sur l'ensemble des actions déclarées.

Le dépôt identifie certaines filiales indirectes (y compris JHIUS, JHIUKL et JHIAIFML) comme conseillers en investissement enregistrés fournissant des conseils aux Portefeuilles Gérés et inclut une certification que les titres sont détenus dans le cours normal des affaires et pas dans le but de modifier ou d'influencer le contrôle de l'émetteur.

Janus Henderson Group plc meldet wirtschaftliches Eigentum an 1,521,281 Aktien von Entrada Therapeutics, was 4.0% der Klasse entspricht. Die Einreichung gibt an, dass Janus Henderson keine alleinigen Stimm- oder Verfügungsbefugnisse besitzt und über alle gemeldeten Aktien geteilte Stimm- und Verfügungsbefugnisse hat.

Die Einreichung benennt bestimmte indirekte Tochtergesellschaften (einschließlich JHIUS, JHIUKL und JHIAIFML) als registrierte Anlageberater, die verwaltete Portfolios beraten, und enthält eine Bestätigung, dass die Wertpapiere im normalen Geschäftsverlauf gehalten werden und nicht zum Zweck der Änderung oder Beeinflussung der Kontrolle des Emittenten dienen.

Positive
  • Discloses 1,521,281 shares (4.0%) beneficially owned, providing clear ownership transparency
  • Reports shared voting and dispositive power with 0 shares held with sole power, clarifying control parameters
  • Identifies the indirect subsidiaries (JHIUS, JHIUKL, JHIAIFML) as registered investment advisers advising Managed Portfolios, explaining the holding structure
  • Includes a certification that the securities are held in the ordinary course of business and not to influence control, clarifying intent
Negative
  • None.

Insights

TL;DR: A disclosed 4.0% passive stake held via adviser subsidiaries shows institutional exposure but no asserted intent to influence control.

The filing documents a 1,521,281-share position representing 4.0% of outstanding common stock, with shared voting and dispositive power and no sole control. Holdings are held through named adviser subsidiaries that provide investment advice to Managed Portfolios, indicating the position is managed on behalf of clients rather than as a controlling stake. The certification reiterates the ordinary-course nature of the holdings. Impact on valuation or governance appears limited based on disclosed facts.

TL;DR: Reporting is compliant and transparent; disclosed shared powers and adviser structure suggest passive, advisory management of the holding.

The schedule identifies Janus Henderson as the reporting person with shared voting and dispositive authority over the reported shares and classifies the entity as IA and HC. The exhibit names a standing power of attorney and specifies indirect subsidiaries (JHIUS, JHIUKL, JHIAIFML) as registered investment advisers advising Managed Portfolios. The filing includes a declaration that the securities are not held to influence issuer control, which is a material statement for governance assessment. Based solely on the document, this disclosure is procedural and does not reflect active governance engagement.

Janus Henderson Group plc dichiara la titolarità beneficiaria di 1,521,281 azioni ordinarie di Entrada Therapeutics, pari al 4.0% della classe. La comunicazione indica che Janus Henderson non ha potere di voto né di disposizione in via esclusiva e detiene poteri di voto e di disposizione condivisi su tutte le azioni segnalate.

La pratica identifica alcune controllate indirette (tra cui JHIUS, JHIUKL e JHIAIFML) come consulenti di investimento registrati che forniscono indicazioni ai Portafogli Gestiti e include una certificazione che i titoli sono detenuti nell'ordinario corso dell'attività e non allo scopo di modificare o influenzare il controllo dell'emittente.

Janus Henderson Group plc informa la propiedad beneficiaria de 1,521,281 acciones ordinarias de Entrada Therapeutics, que representan el 4.0% de la clase. La presentación indica que Janus Henderson no tiene poder de voto ni de disposición exclusivo y posee poderes de voto y de disposición compartidos sobre todas las acciones declaradas.

La presentación identifica determinadas filiales indirectas (incluidas JHIUS, JHIUKL y JHIAIFML) como asesores de inversión registrados que prestan asesoramiento a Carteras Gestionadas e incluye una certificación de que los valores se mantienen en el curso ordinario del negocio y no con el propósito de cambiar o influir en el control del emisor.

Janus Henderson Group plcëŠ� Entrada Therapeuticsì� 보통ì£� 1,521,281주를 실소유하ê³� 있으ë©�, ì´ëŠ” í´ëž˜ìŠ¤ì˜ 4.0%ì—� 해당한다ê³� 보고했습니다. 제출서류ì—는 Janus Hendersonì� 단ë…으로 ì˜ê²°ê¶� ë˜ëŠ” ì²˜ë¶„ê¶Œì„ í–‰ì‚¬í•˜ëŠ” 권한ì� 없다ê³� 기재ë˜ì–´ 있으ë©�, ë³´ê³ ë� 모든 주ì‹ì—� 대í•� ì˜ê²°ê¶� ë°� ì²˜ë¶„ê¶Œì„ ê³µë™ìœ¼ë¡œ 보유하고 있다ê³� 명시ë˜ì–´ 있습니다.

서류ëŠ� 특정 ê°„ì ‘ ìžíšŒì‚�(ì˜�: JHIUS, JHIUKL ë°� JHIAIFML)ë¥� ê´€ë¦� í¬íЏí´ë¦¬ì˜¤ì— ìžë¬¸ì� 제공하는 ë“±ë¡ íˆ¬ìžìžë¬¸ì‚¬ë¡œ ì‹ë³„하고 있으ë©�, 해당 ì¦ê¶Œì� 통ìƒì ì¸ ì˜ì—… 과정ì—서 보유ë˜ê³  있으ë©� 발행ì¸ì˜ 지배권ì� 변경하거나 ì˜í–¥ë ¥ì„ 행사하기 위한 목ì ì� 아님ì� ì¸ì¦í•˜ëŠ” ë‚´ìš©ì� í¬í•¨í•˜ê³  있습니다.

Janus Henderson Group plc déclare détenir la propriété bénéficiaire de 1,521,281 actions ordinaires d'Entrada Therapeutics, représentant 4.0% de la catégorie. Le dépôt indique que Janus Henderson n'a aucun pouvoir de vote ou de disposition exclusif et qu'il exerce des pouvoirs de vote et de disposition ±è²¹°ù³Ù²¹²µÃ©²õ sur l'ensemble des actions déclarées.

Le dépôt identifie certaines filiales indirectes (y compris JHIUS, JHIUKL et JHIAIFML) comme conseillers en investissement enregistrés fournissant des conseils aux Portefeuilles Gérés et inclut une certification que les titres sont détenus dans le cours normal des affaires et pas dans le but de modifier ou d'influencer le contrôle de l'émetteur.

Janus Henderson Group plc meldet wirtschaftliches Eigentum an 1,521,281 Aktien von Entrada Therapeutics, was 4.0% der Klasse entspricht. Die Einreichung gibt an, dass Janus Henderson keine alleinigen Stimm- oder Verfügungsbefugnisse besitzt und über alle gemeldeten Aktien geteilte Stimm- und Verfügungsbefugnisse hat.

Die Einreichung benennt bestimmte indirekte Tochtergesellschaften (einschließlich JHIUS, JHIUKL und JHIAIFML) als registrierte Anlageberater, die verwaltete Portfolios beraten, und enthält eine Bestätigung, dass die Wertpapiere im normalen Geschäftsverlauf gehalten werden und nicht zum Zweck der Änderung oder Beeinflussung der Kontrolle des Emittenten dienen.






Check the appropriate box to designate the rule pursuant to which this Schedule is filed:
Rule 13d-1(b)
Rule 13d-1(c)
Rule 13d-1(d)






SCHEDULE 13G





SCHEDULE 13G



JANUS HENDERSON GROUP PLC
Signature:Kristin Mariani
Name/Title:Head of North America Compliance, CCO
Date:08/14/2025
Exhibit Information

POWER OF ATTORNEY The undersigned, Janus Henderson Group plc ("the Company"), does hereby make, constitute and appoint each of Kristin Mariani and Caroline Barotti acting severally, as its true and lawful attorneys in-fact, for the purpose of, from time to time, executing in its name and on its behalf, whether the Company individually or as representative of others, any and all documents, certificates, instruments, statements, other filings and amendments to the foregoing (collectively, "documents") determined by such person to be necessary or appropriate to comply with ownership or control-person reporting requirements imposed by any United States or non-United States governmental or regulatory authority, including, without limitation, Forms 13D, 13F, 13G and 13H and any amendments to any of the foregoing as may be required to be filed with the Securities and Exchange Commission, and delivering, furnishing or filing any such documents with the appropriate governmental, regulatory authority or other person, and giving and granting to each such attorney-in-fact power and authority to act in the premises as fully and to all intents and purposes as the Company might or could do if personally present by one of its authorized signatories, hereby ratifying and confirming all that said attorney-in-fact shall lawfully do or cause to be done by virtue hereof. Any such determination by an attorney-in-fact named herein shall be conclusively evidenced by such person's execution, delivery, furnishing or filing of the applicable document. This power of attorney shall be valid from the date hereof and shall remain in full force and effect until either revoked in writing by the Company, or, in respect of any attorney-in-fact named herein, until such person ceases to be an employee of the Company or one of its affiliates. IN WITNESS WHEREOF, the undersigned has caused this power of attorney to be executed as of this 9th day of December, 2022. Janus Henderson Group plc By: /s/ Michelle Rosenberg Name: Michelle Rosenberg Title: General Counsel and Company Secretary

FAQ

How many shares of TRDA does Janus Henderson report owning?

The filing reports beneficial ownership of 1,521,281 shares of Entrada Therapeutics common stock.

What percentage of Entrada (TRDA) does Janus Henderson's holding represent?

The reported position represents 4.0% of the class of common stock.

Does Janus Henderson have sole voting or dispositive power over these TRDA shares?

No; the filing shows 0 shares with sole voting or dispositive power and 1,521,281 shares with shared voting and dispositive power.

Through which entities are the TRDA shares held or managed?

The filing identifies indirect subsidiaries including JHIUS, JHIUKL, and JHIAIFML as registered investment advisers furnishing advice to Managed Portfolios.

Does the filing state an intent to influence control of Entrada Therapeutics?

The certification states the securities are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer.

How is the reporting person classified in the filing?

The reporting person is classified as an IA (investment adviser) and HC.
Entrada Therapeutics, Inc.

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Biotechnology
Pharmaceutical Preparations
United States
BOSTON