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Karyopharm Therapeutics Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)

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Karyopharm Therapeutics (Nasdaq: KPTI), a commercial-stage pharmaceutical company focused on cancer therapies, has announced the granting of 666 restricted stock units (RSUs) to two newly-hired employees as of June 30, 2025.

The RSU awards, granted under the Company's 2022 Inducement Stock Incentive Plan, will vest over three years, with 33 1/3% vesting annually. The grants were made in accordance with Nasdaq Listing Rule 5635(c)(4). Additionally, the RSUs include provisions for immediate full vesting in case of employment termination under specific conditions following a change in control event.

Karyopharm Therapeutics (Nasdaq: KPTI), un'azienda farmaceutica in fase commerciale specializzata in terapie oncologiche, ha annunciato la concessione di 666 unità azionarie vincolate (RSU) a due nuovi dipendenti a partire dal 30 giugno 2025.

Le assegnazioni di RSU, concesse nell'ambito del Piano di Incentivazione Azionaria 2022 della Società, matureranno in tre anni, con un 33 1/3% che matura annualmente. Le assegnazioni sono state effettuate in conformità con la Regola di Quotazione Nasdaq 5635(c)(4). Inoltre, le RSU prevedono la maturazione immediata e completa in caso di cessazione del rapporto di lavoro in determinate condizioni successive a un evento di cambio di controllo.

Karyopharm Therapeutics (Nasdaq: KPTI), una empresa farmacéutica en etapa comercial centrada en terapias contra el cáncer, ha anunciado la concesión de 666 unidades restringidas de acciones (RSU) a dos empleados recién contratados a partir del 30 de junio de 2025.

Las concesiones de RSU, otorgadas bajo el Plan de Incentivos de Acciones por Inducción 2022 de la Compañía, se consolidarán durante tres años, con un 33 1/3% consolidándose anualmente. Las concesiones se realizaron de acuerdo con la Regla de Listado Nasdaq 5635(c)(4). Además, las RSU incluyen disposiciones para la consolidación inmediata y total en caso de terminación del empleo bajo condiciones específicas tras un evento de cambio de control.

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ì� RSU ë³´ìƒì€ 회사ì� 2022ë…� ìœ ì¸ ì£¼ì‹ ì¸ì„¼í‹°ë¸Œ 계íšì—� ë”°ë¼ ë¶€ì—¬ë˜ë©�, 3ë…„ì— ê±¸ì³ ë§¤ë…„ 33 1/3%ì”� 베스íŒ�ë©ë‹ˆë‹�. ì� 부여는 나스ë‹� ìƒìž¥ 규칙 5635(c)(4)ì—� ë”°ë¼ ì´ë£¨ì–´ì¡ŒìŠµë‹ˆë‹�. ë˜í•œ, RSUì—는 지배권 ë³€ê²� 사건 í›� 특정 ì¡°ê±´ 하ì—ì„� ê³ ìš© 종료 ì‹� 즉시 ì „ì•¡ 베스팅ë˜ëŠ� ì¡°í•­ì� í¬í•¨ë˜ì–´ 있습니다.

Karyopharm Therapeutics (Nasdaq : KPTI), une société pharmaceutique en phase commerciale spécialisée dans les thérapies contre le cancer, a annoncé l’attribution de 666 unités d’actions restreintes (RSU) à deux nouveaux employés à compter du 30 juin 2025.

Les attributions de RSU, accordées dans le cadre du Plan d’Incitation à l’Actionnariat 2022 de la Société, seront acquises sur une période de trois ans, avec 33 1/3 % acquis chaque année. Les attributions ont été effectuées conformément à la règle de cotation Nasdaq 5635(c)(4). De plus, les RSU comprennent des dispositions pour une acquisition immédiate et totale en cas de cessation d’emploi dans des conditions spécifiques suite à un événement de changement de contrôle.

Karyopharm Therapeutics (Nasdaq: KPTI), ein pharmazeutisches Unternehmen in der kommerziellen Phase mit Schwerpunkt auf Krebstherapien, hat die Gewährung von 666 Restricted Stock Units (RSUs) an zwei neu eingestellte Mitarbeiter zum 30. Juni 2025 bekannt gegeben.

Die RSU-Zuweisungen, die im Rahmen des Inducement Stock Incentive Plans 2022 des Unternehmens gewährt wurden, werden über drei Jahre mit einer jährlichen Vesting-Rate von 33 1/3% freigegeben. Die Zuweisungen erfolgten gemäß der Nasdaq-Listing-Regel 5635(c)(4). Zusätzlich enthalten die RSUs Bestimmungen für eine sofortige vollständige Vesting bei Beendigung des Arbeitsverhältnisses unter bestimmten Bedingungen nach einem Kontrollwechselereignis.

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NEWTON, Mass., July 1, 2025 /PRNewswire/ -- Karyopharm Therapeutics Inc. (Nasdaq: KPTI), a commercial-stage pharmaceutical company pioneering novel cancer therapies, today announced that the Company granted an aggregate of 666 restricted stock units (RSUs) to two newly-hired employees. These RSU awards were granted as of June 30, 2025 (the "Grant Date") pursuant to the Company's 2022 Inducement Stock Incentive Plan, as amended, as inducements material to the new employees entering into employment with Karyopharm in accordance with Nasdaq Listing Rule 5635(c)(4).

Each RSU award will vest over three years, with 33 1/3% of the shares underlying the RSU award vesting on each of the three consecutive anniversaries of the Grant Date. The vesting of each RSU award is subject to the employee's continued service as an employee of, or other service provider to, Karyopharm through the applicable vesting dates.

In addition, each RSU award will be immediately exercisable in full if, on or prior to the first anniversary of the consummation of a "change in control event," the employee's employment is terminated for "good reason" by the employee or terminated without "cause" by Karyopharm (as such terms are defined in the 2022 Inducement Stock Incentive Plan, as amended).

About Karyopharm Therapeutics

Karyopharm Therapeutics Inc. (Nasdaq: KPTI) is a commercial-stage pharmaceutical company whose dedication to pioneering novel cancer therapies is fueled by a belief in the extraordinary strength and courage of patients with cancer. Since its founding, Karyopharm has been an industry leader in oral compounds that address nuclear export dysregulation, a fundamental mechanism of oncogenesis. Karyopharm's lead compound and first­in­class, oral exportin 1 (XPO1) inhibitor, XPOVIO® (selinexor), is approved in the U.S. and marketed by the Company in three oncology indications. It has also received regulatory approvals in various indications in a growing number of ex­U.S. territories and countries, including Europe and the United Kingdom (as NEXPOVIO®) and China. Karyopharm has a focused pipeline targeting indications in multiple high unmet need cancers, including in multiple myeloma, endometrial cancer, myelofibrosis, and diffuse large B-cell lymphoma (DLBCL). For more information about our people, science and pipeline, please visit www.karyopharm.com, and follow us on LinkedIn and on X at @Karyopharm.

XPOVIO® and NEXPOVIO® are registered trademarks of Karyopharm Therapeutics Inc.

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SOURCE Karyopharm Therapeutics Inc.

FAQ

What type of stock awards did Karyopharm Therapeutics (KPTI) grant to new employees in June 2025?

Karyopharm granted 666 restricted stock units (RSUs) to two newly-hired employees as of June 30, 2025.

What is the vesting schedule for Karyopharm's (KPTI) June 2025 RSU grants?

The RSUs will vest over three years, with 33 1/3% of shares vesting on each anniversary of the June 30, 2025 grant date.

Under what conditions can Karyopharm's (KPTI) June 2025 RSU grants become immediately exercisable?

The RSUs become fully exercisable if the employee's employment is terminated for 'good reason' or without 'cause' within one year of a change in control event.

What is the purpose of Karyopharm's (KPTI) June 2025 RSU grants?

The RSUs were granted as inducements material to new employees entering employment with Karyopharm, in accordance with Nasdaq Listing Rule 5635(c)(4).
Karyopharm Therapeutics Inc

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Biotechnology
Pharmaceutical Preparations
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