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Apellis Pharmace SEC Filings

APLS NASDAQ

Welcome to our dedicated page for Apellis Pharmace SEC filings (Ticker: APLS), a comprehensive resource for investors and traders seeking official regulatory documents including 10-K annual reports, 10-Q quarterly earnings, 8-K material events, and insider trading forms.

Apellis Pharmaceuticals� SEC disclosures can span hundreds of pages filled with immunology terms like C3 inhibition, trial cohort data, and royalty math with Swedish Orphan Biovitrum. Finding the cash runway or safety signals for SYFOVRE often means combing through dense footnotes. That complexity is exactly the problem investors face when they ask, “Where do I see Apellis Pharmaceuticals� quarterly earnings report 10-Q filing?� or “How do I track Apellis Pharmaceuticals insider trading Form 4 transactions?�

Stock Titan solves this with AI-powered summaries that translate biotech jargon into clear language. Our platform delivers real-time feeds from EDGAR so you get every Form 4 insider transaction the moment it posts, plus side-by-side analytics that flag option exercises and executive stock transactions. Need the latest Apellis Pharmaceuticals annual report 10-K simplified? Our AI surfaces R&D spend, pipeline milestones, and geographic atrophy market commentary in seconds. Looking for material trial results? The Apellis Pharmaceuticals 8-K material events are explained, highlighting endpoints and FDA interactions.

Because the value of Apellis hinges on clinical progress, each filing type answers different investor questions:

  • 10-K and 10-Q â€� read AI-curated sections on complement immunotherapy pipeline costs and GA launch revenues.
  • 8-K â€� understand pivotal study top-lines without decoding statistical tables.
  • Form 4 â€� monitor leadership confidence through Apellis Pharmaceuticals Form 4 insider transactions real-time.
  • DEF 14A â€� see how proxy statement executive compensation aligns with trial milestones.

Whether you’re analyzing capital needs, assessing competitive risk, or simply wanting Apellis Pharmaceuticals SEC filings explained simply, Stock Titan’s expert analysis turns dense documents into actionable insight so you can focus on decisions, not document hunting.

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On July 14, 2025, Robert M. Jenkins, Executive VP & COO of Essential Properties AGÕæÈ˹ٷ½ty Trust (EPRT), automatically acquired 84 common shares at $0 under a dividend-equivalent adjustment to performance-based RSUs granted in 2022. The award, which will vest on December 31, 2025, raises his direct holding to 35,367 shares. No sales or derivative transactions were reported, and the filing contains no cash consideration or new option grants.

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Form 4 filing for Antero Midstream Corp. (AM) discloses that director Brooks J. Klimley acquired 2,042 shares of AM common stock on 07 July 2025. The shares were received at a stated price of $0.00, implying a grant rather than an open-market purchase. Following the transaction, Klimley’s direct beneficial ownership increased to 75,687 shares. No derivative securities were reported.

The filing is routine in nature, reflecting a modest change in insider ownership and does not provide additional financial or strategic information about Antero Midstream.

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On 1 July 2025, Apellis Pharmaceuticals (NASDAQ: APLS) filed an 8-K announcing a Royalty Buy-Down Agreement with Swedish Orphan Biovitrum (Sobi).

  • Up-front consideration: Sobi will pay Apellis $275 million in cash within five business days of closing.
  • Milestone: Up to $25 million becomes payable upon European Medicines Agency (EMA) approval of Aspaveli for C3G and IC-MPGN.
  • Royalty reduction: In exchange, Apellis will reduce Sobi’s royalty obligations under their October 2020 collaboration by 90 %, effective immediately.
  • Royalty cap: The discount lasts until cumulative reduced royalties equal 1.45× the total amounts paid under the new agreement; thereafter, the original royalty rates resume.
  • Lender consent: Sixth Street Lending Partners consented to the deal. As a condition, Apellis extended by one year the period during which prepayment premiums apply on its May 13 2024 credit facility.

The transaction delivers up to $300 million in non-dilutive liquidity, strengthening Apellisâ€� near-term cash position while delaying—but not eliminating—future royalty income from Aspaveli in Sobi territories. The 1.45× cap preserves long-term upside once Sobi recovers its investment. Investors should weigh immediate balance-sheet relief against the temporary 90 % royalty haircut and the extended prepayment-premium window on existing debt.

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Apellis Pharmaceuticals, Inc. (APLS) filed a Form 4 disclosing that its Vice President & Chief Accounting Officer, James George Chopas, received a grant of 6,250 shares of common stock in the form of restricted stock units (RSUs) on 18 June 2025. The transaction was coded “A(1),â€� indicating an award under the company’s equity compensation plan at no cash cost to the executive (reported price $0). Following the grant, Chopasâ€� total beneficial ownership increased to 54,205 shares held directly.

The RSUs vest over a two-year period: 50 % on the first anniversary of the grant date and the remaining 50 % on the second anniversary, contingent upon continued employment. No derivative securities were acquired or disposed of, and the filing does not reference any Rule 10b5-1 trading plan. The filing was signed on 20 June 2025 by attorney-in-fact David Watson.

From an investor perspective, this is a routine executive equity award intended to align management incentives with shareholder interests. It does not change the company’s capital structure in a material way and is unlikely to affect near-term financial performance or valuation.

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FAQ

What is the current stock price of Apellis Pharmace (APLS)?

The current stock price of Apellis Pharmace (APLS) is $18.95 as of July 29, 2025.

What is the market cap of Apellis Pharmace (APLS)?

The market cap of Apellis Pharmace (APLS) is approximately 2.5B.

What is the core focus of Apellis Pharmaceuticals?

Apellis Pharmaceuticals is a biopharmaceutical company focused on developing therapies that target the complement system, particularly by inhibiting the C3 protein, to treat diseases with high unmet needs.

How does complement immunotherapy work?

Complement immunotherapy involves targeting key components of the immune system's complement cascade, such as C3, to modulate immune responses and prevent the progression of diseases in areas like ophthalmology, hematology, and nephrology.

Which therapeutic areas does Apellis address?

The company targets a range of therapeutic areas including geographic atrophy in age-related macular degeneration, paroxysmal nocturnal hemoglobinuria, and rare kidney diseases like C3 glomerulopathy and IC-MPGN.

How does Apellis differentiate itself from competitors?

Apellis differentiates itself by focusing on the underlying mechanisms of disease through complement inhibition. Its cutting-edge approach and robust clinical data underline a unique scientific value proposition within the biopharmaceutical industry.

What are some of Apellis' key products?

Apellis has developed and commercialized therapies based on complement inhibition, including approved products for treating retinal diseases and rare hematological conditions, with additional candidates in clinical development for kidney diseases.

What is the significance of targeting C3 in disease treatment?

Targeting C3 is significant because it is a central protein in the complement cascade. By inhibiting C3, Apellis� therapies have the potential to modify the disease process at its source, offering the prospect of more effective and lasting treatment outcomes.

How does Apellis generate revenue?

The company generates revenue through the commercialization of its approved therapies and by advancing a pipeline of investigational products, supported by clinical trials and strategic collaborations that expand its market reach.

What should investors know about Apellis' scientific approach?

Investors should note that Apellis� approach is grounded in advanced immunological research. By leveraging complement inhibition, the company provides innovative, disease-modifying therapies that address the fundamental causes of complex conditions.
Apellis Pharmace

NASDAQ:APLS

APLS Rankings

APLS Stock Data

2.46B
106.64M
13.86%
103.5%
16.58%
Biotechnology
Pharmaceutical Preparations
United States
WALTHAM