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Northwest Biotherapeutics Announces the Passing of Its Senior Vice President and General Counsel, Mr. Les Goldman

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Northwest Biotherapeutics (OTCQB:NWBO), a biotechnology company developing DCVax® personalized immune therapies for solid tumor cancers, has announced the passing of its Senior Vice President and General Counsel, Mr. Les Goldman, due to a stroke.

The company, which focuses on developing personalized immunotherapy products, has completed a 331-patient Phase III trial of DCVax-L for glioblastoma (GBM) and submitted a MAA for commercial approval in the UK. Additionally, NWBO has completed a 40-patient Phase I trial of DCVax-Direct for inoperable solid tumor cancers and plans to pursue Phase II trials this year.

Northwest Biotherapeutics (OTCQB:NWBO), società biotecnologica che sviluppa terapie immunitarie personalizzate DCVax® per tumori solidi, ha annunciato la scomparsa del suo Senior Vice President e General Counsel, Mr. Les Goldman, a seguito di un ictus.

La società, focalizzata su prodotti di immunoterapia personalizzata, ha completato un trial di fase III su 331 pazienti con DCVax-L per il glioblastoma (GBM) e ha presentato una MAA per l'approvazione commerciale nel Regno Unito. Inoltre, NWBO ha concluso un trial di fase I su 40 pazienti con DCVax-Direct per tumori solidi inoperabili e intende avviare studi di fase II nel corso dell'anno.

Northwest Biotherapeutics (OTCQB:NWBO), una biotecnológica que desarrolla terapias inmunológicas personalizadas DCVax® para tumores sólidos, ha anunciado el fallecimiento de su Senior Vice President y General Counsel, Mr. Les Goldman, a causa de un ictus.

La compañía, centrada en el desarrollo de productos de inmunoterapia personalizada, completó un ensayo fase III con 331 pacientes de DCVax-L para glioblastoma (GBM) y presentó una MAA para la aprobación comercial en el Reino Unido. Además, NWBO ha finalizado un ensayo fase I con 40 pacientes de DCVax-Direct para tumores sólidos inoperables y planea iniciar ensayos de fase II este año.

Northwest Biotherapeutics (OTCQB:NWBO), 고형종양 대� 맞춤� 면역치료� DCVax®� 개발하는 생명공학 기업�, 선임 부사장 � 법무총괄� Les Goldman �가 뇌졸중으� 별세했다� 발표했습니다.

개인맞춤� 면역치료� 개발� 주력하는 � 회사� 교모세포�(GBM) 치료� DCVax-L� 대� 331� 대상의 3� 임상시험� 완료하고 영국에서 상업 허가� 위한 MAA� 제출했습니다. 또한 NWBO� 수술 불가 고형� 대� DCVax-Direct� 40� 대� 1� 임상시험� 마쳤으며, 올해 2� 시험� 추진� 계획입니�.

Northwest Biotherapeutics (OTCQB:NWBO), une société de biotechnologie développant des thérapies immunitaires personnalisées DCVax® pour les tumeurs solides, a annoncé le décès de son Senior Vice President et General Counsel, M. Les Goldman, à la suite d'un AVC.

La société, qui se consacre au développement de produits d'immunothérapie personnalisée, a achevé un essai de phase III portant sur 331 patients de DCVax-L pour le glioblastome (GBM) et a déposé une MAA pour obtenir l'autorisation commerciale au Royaume-Uni. De plus, NWBO a terminé un essai de phase I portant sur 40 patients de DCVax-Direct pour des tumeurs solides inopérables et prévoit de lancer des essais de phase II cette année.

Northwest Biotherapeutics (OTCQB:NWBO), ein Biotechnologieunternehmen, das personalisierte DCVax®-Immuntherapien für solide Tumoren entwickelt, hat den Tod seines Senior Vice President und General Counsel, Mr. Les Goldman, infolge eines Schlaganfalls bekanntgegeben.

Das Unternehmen, das sich auf die Entwicklung personalisierter Immuntherapien konzentriert, hat eine Phase-III-Studie mit 331 Patienten zu DCVax-L bei Glioblastom (GBM) abgeschlossen und eine MAA zur kommerziellen Zulassung im Vereinigten Königreich eingereicht. Außerdem hat NWBO eine Phase-I-Studie mit 40 Patienten zu DCVax-Direct bei inoperablen soliden Tumoren abgeschlossen und plant, dieses Jahr Phase-II-Studien durchzuführen.

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BETHESDA, Md., Aug. 18, 2025 /PRNewswire/ -- Northwest Biotherapeutics (OTCQB:NWBO) (the "Company" or "NW Bio"), a biotechnology company developing DCVax® personalized immune therapies for solid tumor cancers, announced with deep sadness the passing of its Senior Vice President and General Counsel, Mr. Les Goldman, due to a stroke. 

The Company greatly appreciates Mr. Goldman's many years of intensive work on behalf of the Company, its shareholders and cancer patients. The Company extends its deepest condolences to the Goldman family. Mr. Goldman's duties are being assumed by other members of the Company's management team at this time.

About Northwest Biotherapeutics

Northwest Biotherapeutics is a biotechnology company focused on developing personalized immunotherapy products that are designed to treat cancers more effectively than current treatments, without toxicities of the kind associated with chemotherapies, and on a cost-effective basis. The Company has a broad platform technology for DCVax® dendritic cell-based vaccines. The Company's lead program involves DCVax®-L treatment for glioblastoma (GBM). GBM is the most aggressive and lethal form of primary brain cancer, and is an "orphan disease." The Company has completed a 331-patient Phase III trial of DCVax-L for GBM, presented the results in scientific meetings, published the results in JAMA Oncology and submitted a MAA for commercial approval in the UK. The MAAis currently undergoing review. The Company has also developed DCVax®-Direct for inoperable solid tumor cancers. It has completed a 40-patient Phase I trial and plans to pursue Phase II trials this year. The Company previously conducted a Phase I/II trial with DCVax-L for advanced ovarian cancer together with the University of Pennsylvania.

Disclaimer

Statements made in this news release that are not historical facts, including statements concerning plans for DCVax® are forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. Words such as "expect," "believe," "intend," "design," "plan," "continue," "may," "will," "anticipate," and similar expressions are intended to identify forward-looking statements, although not all forward-looking statements contain these identifying words. Actual results may differ materially from those projected in any forward-looking statement. Readers should not rely upon forward-looking statements. There are a number of important factors that could cause actual results to differ materially from those anticipated, including, without limitation, risks related to delays or uncertainties in regulatory processes and decisions, risks related to the Company's ability to achieve timely performance of third parties, risks related to whether the Company's products will be viewed as demonstrating safety and efficacy, risks related to the Company's ongoing ability to raise additional capital, and other risks included in the Company's Securities and Exchange Commission ("SEC") filings. Additional information on the foregoing risk factors and other factors, including Risk Factors, which could affect the Company's results, is included in its SEC filings. Finally, there may be other factors not mentioned above or included in the Company's SEC filings that may cause actual plans, results or timelines to differ materially from those projected in any forward-looking statement. The Company assumes no obligation to update any forward-looking statements as a result of new information, future events or developments, except as required by securities laws.

CONTACT

Northwest Biotherapeutics

Dave Innes
804-513-6758
[email protected]

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SOURCE Northwest Biotherapeutics

FAQ

Who was Les Goldman at Northwest Biotherapeutics (NWBO)?

Les Goldman served as the Senior Vice President and General Counsel at Northwest Biotherapeutics until his passing due to a stroke in August 2025.

What is the current status of Northwest Biotherapeutics' DCVax-L treatment?

NWBO has completed a 331-patient Phase III trial for DCVax-L in glioblastoma (GBM), published results in JAMA Oncology, and submitted a MAA for commercial approval in the UK, which is under review.

What clinical trials has Northwest Biotherapeutics (NWBO) completed?

NWBO has completed a 331-patient Phase III trial of DCVax-L for glioblastoma, a 40-patient Phase I trial of DCVax-Direct for inoperable solid tumors, and a Phase I/II trial with DCVax-L for advanced ovarian cancer.

Who will take over Les Goldman's responsibilities at NWBO?

Mr. Goldman's duties are being assumed by other members of the Company's management team at this time.

What are Northwest Biotherapeutics' main products under development?

NWBO is developing DCVax® dendritic cell-based vaccines, including DCVax-L for glioblastoma and DCVax-Direct for inoperable solid tumor cancers.
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Biotechnology
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United States
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