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NuCana plc (Nasdaq: NCNA) has filed a Form 6-K to notify investors of an upcoming change to its American Depositary Share (ADS) programme. The company will consolidate its ADSs by altering the conversion ratio from 1 ADS = 25 ordinary shares to 1 ADS = 5,000 ordinary shares, producing the economic effect of a 1-for-200 reverse ADS split. According to the filing, the action is purely mechanical and will not affect any holder鈥檚 proportional equity interest. The revised ratio is expected to take effect at the start of trading on the Nasdaq Capital Market on 8 August 2025 (U.S. Eastern Time). The document contains no financial statements or operational updates; it simply details the corporate action, incorporates the related press release (Exhibit 99.1) by reference, and states that the information will be included in several of NuCana鈥檚 registration statements. Standard forward-looking statement language regarding potential market impacts is also provided.

NuCana plc (NASDAQ: NCNA) faces heightened delisting risk. The company disclosed that on July 8, 2025 it received a second notice from Nasdaq after its American Depositary Shares closed below $0.10 for 10 consecutive trading days (period ended July 7, 2025). This follows an earlier June 18, 2025 notice for falling below the $1.00 minimum bid price, which granted NuCana until December 15, 2025 to regain compliance. Under Nasdaq Listing Rule 5810(c)(3)(A)(iii), falling below $0.10 triggers imminent delisting unless the issuer requests a hearing.
NuCana intends to timely request a hearing before the Nasdaq Hearings Panel. The hearing request will automatically stay any suspension or delisting action pending the Panel鈥檚 decision, giving management additional time to present a compliance plan or pursue corporate actions (e.g., reverse split) to restore the share price.

No financial results, operational updates, or transactions were included; the 6-K focuses solely on the listing status. The information is incorporated by reference into the company鈥檚 existing Form F-3 and S-8 registration statements.

uniQure N.V. (QURE) has filed a Form S-8 with the SEC to register an additional 2,400,000 ordinary shares (par value 鈧�0.05) for issuance under its Amended and Restated 2014 Share Incentive Plan. The increase was approved by the board on 15 Apr 2025 and by shareholders on 11 Jun 2025. These shares are in addition to roughly 15.9 million ordinary shares previously registered on six earlier S-8 filings covering the same plan. No financial statements or earnings data are included; the filing is purely administrative, enabling future equity-based compensation grants. Key exhibits include the Dutch legal opinion (Ex. 5.1), auditor consent (Ex. 23.2) and the full 2014 Plan (Ex. 99.1). While the move supports employee retention and alignment, it also represents potential shareholder dilution once the options or awards are exercised.

NuCana plc (Nasdaq: NCNA) has filed a Form 424B5 prospectus supplement establishing an at-the-market (ATM) equity program that permits the sale, from time to time, of American Depositary Shares (ADSs) with an aggregate offering limit of up to US$100 million. Each ADS represents 25 ordinary shares with a nominal value of 拢0.0004 per share.

Key terms:

• Sales agents: A.G.P./Alliance Global Partners and Laidlaw & Company (UK) Ltd. will act on a best-efforts basis and are deemed 鈥渦nderwriters鈥� under the Securities Act.
• Commission: Agents will receive 3.0 % of gross proceeds; NuCana will also reimburse certain offering expenses and provide customary indemnification.
• Offering format: Sales will be conducted as 鈥渁t-the-market offerings鈥� under Rule 415(a)(4); there is no escrow arrangement and no obligation for agents to place a minimum amount.
• Listing/price reference: ADSs trade on the Nasdaq Capital Market under the symbol 鈥淣CNA鈥�; the last reported price on 26 June 2025 was US$0.0826 per ADS.
• Use of proceeds: Specific uses are not detailed here; investors are directed to the 鈥淯se of Proceeds鈥� section (page S-11) for further information.

The filing highlights standard risk disclosures (pages S-6 onward) and reiterates that NuCana鈥檚 financial statements are prepared under IFRS and presented in pounds sterling.

Overall, the document provides NuCana with flexible access to capital but also introduces potential dilution for existing shareholders, particularly given the company鈥檚 low prevailing share price.

Nvidia Corp. (NVDA) has filed a Form 144 indicating that President and CEO Jen-Hsun Huang intends to sell up to 75,000 shares of common stock on 30 June 2025 through broker Charles Schwab & Co. The planned transaction is valued at approximately $11.8 million, based on the filing鈥檚 stated aggregate market value. The shares were acquired via a Performance Stock Award on 20 March 2024 and will be sold on the NASDAQ exchange. The filing lists 24.4 billion shares outstanding, making the proposed sale an immaterial 0.0003 % of total shares.

The notice also discloses that Huang has executed six sales in the previous three months鈥攖otalling 375,000 shares between 20 June 2025 and 27 June 2025鈥攆or combined gross proceeds of roughly $56.7 million. Together with the upcoming sale, insider disposals reach 450,000 shares within a short window.

Because Form 144 signals an intention rather than a completed trade, the transaction may or may not occur, and no Rule 10b5-1 plan adoption date is provided in the submitted fields. Nonetheless, the filing meets disclosure requirements under SEC Rule 144, offering investors transparency into executive trading activity.