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Jupiter Neurosciences Showcases Nugevia� PWR: Mitochondrial Optimization Supplement Designed to Boost Energy, Endurance, and Recovery

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Jupiter Neurosciences (NASDAQ: JUNS) has announced the launch of Nugevia� PWR, a mitochondrial health supplement designed to enhance cellular energy, endurance, and recovery. The product leverages the company's proprietary JOTROL� resveratrol-based platform technology and will be commercially available in Fall 2025.

The supplement combines JOTROL�, which showed a nine-fold increase in resveratrol bioavailability in Phase I trials, with NovaSOL® solubilized CoQ10. The product targets the longevity and wellness markets, projected to reach $8 trillion by 2030. PWR is designed as a two-capsule daily regimen and will join GLO in Jupiter's Nugevia� product line.

The company positions PWR as a strategic revenue opportunity, aiming to generate high-margin returns to support its therapeutic development programs while addressing growing consumer demand for scientifically validated supplements.

Jupiter Neurosciences (NASDAQ: JUNS) ha annunciato il lancio di Nugevia� PWR, un integratore per la salute mitocondriale progettato per migliorare l'energia cellulare, la resistenza e il recupero. Il prodotto sfrutta la tecnologia proprietaria JOTROL�, basata sul resveratrolo, e sarà disponibile commercialmente nell'autunno 2025.

L'integratore combina JOTROL�, che ha mostrato un aumento di nove volte della biodisponibilità del resveratrolo nelle prove di Fase I, con NovaSOL® CoQ10 solubilizzato. Il prodotto si rivolge ai mercati della longevità e del benessere, previsti raggiungere un valore di 8 trilioni di dollari entro il 2030. PWR è pensato come un regime quotidiano di due capsule e si unirà a GLO nella linea di prodotti Nugevia� di Jupiter.

L'azienda considera PWR un'opportunità strategica di ricavo, con l'obiettivo di generare ritorni ad alto margine per sostenere i suoi programmi di sviluppo terapeutico, rispondendo al contempo alla crescente domanda dei consumatori di integratori convalidati scientificamente.

Jupiter Neurosciences (NASDAQ: JUNS) ha anunciado el lanzamiento de Nugevia� PWR, un suplemento para la salud mitocondrial diseñado para mejorar la energía celular, la resistencia y la recuperación. El producto utiliza la tecnología patentada JOTROL�, basada en resveratrol, y estará disponible comercialmente en el otoño de 2025.

El suplemento combina JOTROL�, que mostró un aumento de nueve veces en la biodisponibilidad del resveratrol en los ensayos de Fase I, con CoQ10 solubilizado NovaSOL®. El producto está dirigido a los mercados de longevidad y bienestar, que se proyectan alcanzar un valor de 8 billones de dólares para 2030. PWR está diseñado como un régimen diario de dos cápsulas y se unirá a GLO en la línea de productos Nugevia� de Jupiter.

La compañía posiciona PWR como una oportunidad estratégica de ingresos, con el objetivo de generar retornos de alto margen para apoyar sus programas de desarrollo terapéutico, mientras responde a la creciente demanda de los consumidores por suplementos validados científicamente.

Jupiter Neurosciences (NASDAQ: JUNS)ëŠ� ì„¸í¬ ì—너지, 지구력 ë°� íšŒë³µë ¥ì„ í–¥ìƒì‹œí‚¤ê¸� 위해 설계ë� 미토콘드리아 ê±´ê°• ë³´ì¡°ì œì¸ Nugeviaâ„� PWRì� 출시ë¥� 발표했습니다. ì� ì œí’ˆì€ íšŒì‚¬ì� ë…ì ì ì¸ JOTROLâ„� 레스베ë¼íŠ¸ë¡¤ 기반 플랫í� 기술ì� 활용하며, 2025ë…� ê°€ì�ì—� ìƒì—…ì ìœ¼ë¡� 출시ë� 예정입니ë‹�.

ì� 보조제는 1ìƒ� 시험ì—서 레스베ë¼íŠ¸ë¡¤ ìƒì²´ì´ìš©ë¥ ì´ 9ë°� ì¦ê°€í•� JOTROL™과 NovaSOL® 용해í˜� CoQ10ì� 결합했습니다. ì� ì œí’ˆì€ 2030년까지 8ì¡� 달러ì—� 달할 것으ë¡� 예ìƒë˜ëŠ” 장수 ë°� 웰니ìŠ� 시장ì� 목표ë¡� 합니ë‹�. PWRì€ í•˜ë£¨ ë‘� ìº¡ìŠ ë³µìš© 체계ë¡� 설계ë˜ì—ˆìœ¼ë©°, Jupiterì� Nugeviaâ„� ì œí’ˆêµ°ì— GLO와 함께 합류í•� 예정입니ë‹�.

회사ëŠ� PWRì� ì „ëžµì � ìˆ˜ìµ ê¸°íšŒë¡� ìžë¦¬ë§¤ê¹€í•˜ì—¬, 치료 개발 프로그램ì� ì§€ì›í•˜ëŠ� 고수ìµì„ 창출하고 과학ì ìœ¼ë¡� ê²€ì¦ëœ ë³´ì¡°ì œì— ëŒ€í•� 소비ìž� 수요 ì¦ê°€ì—� 대ì‘하ëŠ� ê²ƒì„ ëª©í‘œë¡� 하고 있습니다.

Jupiter Neurosciences (NASDAQ : JUNS) a annoncé le lancement de Nugevia� PWR, un complément pour la santé mitochondriale conçu pour améliorer l'énergie cellulaire, l'endurance et la récupération. Ce produit utilise la technologie propriétaire JOTROL� à base de resvératrol et sera disponible commercialement à l'automne 2025.

Le complément associe JOTROL�, qui a démontré une augmentation de neuf fois la biodisponibilité du resvératrol lors des essais de phase I, à la CoQ10 solubilisée NovaSOL®. Ce produit cible les marchés de la longévité et du bien-être, estimés à 8 000 milliards de dollars d'ici 2030. PWR est conçu pour être pris en deux capsules par jour et viendra compléter la gamme Nugevia� de Jupiter, aux côtés de GLO.

L'entreprise positionne PWR comme une opportunité stratégique de revenus, visant à générer des marges élevées pour soutenir ses programmes de développement thérapeutique tout en répondant à la demande croissante des consommateurs pour des compléments scientifiquement validés.

Jupiter Neurosciences (NASDAQ: JUNS) hat die Einführung von Nugevia� PWR angekündigt, einem Nahrungsergänzungsmittel zur mitochondrialen Gesundheit, das darauf ausgelegt ist, die zelluläre Energie, Ausdauer und Erholung zu verbessern. Das Produkt nutzt die firmeneigene JOTROL�-Technologie auf Resveratrol-Basis und wird im Herbst 2025 kommerziell erhältlich sein.

Das Supplement kombiniert JOTROL�, das in Phase-I-Studien eine neunfach erhöhte Resveratrol-Bioverfügbarkeit zeigte, mit NovaSOL® löslichem CoQ10. Das Produkt richtet sich an die Märkte für Langlebigkeit und Wellness, die bis 2030 voraussichtlich 8 Billionen US-Dollar erreichen werden. PWR ist als tägliche Einnahme von zwei Kapseln konzipiert und wird sich der GLO-Produktlinie in Jupiters Nugevia�-Portfolio anschließen.

Das Unternehmen sieht in PWR eine strategische Umsatzchance, mit dem Ziel, margenstarke Erträge zu generieren, um seine therapeutischen Entwicklungsprogramme zu unterstützen und gleichzeitig der wachsenden Verbrauchernachfrage nach wissenschaftlich validierten Nahrungsergänzungsmitteln gerecht zu werden.

Positive
  • JOTROL demonstrated 9x increase in resveratrol bioavailability in Phase I trials
  • Product targets longevity and wellness markets projected to reach $8 trillion by 2030
  • Strategic expansion into high-margin consumer supplement market
  • Leverages existing proprietary technology across both pharmaceutical and consumer verticals
Negative
  • None.

PWR delivers science-driven cellular energy and recovery support as part of Jupiter’s expanding longevity supplement portfolio

Jupiter, Florida, June 30, 2025 (GLOBE NEWSWIRE) -- Jupiter Neurosciences, Inc. (NASDAQ: JUNS) ("Jupiter" or the "Company"), a clinical-stage pharmaceutical company developing JOTROL�, a patented resveratrol-based platform, is pleased to unveil Nugevia� PWR, a daily mitochondrial health supplement scientifically formulated to support cellular energy, endurance, and recovery. PWR targets a rapidly expanding consumer demand for science-backed, clinically validated supplements, providing a high-margin growth opportunity within the longevity and wellness markets, projected to reach $8 trillion by 2030, with commercial availability expected in Fall 2025.

Clinically Validated Cellular Fuel

Built on the same pharmaceutical-grade delivery platform behind Jupiter's CNS drug candidates, PWR pairs JOTROL� with a curated blend of mitochondrial support ingredients to help optimize energy production, protect against oxidative stress, and enhance physical performance. The formulation was developed for adults seeking sustained strength, metabolic resilience, and recovery support grounded in clinical science.

"With PWR, we are tapping into the bioenergetic core of healthy aging," said Christer Rosén, Chairman and CEO of Jupiter Neurosciences. "By leveraging our JOTROL� platform beyond the clinic, we're offering a science-first approach to vitality and endurance that meets growing demand from consumers who want more than just a quick energy boost."

Advanced Mitochondrial Science for Endurance and Recovery

JOTROL�, which demonstrated a nine-fold increase in resveratrol bioavailability in Phase I trials, promotes mitochondrial biogenesis and energy metabolism through activation of longevity pathways. In PWR, JOTROL� is combined with NovaSOL® solubilized CoQ10, a highly bioavailable antioxidant proven to enhance mitochondrial energy production and muscle function. Together, these ingredients create a powerful synergy—boosting both the quantity and quality of mitochondria, resulting in improved energy, endurance, and muscle recovery.

Taken together, these ingredients work in synergy to:

  • Boost mitochondrial energy output
  • Reduce exercise-related oxidative stress
  • Support muscle recovery and stamina
  • Promote sustained physical and mental performance

A Strategic Growth Catalyst

PWR reinforces Jupiter's strategy of monetizing its proprietary science across both pharmaceutical and consumer verticals. The supplement joins GLO in the broader Nugevia� rollout, which the Company expects to serve as a high-margin revenue driver supporting therapeutic development.

"Each product in the Nugevia line represents both a scientific achievement and a strategic revenue opportunity," added Rosén. "With PWR, we're providing a differentiated option in the crowded energy space—one that delivers long-term benefits, not just a short-term boost."

Nugevia PWR is designed as a two-capsule-per-day regimen for optimal compliance and absorption.

A digital press kit, including high-resolution product imagery and key brand information, is available at .

About Jupiter Neurosciences, Inc.

Jupiter Neurosciences is a clinical-stage pharmaceutical company pursuing a dual-path strategy to address neuroinflammation and promote healthy aging. The Company is advancing a therapeutic pipeline targeting central nervous system (CNS) disorders and rare diseases, while also expanding into the consumer longevity market with its Nugevia� product line. Both efforts are powered by JOTROL�, Jupiter’s proprietary, enhanced resveratrol formulation that has demonstrated significantly improved bioavailability. Nugevia brings clinical-grade science to the supplement space, supporting mental clarity, skin health, and mitochondrial function. The Company’s prescription pipeline is focused broadly on CNS disorders, presently with a Phase IIa in Parkinson’s disease, includeing indications such as Alzheimer’s Disease, Mucopolysaccharidoses Type I, Friedreich’s Ataxia, and MELAS. More information may be found on the Company’s website .

About JOTROL

Resveratrol is one of the world’s most extensively researched molecules. Thorough evaluation has shown that for the compound to be effective, it requires a high C-Max (~300 ng/ml of resveratrol in plasma), achievable only with doses exceeding 3 grams using earlier resveratrol products. Poor bioavailability has been a well-documented issue with resveratrol. Doses over 2 grams have been associated with severe gastrointestinal (GI) side effects, which have prevented the compound from receiving regulatory approval for any indication.

Jupiter Neurosciences (JUNS) conducted a Phase I study demonstrating that JOTROL� achieves over nine times higher bioavailability compared to resveratrol used in earlier clinical trials (e.g., Turner et al., MCI/Early Alzheimer’s Disease trial, and Yui et al., Friedreich’s Ataxia trial). The results of this Phase I study, which will be cross-referenced in all upcoming JOTROL� trials, were published in the Journal of Alzheimer’s Disease and AAPS Open in February 2022. JUNS is now advancing JOTROL� toward a Phase IIa trial in Parkinson’s Disease.

In addition to its therapeutic applications, JOTROL� serves as the foundation for Jupiter’s Nugevia� consumer supplement line. By leveraging the same clinically validated delivery technology, Nugevia� introduces pharmaceutical-grade bioavailability into the wellness space, offering targeted support for cognitive health, skin vitality, and cellular energy.

FORWARD-LOOKING STATEMENTS

Certain statements in this announcement are forward-looking statements. These forward-looking statements involve known and unknown risks and uncertainties and are based on the Company’s current expectations, including the Company’s ability to generate revenues from the sale of JOTROL products to consumers through the DTC model. Investors can find many (but not all) of these statements by the use of words such as “approximates,� “believes,� “hopes,� “expects,� “anticipates,� “estimates,� “projects,� “intends,� “plans,� “will,� “would,� “should,� “could,� “may� or other similar expressions. Although the Company believes that the expectations expressed in these forward-looking statements are reasonable, it cannot assure you that such expectations will turn out to be correct. The Company cautions investors that actual results may differ materially from the anticipated results and encourages investors to read the risk factors contained in the Company’s final prospectus and other reports it files with the SEC before making any investment decisions regarding the Company’s securities. The Company undertakes no obligation to update or revise publicly any forward-looking statements to reflect subsequent occurring events or circumstances, or changes in its expectations, except as may be required by law.

Contact:
Dave Gentry
RedChip Companies, Inc.
1-407-644-4256
1-800-RED-CHIP (733-2447)


FAQ

When will Jupiter Neurosciences (JUNS) launch Nugevia PWR?

Jupiter Neurosciences plans to launch Nugevia PWR in Fall 2025.

What is the key technology behind Jupiter Neurosciences' Nugevia PWR supplement?

Nugevia PWR is built on Jupiter's JOTROL� resveratrol-based platform, which showed 9x increased bioavailability in Phase I trials, combined with NovaSOL® solubilized CoQ10.

What is the recommended dosage for Jupiter Neurosciences' Nugevia PWR?

Nugevia PWR is designed as a two-capsule-per-day regimen for optimal compliance and absorption.

What market opportunity is Jupiter Neurosciences (JUNS) targeting with Nugevia PWR?

Jupiter is targeting the longevity and wellness markets, which are projected to reach $8 trillion by 2030.

How does Nugevia PWR fit into Jupiter Neurosciences' business strategy?

PWR is positioned as a high-margin revenue driver to support therapeutic development while expanding into the consumer supplement market.
JUPITER NEUROSCIENCES, INC.

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